Search Results - "Cavaretta, John P"
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PRMT5 activates AKT via methylation to promote tumor metastasis
Published in Nature communications (08-07-2022)“…Protein arginine methyltransferase 5 (PRMT5) is the primary methyltransferase generating symmetric-dimethyl-arginine marks on histone and non-histone proteins…”
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Reduced axonal surface expression and phosphoinositide sensitivity in Kv7 channels disrupts their function to inhibit neuronal excitability in Kcnq2 epileptic encephalopathy
Published in Neurobiology of disease (01-10-2018)“…Neuronal Kv7/KCNQ channels are voltage-gated potassium channels composed of Kv7.2/KCNQ2 and Kv7.3/KCNQ3 subunits. Enriched at the axonal membrane, they…”
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Polarized axonal surface expression of neuronal KCNQ potassium channels is regulated by calmodulin interaction with KCNQ2 subunit
Published in PloS one (31-07-2014)“…KCNQ potassium channels composed of KCNQ2 and KCNQ3 subunits give rise to the M-current, a slow-activating and non-inactivating voltage-dependent potassium…”
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Reduced axonal surface expression and phosphoinositide sensitivity in K v 7 channels disrupts their function to inhibit neuronal excitability in Kcnq2 epileptic encephalopathy
Published in Neurobiology of disease (01-10-2018)“…Neuronal K 7/KCNQ channels are voltage-gated potassium channels composed of K 7.2/KCNQ2 and K 7.3/KCNQ3 subunits. Enriched at the axonal membrane, they…”
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5
Regulation of STEP61 and tyrosine-phosphorylation of NMDA and AMPA receptors during homeostatic synaptic plasticity
Published in Molecular brain (22-09-2015)“…Sustained changes in network activity cause homeostatic synaptic plasticity in part by altering the postsynaptic accumulation of N-methyl-D-aspartate receptors…”
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