Search Results - "Cavallari, Joseph F"

The efflux inhibitor phenylalanine-arginine beta-naphthylamide (PAβN) permeabilizes the outer membrane of gram-negative bacteria by Lamers, Ryan P, Cavallari, Joseph F, Burrows, Lori L

“…Active efflux of antimicrobial agents is a primary mechanism by which bacterial pathogens can become multidrug resistant. The combined use of efflux pump…”
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Metabolic endotoxemia is dictated by the type of lipopolysaccharide by Anhê, Fernando F., Barra, Nicole G., Cavallari, Joseph F., Henriksbo, Brandyn D., Schertzer, Jonathan D.

“…Lipopolysaccharides (LPSs) can promote metabolic endotoxemia, which is considered inflammatory and metabolically detrimental based on Toll-like receptor (TLR)4…”
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Muramyl Dipeptide-Based Postbiotics Mitigate Obesity-Induced Insulin Resistance via IRF4 by Cavallari, Joseph F., Fullerton, Morgan D., Duggan, Brittany M., Foley, Kevin P., Denou, Emmanuel, Smith, Brennan K., Desjardins, Eric M., Henriksbo, Brandyn D., Kim, Kalvin J., Tuinema, Brian R., Stearns, Jennifer C., Prescott, David, Rosenstiel, Philip, Coombes, Brian K., Steinberg, Gregory R., Schertzer, Jonathan D.

“…Intestinal dysbiosis contributes to obesity and insulin resistance, but intervening with antibiotics, prebiotics, or probiotics can be limited by specificity…”
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RIPK2 Dictates Insulin Responses to Tyrosine Kinase Inhibitors in Obese Male Mice by Duggan, Brittany M, Cavallari, Joseph F, Foley, Kevin P, Barra, Nicole G, Schertzer, Jonathan D

“…Abstract Tyrosine kinase inhibitors (TKIs) used in cancer are also being investigated in diabetes. TKIs can improve blood glucose control in diabetic cancer…”
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Fluvastatin causes NLRP3 inflammasome-mediated adipose insulin resistance by Henriksbo, Brandyn D, Lau, Trevor C, Cavallari, Joseph F, Denou, Emmanuel, Chi, Wendy, Lally, James S, Crane, Justin D, Duggan, Brittany M, Foley, Kevin P, Fullerton, Morgan D, Tarnopolsky, Mark A, Steinberg, Gregory R, Schertzer, Jonathan D

“…Statins reduce lipid levels and are widely prescribed. Statins have been associated with an increased incidence of type 2 diabetes, but the mechanisms are…”
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Bacterial peptidoglycan stimulates adipocyte lipolysis via NOD1 by Chi, Wendy, Dao, Dyda, Lau, Trevor C, Henriksbo, Brandyn D, Cavallari, Joseph F, Foley, Kevin P, Schertzer, Jonathan D

“…Obesity is associated with inflammation that can drive metabolic defects such as hyperlipidemia and insulin resistance. Specific metabolites can contribute to…”
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Tyrosine kinase inhibitors of Ripk2 attenuate bacterial cell wall-mediated lipolysis, inflammation and dysglycemia by Duggan, Brittany M., Foley, Kevin P., Henriksbo, Brandyn D., Cavallari, Joseph F., Tamrakar, Akhilesh K., Schertzer, Jonathan D.

“…Inflammation underpins aspects of insulin resistance and dysglycemia. Microbiota-derived cell wall components such as muropeptides or endotoxin can trigger…”
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Changes to Its Peptidoglycan-Remodeling Enzyme Repertoire Modulate β-Lactam Resistance in Pseudomonas aeruginosa by CAVALLARI, Joseph F, LAMERS, Ryan P, SCHEURWATER, Edie M, MATOS, Andrea L, BURROWS, Lori L

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Gut microbiota impairs insulin clearance in obese mice by Foley, Kevin P., Zlitni, Soumaya, Duggan, Brittany M., Barra, Nicole G., Anhê, Fernando F., Cavallari, Joseph F., Henriksbo, Brandyn D., Chen, Cassandra Y., Huang, Michael, Lau, Trevor C., Plante, Roxanne, Schwab, Michael, Marette, André, Schertzer, Jonathan D.

