Search Results - "Cawthorne, Christopher J."
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Silencing microRNA-330-5p increases MMP1 expression and promotes an invasive phenotype in oesophageal adenocarcinoma
Published in BMC cancer (07-08-2019)“…Many patients diagnosed with oesophageal adenocarcinoma (OAC) present with advanced disease and approximately half present with metastatic disease. Patients…”
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Hypoxia-Mediated Down-Regulation of Bid and Bax in Tumors Occurs via Hypoxia-Inducible Factor 1-Dependent and -Independent Mechanisms and Contributes to Drug Resistance
Published in Molecular and Cellular Biology (01-04-2004)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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64Cu PET Imaging of the CXCR4 Chemokine Receptor Using a Cross-Bridged Cyclam Bis-Tetraazamacrocyclic Antagonist
Published in The Journal of nuclear medicine (1978) (01-01-2020)“…mune diseases, and during stem cell–based repair processes after stroke and myocardial infarction. Previously reported PET imaging agents targeting CXCR4…”
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What we can learn from deep space communication for reproducible bioimaging and data analysis
Published in Molecular systems biology (02-01-2024)“…Multiple initiatives have attempted to define and recommend the annotation of images with metadata. However, proper documentation of complex and evolving…”
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Development of an anatomically correct mouse phantom for dosimetry measurement in small animal radiotherapy research
Published in Physics in medicine & biology (21-06-2019)“…Significant improvements in radiotherapy are likely to come from biological rather than technical optimization, for example increasing tumour radiosensitivity…”
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In vivo validation of 68Ga-labeled AMD3100 conjugates for PET imaging of CXCR4
Published in Nuclear medicine and biology (01-05-2023)“…The chemokine receptor CXCR4 has been shown to be over-expressed in multiple types of cancer and is usually associated with aggressive phenotypes and poor…”
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PI3K inhibition as a novel therapeutic strategy for neoadjuvant chemoradiotherapy resistant oesophageal adenocarcinoma
Published in British journal of radiology (01-03-2021)“…Neoadjuvant chemoradiotherapy (neo-CRT) prior to surgery is the standard of care for oesophageal adenocarcinoma (OAC) patients. Unfortunately, most patients…”
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64 Cu PET Imaging of the CXCR4 Chemokine Receptor Using a Cross-Bridged Cyclam Bis-Tetraazamacrocyclic Antagonist
Published in Journal of Nuclear Medicine (01-01-2020)“…Expression of the chemokine receptor chemokine C-X-C motif receptor 4 (CXCR4) plays an important role in cancer metastasis, in autoimmune diseases, and during…”
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Influence of Multiple Animal Scanning on Image Quality for the Sedecal SuperArgus2R Preclinical PET Scanner
Published in Frontiers in physics (12-01-2021)“…Background: Increased throughput in small animal preclinical studies using positron emission tomography leads to reduced costs and improved efficiency of…”
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Translation of HDAC6 PET Imaging Using [18F]EKZ-001–cGMP Production and Measurement of HDAC6 Target Occupancy in Nonhuman Primates
Published in ACS chemical neuroscience (01-04-2020)“…Histone deacetylase 6 (HDAC6) is a multifunctional cytoplasmic enzyme involved in diverse cellular processes such as intracellular transport and protein…”
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11
In vivo validation of 68 Ga-labeled AMD3100 conjugates for PET imaging of CXCR4
Published in Nuclear medicine and biology (01-05-2023)“…The chemokine receptor CXCR4 has been shown to be over-expressed in multiple types of cancer and is usually associated with aggressive phenotypes and poor…”
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12
Translation of HDAC6 PET imaging using [18F]EKZ-001 – cGMP production and measurement of HDAC6 target occupancy in NHPs
Published in ACS chemical neuroscience (19-03-2020)“…Histone deacetylase 6 (HDAC6) is a multifunctional cytoplasmic enzyme involved in diverse cellular processes such as intracellular transport and protein…”
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