Search Results - "Cavanaugh, John M"

Neuronal Injury and Glial Changes Are Hallmarks of Open Field Blast Exposure in Swine Frontal Lobe by Kallakuri, Srinivasu, Desai, Alok, Feng, Ke, Tummala, Sharvani, Saif, Tal, Chen, Chaoyang, Zhang, Liying, Cavanaugh, John M, King, Albert I

“…With the rapid increase in the number of blast induced traumatic brain injuries and associated neuropsychological consequences in veterans returning from the…”
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Quantitative relationship between axonal injury and mechanical response in a rodent head impact acceleration model by Li, Yan, Zhang, Liying, Kallakuri, Srinivasu, Zhou, Runzhou, Cavanaugh, John M

“…A modified Marmarou impact acceleration model was developed to study the mechanical responses induced by this model and their correlation to traumatic axonal…”
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Investigate the Variations of the Head and Brain Response in a Rodent Head Impact Acceleration Model by Finite Element Modeling by Zhou, Runzhou, Li, Yan, Cavanaugh, John M, Zhang, Liying

“…Diffuse axonal injury (DAI) is a severe form of traumatic brain injury and often induced by blunt trauma. The closed head impact acceleration (IA) model is the…”
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Effects of interleukin-1 beta, interleukin-6, and tumor necrosis factor on sensitivity of dorsal root ganglion and peripheral receptive fields in rats by Ozaktay, A Cüneyt, Kallakuri, Srinivasu, Takebayashi, Tsuneo, Cavanaugh, John M, Asik, Ibrahim, DeLeo, Joyce A, Weinstein, James N

“…This study was designed to characterize the effects of low doses (0.5-5 ng) of pro-inflammatory cytokines, interleukin-1 beta (IL-1beta), interleukin-6 (IL-6),…”
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Temporal assessment of traumatic axonal injury in the rat corpus callosum and optic chiasm by Zakaria, Nisrine, Kallakuri, Srinivasu, Bandaru, Sharath, Cavanaugh, John M

“…Abstract Impaired axoplasmic transport (IAT) and neurofilament compaction (NFC), two common axonal pathology processes involved in traumatic axonal injury…”
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Mechanical properties of spinal nerve roots subjected to tension at different strain rates by Singh, Anita, Lu, Ying, Chen, Chaoyang, M Cavanaugh, John

“…An understanding of the biomechanical and physiological properties of spinal nerve roots, particularly in response to tension, is critical in understanding the…”
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Impaired axoplasmic transport is the dominant injury induced by an impact acceleration injury device: An analysis of traumatic axonal injury in pyramidal tract and corpus callosum of rats by Kallakuri, Srinivasu, Li, Yan, Zhou, Runzhou, Bandaru, Sharath, Zakaria, Nisrine, Zhang, Liying, Cavanaugh, John M

“…Abstract Traumatic axonal injury (TAI) involves neurofilament compaction (NFC) and impaired axoplasmic transport (IAT) in distinct populations of axons…”
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Demonstration of substance P, calcitonin gene-related peptide, and protein gene product 9.5 containing nerve fibers in human cervical facet joint capsules by KALLAKURI, Srinivasu, SINGH, Anita, CHAOYANG CHEN, CAVANAUGH, John M

“…Human cervical facet joint capsules were evaluated by immunohistochemistry. To study the neuropeptide innervation of the cadaveric cervical facet joint…”
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An evaluation of three-dimensional image–guided technologies in percutaneous pelvic and acetabular lag screw placement by Xu, Peng, MD, Wang, Hua, MD, Liu, Zhi-yong, MS, Mu, Wei-dong, MD, Xu, Shi-hong, MD, Wang, Lu-bo, MD, Chen, Chaoyang, MD, Cavanaugh, John M., MD

“…Abstract Background Percutaneous stabilization using three-dimensional (3D) navigation system is a promising treatment for pelvic and acetabular fractures…”
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Magnetic resonance imaging-based relationships between neck muscle cross-sectional area and neck circumference for adults and children by Dawson, Renée M., Latif, Zahid, Haacke, E. Mark, Cavanaugh, John M.

