Search Results - "Cavalli, G."
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Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy
Published in Nature (London) (14-09-2017)“…Human glioblastomas harbour a subpopulation of glioblastoma stem cells that drive tumorigenesis. However, the origin of intratumoural functional heterogeneity…”
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Widespread activation of developmental gene expression characterized by PRC1-dependent chromatin looping
Published in Science advances (10-01-2020)“…Polycomb repressive complexes 1 and 2 have been historically described as transcriptional repressors, but recent reports suggest that PRC1 might also support…”
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PRMT5 inhibition disrupts splicing and stemness in glioblastoma
Published in Nature communications (12-02-2021)“…Glioblastoma (GBM) is a deadly cancer in which cancer stem cells (CSCs) sustain tumor growth and contribute to therapeutic resistance. Protein arginine…”
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Transient loss of Polycomb components induces an epigenetic cancer fate
Published in Nature (London) (16-05-2024)“…Although cancer initiation and progression are generally associated with the accumulation of somatic mutations 1 , 2 , substantial epigenomic alterations…”
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Gender differences in clinical presentation and vascular pattern in patients with Takayasu arteritis
Published in Scandinavian journal of rheumatology (02-11-2019)“…Objective: To compare clinical characteristics and pattern of vascular involvement at disease onset according to gender specificity in patients with Takayasu…”
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A shear cell study on oral and inhalation grade lactose powders
Published in Powder technology (15-07-2020)“…Shear cell tests have been conducted on twenty different lactose powders, most of which commercially available for oral or inhalation purposes, spanning a wide…”
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VC-resist glioblastoma cell state: vessel co-option as a key driver of chemoradiation resistance
Published in Nature communications (29-04-2024)“…Glioblastoma (GBM) is a highly lethal type of cancer. GBM recurrence following chemoradiation is typically attributed to the regrowth of invasive and resistant…”
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Viral clearance after early corticosteroid treatment in patients with moderate or severe covid-19
Published in Scientific reports (04-12-2020)“…The aim of this study was to evaluate the impact of early treatment with corticosteroids on SARS-CoV-2 clearance in hospitalized COVID-19 patients…”
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Efficacy and safety of biological agents in adult-onset Still's disease
Published in Scandinavian journal of rheumatology (04-07-2015)“…Objectives: To describe the efficacy and safety of different biological agents in a large cohort of 20 patients with adult-onset Still's disease (AOSD)…”
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Is it hyperlexia? Toward a deeper understanding of precocious reading skills in two cases of children with Autism Spectrum Disorder
Published in Clinica terapeutica (07-02-2022)“…Hyperlexia is defined by a precocious and sponta-neously acquired ability to read at preschool age. Hyperlexia appears to be a wide yet not highly studied…”
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Myocarditis as a manifestation of Erdheim-Chester Disease: successful use of anti- IL1 and BRAF inhibitor combination therapy
Published in Scandinavian journal of rheumatology (04-05-2022)Get full text
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Integrated analysis of proteome, phosphotyrosine‐proteome, tyrosine‐kinome, and tyrosine‐phosphatome in acute myeloid leukemia
Published in Proteomics (Weinheim) (01-03-2017)“…Reversible protein‐tyrosine phosphorylation is catalyzed by the antagonistic actions of protein‐tyrosine kinases (PTKs) and phosphatases (PTPs), and represents…”
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Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters
Published in Science (American Association for the Advancement of Science) (10-08-2012)“…Through hyperacetylation of histone H4 lysine 16 (H4K16), the male-specific lethal (MSL) complex in Drosophila approximately doubles transcription from the…”
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Developmental determinants in non-communicable chronic diseases and ageing
Published in Thorax (01-06-2015)“…Prenatal and peri-natal events play a fundamental role in health, development of diseases and ageing (Developmental Origins of Health and Disease (DOHaD))…”
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An autocrine ActivinB mechanism drives TGFβ/Activin signaling in Group 3 medulloblastoma
Published in EMBO molecular medicine (01-08-2019)“…Medulloblastoma (MB) is a pediatric tumor of the cerebellum divided into four groups. Group 3 is of bad prognosis and remains poorly characterized. While the…”
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The MOF Chromobarrel Domain Controls Genome-wide H4K16 Acetylation and Spreading of the MSL Complex
Published in Developmental cell (13-03-2012)“…The histone H4 lysine 16 (H4K16)-specific acetyltransferase MOF is part of two distinct complexes involved in X chromosome dosage compensation and autosomal…”
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Nutrient availability and nutrient use efficiency in plants growing in the transition zone between land and water
Published in Plant biology (Stuttgart, Germany) (01-03-2016)“…The transition zone between terrestrial and freshwater habitats is highly dynamic, with large variability in environmental characteristics. Here, we…”
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Publisher Correction: Viral clearance after early corticosteroid treatment in patients with moderate or severe covid-19
Published in Scientific reports (17-05-2021)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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