Search Results - "Cawthorne, M.A."

Metabolic programming: can it be manipulated? by Cawthorne, M.A

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Fetal origins of insulin resistance and obesity by Stocker, Claire J., Arch, Jonathan R. S., Cawthorne, Michael A.

“…A number of epidemiological studies worldwide have demonstrated a relationship between poor early growth and an increased susceptibility to insulin resistance,…”
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Comparison of the physiological effects of zinc-[formula omitted]2-glycoprotein and the [formula omitted]3-adrenoceptor agonist, BRL 35135, in male C57Bl6 ob/ob mice by Wargent, E.T., Zaibi, M.S., Arch, J.R.S., Cawthorne, M.A., Bing, C., Stocker Lore, C.J.

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Leptin Action in Intestinal Cells by Morton, Nicholas M., Emilsson, Valur, Liu, Yong-Ling, Cawthorne, Michael A.

“…The adipocyte hormone leptin activates signal transducer and activator of transcription 3 (STAT3) in the hypothalamus, mediating increased satiety and…”
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Leanness in postnatally nutritionally programmed rats is associated with increased sensitivity to leptin and a melanocortin receptor agonist and decreased sensitivity to neuropeptide Y by Stocker, C J, Wargent, E T, Martin-Gronert, M S, Cripps, R L, O'Dowd, J F, Zaibi, M S, Cottrell, E C, Mercer, J G, Duncan, J S, Cawthorne, M A, Ozanne, S E, Arch, J R S

“…Background: Pups of normally nourished dams that are cross-fostered after birth to dams fed a low-protein (8% by weight) diet (postnatal low protein (PLP))…”
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Thermogenic and anorectic effects of ephedrine and congeners in mice and rats by Arch, J R, Ainsworth, A T, Cawthorne, M A

“…(-)-Ephedrine has been shown to increase energy expenditure and cause the loss of body fat in rats and mice. The present study compares the effects of (-)- and…”
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Retinoid X receptor agonists have anti-obesity effects and improve insulin sensitivity in Zucker fa/fa rats by Liu, Y.L, Sennitt, M.V, Hislop, D.C, Crombie, D.L, Heyman, R.A, Cawthorne, M.A

“…OBJECTIVE: To investigate whether retinoid X receptor agonists act as insulin sensitizers and compare their effects with that of thiazolidinedione BRL 49653 in…”
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In vivo effects of carbon tetrachloride and chloroform on liver and kidney glucose-6-phosphatase in mice by Cawthorne, M A, Palmer, E D, Bunyan, J, Green, J

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The effect of ethoxyquin on the mortality of sheep treated with DDT and carbon tetrachloride by Cawthorne, M A, Murrell, E A, Bunyan, J, Leiper, J W, Green, J, Watkins, J H

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Non thiazolidinedione antihyperglycaemic agents. 1: α-Heteroatom substituted β-phenylpropanoic acids by Buckle, D.R., Cantello, B.C.C., Cawthorne, M.A., Coyle, P.J., Dean, D.K., Faller, A., Haigh, D., Hindley, R.M., Jefcott, L.J., Lister, C.A., Pinto, I.L., Rami, H.K., Smith, D.G., Smith, S.A.

“…The 5-benzylthiazolidine-2,4-dione moiety of insulin sensitising antidiabetic agents can be replaced by a range of α-heteroatom functionalised…”
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The Thiazolidinedione Insulin Sensitiser, BRL 49653, Increases the Expression of PPAR-γ and aP2in Adipose Tissue of High-Fat-Fed Rats by Pearson, S.L., Cawthorne, M.A., Clapham, J.C., Dunmore, S.J., Holmes, S.D., Moore, G.B.T., Smith, S.A., Tadayyon, M.

“…The effects of the thiazolidinedione insulin sensitiser BRL 49653 on plasma leptin concentrations and on epididymal fat OB, PPAR-γ and aP2mRNA expression were…”
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Non thiazolidinedione antihyperglycaemic agents. 2: α-Carbon substituted β-phenylpropanoic acids1 by Buckle, D.R., Cantello, B.C.C., Cawthorne, M.A., Coyle, P.J., Dean, D.K., Faller, A., Haigh, D., Hindley, R.M., Jefcott, L.J., Lister, C.A., Pinto, I.L., Rami, H.K., Smith, D.G., Smith, S.A.

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Non thiazolidinedione antihyperglycaemic agents. 2: α-Carbon substituted β-phenylpropanoic acids 1 by Buckle, D.R., Cantello, B.C.C., Cawthorne, M.A., Coyle, P.J., Dean, D.K., Faller, A., Haigh, D., Hindley, R.M., Jefcott, L.J., Lister, C.A., Pinto, I.L., Rami, H.K., Smith, D.G., Smith, S.A.

“…The thiazolidine-2,4-dione ring of insulin sensitising antidiabetic agents can be replaced by α-acyl-, α-alkyl- and α-(aralkyl)-carboxylic acids. Inclusion of…”
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Reduced maximum capacity of glycolysis in brown adipose tissue of genetically obese, diabetic (db/db) mice and its restoration following treatment with a thermogenic β-adrenoceptor agonist by Young, P., Cawthorne, M.A., Levy, Alison L., Wilson, Karen

“…The maximal activities of the key glycolytic enzymes hexokinase and 6-phosphofructokinase, were reduced in brown adipose tissue in db/db mice compared to their…”
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A simple apparatus for comparative measurements of energy expenditure in human subjects: the thermic effect of caffeine by Hollands, M A, Arch, J R S, Cawthorne, M A

“…A simple inexpensive indirect calorimeter that is suitable for the estimation of energy expenditure in man is described. Its usefulness is demonstrated by a…”
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Adjuvant-induced arthritis and drug-metabolizing enzymes by Cawthorne, M A, Palmer, E D, Green, J

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Stimulation of insulin secretion from mouse pancreatic islets, maintained in tissue culture, by the pituitary neurointermediate lobe of the genetically obese mouse (ob/ob) by Beloff-Chain, A, Billingham, N, Cawthorne, M A

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Influence of fasting on basal and pituitary-stimulated insulin secretion from perifused pancreatic islets of lean and obese mice by Beloff-Chain, Anne, Bogdanovic, S., Cawthorne, M.A.

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Effects of vasopressin on lipogenesis in obese mice by Edwards, M.W., Brooks, Sarah L., Gove, C.D., Hems, D.A., Cawthorne, M.A.

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Studies on unidentified growth factors. 2. progressin, a growth factor for chicks by Bunyan, J, Murrell, E.A, Cawthorne, M.A, Redman, B.T

“…1. Chicks at 10 d of age were given diets containing all the nutrients known to be required, with L-amino acids in place of protein. Dietary supplements were…”
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