“…Background Computer models and human surrogates used to study the forces and motion of the human neck under various loading conditions are based solely on…”
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Mechanical strain to maxillary incisors during direct laryngoscopy by Engoren, Milo, Rochlen, Lauryn R, Diehl, Matthew V, Sherman, Sarah S, Jewell, Elizabeth, Golinski, Mary, Begeman, Paul, Cavanaugh, John M

“…While most Direct laryngoscopy leads to dental injury in 25-39% of cases. Dental injury occurs when the forces and impacts applied to the teeth exceed the…”
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Effect of nucleus pulposus on the neural activity of dorsal root ganglion by TAKEBAYASHI, Tsuneo, CAVANAUGH, John M, OZAKTAY, A. Cüneyt, KALLAKURI, Srinivasu, CHEN, Chaoyang

“…This study was designed to investigate, using neurophysiologic techniques in an in vivo rat model, the effect of application of nucleus pulposus to the nerve…”
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Effects of nucleus pulposus on nerve root neural activity, mechanosensitivity, axonal morphology, and sodium channel expression by CHAOYANG CHEN, CAVANAUGH, John M, ZHENG SONG, TAKEBAYASHI, Tsuneo, KALLAKURI, Srinivasu, WOOLEY, Paul H

“…This study analyzed the effects of autografted nucleus pulposus on nerve root axon morphology, neurophysiologic function, and sodium channel expression. To…”
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Pain generation in lumbar and cervical facet joints by Cavanaugh, John M, Lu, Ying, Chen, Chaoyang, Kallakuri, Srinivasu

“…Facet joints are implicated as a major source of neck and low-back pain. Both cervical and lumbar facet syndromes have been described in the medical…”
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Dynamic Response of the Thoracolumbar and Sacral Spine to Simulated Underbody Blast Loading in Whole Body Post Mortem Human Subject Tests by Sherman, Donald, Somasundaram, Karthik, Begeman, Paul, Foley, Sierra, Greb, Jason, Bir, Cynthia, Demetropoulos, Constantine K., Cavanaugh, John M.

“…Fourteen simulated underbody blast impact sled tests were performed using a horizontal deceleration sled with the aim of evaluating the dynamic response of the…”
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Recording of neural activity from goat cervical facet joint capsule using custom-designed miniature electrodes by CHAOYANG CHEN, YING LU, CAVANAUGH, John M, KALLAKURI, Srinivasu, PATWARDHAN, Ajit

“…To establish a methodology for the neurophysiologic study of mechanoreceptors in the cervical facet joint capsule. To test a custom designed miniature dual…”
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Correlation of mechanical impact responses and biomarker levels: A new model for biomarker evaluation in TBI by Li, Yan, Zhang, Liying, Kallakuri, Srinivasu, Cohen, Abigail, Cavanaugh, John M

“…Abstract A modified Marmarou impact acceleration model was used to help screen biomarkers to assess brain injury severity. Anesthetized male Sprague–Dawley…”
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Whole Body PMHS Response in Injurious Experimental Accelerative Loading Events by Rupp, Jonathan D., Zaseck, Lauren, Miller, Carl S., Bonifas, Anne C., Reed, Matthew P., Sherman, Don, Cavanaugh, John M., Ott, Kyle, Demetropoulos, Constantine K.

“…Previous studies involving whole-body post-mortem human surrogates (PHMS) have generated biomechanical response specifications for physically simulated…”
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Lumbar facet pain: Biomechanics, neuroanatomy and neurophysiology by Cavanaugh, John M., Ozaktay, A.Cuneyt, Yamashita, H.Toshihiko, King, Albert I.

“…Idiopathic low back pain has confounded health care practitioners for decades. Although there has been much advance in the understanding of the biomechanics of…”
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Spatial and temporal dynamics of HDACs class IIa following mild traumatic brain injury in adult rats by Kamal, Swatabdi R., Potukutchi, Shreya, Gelovani, David J., Bonomi, Robin E., Kallakuri, Srinivasu, Cavanaugh, John M., Mangner, Thomas, Conti, Alana, Liu, Ren-Shyan, Pasqualini, Renata, Arap, Wadih, Sidman, Richard L., Perrine, Shane A., Gelovani, Juri G.

“…The fundamental role of epigenetic regulatory mechanisms involved in neuroplasticity and adaptive responses to traumatic brain injury (TBI) is gaining…”
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