“…Hyperinsulinemia can be both a cause and consequence of obesity and insulin resistance. Hyperinsulinemia can result from increased insulin secretion and/or…”
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Intestinal Microbiota Contributes to Energy Balance, Metabolic Inflammation, and Insulin Resistance in Obesity by Cavallari, Joseph F, Schertzer, Jonathan D

“…Obesity is associated with increased risk of developing metabolic diseases such as type 2 diabetes. The origins of obesity are multi-factorial, but ultimately…”
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Micronutrients impact the gut microbiota and blood glucose by Barra, Nicole G, Anhê, Fernando F, Cavallari, Joseph F, Singh, Anita M, Chan, Darryl Y, Schertzer, Jonathan D

“…Micronutrients influence hormone action and host metabolism. Dietary minerals, trace elements, and vitamins can alter blood glucose and cellular glucose…”
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Statins Promote Interleukin-1β-Dependent Adipocyte Insulin Resistance Through Lower Prenylation, Not Cholesterol by Henriksbo, Brandyn D, Tamrakar, Akhilesh K, Xu, Joshua, Duggan, Brittany M, Cavallari, Joseph F, Phulka, Jobanjit, Stampfli, Martin R, Ashkar, Ali A, Schertzer, Jonathan D

“…Statins lower cholesterol and adverse cardiovascular outcomes, but this drug class increases diabetes risk. Statins are generally anti-inflammatory. However,…”
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Defective NOD2 peptidoglycan sensing promotes diet‐induced inflammation, dysbiosis, and insulin resistance by Denou, Emmanuel, Lolmède, Karine, Garidou, Lucile, Pomie, Celine, Chabo, Chantal, Lau, Trevor C, Fullerton, Morgan D, Nigro, Giulia, Zakaroff‐Girard, Alexia, Luche, Elodie, Garret, Céline, Serino, Matteo, Amar, Jacques, Courtney, Michael, Cavallari, Joseph F, Henriksbo, Brandyn D, Barra, Nicole G, Foley, Kevin P, McPhee, Joseph B, Duggan, Brittany M, O'Neill, Hayley M, Lee, Amanda J, Sansonetti, Philippe, Ashkar, Ali A, Khan, Waliul I, Surette, Michael G, Bouloumié, Anne, Steinberg, Gregory R, Burcelin, Rémy, Schertzer, Jonathan D

“…Pattern recognition receptors link metabolite and bacteria‐derived inflammation to insulin resistance during obesity. We demonstrate that NOD2 detection of…”
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Different Th17 immunity in gut, liver, and adipose tissues during obesity: the role of diet, genetics, and microbes by Cavallari, Joseph F., Denou, Emmanuel, Foley, Kevin P., Khan, Waliul I., Schertzer, Jonathan D.

“…Microbes modify immunometabolism responses linking obesity and type 2 diabetes. Immunity helps maintain a host-microbe symbiosis, but inflammation can promote…”
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2017-P: Gut Microbes after Bariatric Surgery in Humans Improve Glucose Control in Mice without Fat Loss by ANHÊ, FERNANDO FORATO, FOLEY, KEVIN P., BARRA, NICOLE G., DUGGAN, BRITTANY M., CAVALLARI, JOSEPH F., HENRIKSBO, BRANDYN D., CANI, PATRICE D., BIERTHO, LAURENT, TCHERNOF, ANDRE, MARETTE, ANDRE, SCHERTZER, JONATHAN D.

“…Bariatric surgery (BS) is the most efficacious treatment against severe obesity and T2D. Among bariatric procedures, biliopancreatic diversion with duodenal…”
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2036-P: Gut Microbes Regulate Insulin Clearance in Mice by FOLEY, KEVIN P., ZLITNI, SOUMAYA, DUGGAN, BRITTANY M., HENRIKSBO, BRANDYN D., BARRA, NICOLE G., CAVALLARI, JOSEPH F., ANHÊ, FERNANDO FORATO, LAU, TREVOR, CHEN, YUK KWAN, SCHERTZER, JONATHAN D.

“…Obesity and insulin resistance are associated with hyperinsulinemia, which is caused by increased insulin secretion and/or reduced insulin clearance. Impaired…”
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Targeting macrophage scavenger receptor 1 promotes insulin resistance in obese male mice by Cavallari, Joseph F., Anhê, Fernando F., Foley, Kevin P., Denou, Emmanuel, Chan, Rebecca W., Bowdish, Dawn M. E., Schertzer, Jonathan D.

“…Immune components can bridge inflammatory triggers to metabolic dysfunction. Scavenger receptors sense lipoproteins, but it is not clear how different…”
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22 by Cavallari, Joseph F., Fullerton, Morgan D., Denou, Emmanuel, Foley, Kevin P., Henriksbo, Brandyn D., Lau, Trevor C., Schertzer, Jonathan D.

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22: NOD2 immunity protects against obesity-induced inflammation and insulin resistance by Cavallari, Joseph F., Fullerton, Morgan D., Denou, Emmanuel, Foley, Kevin P., Henriksbo, Brandyn D., Lau, Trevor C., Schertzer, Jonathan D.

“…Obesity is associated with immune cell infiltration and inflammation in metabolic tissues that contributes to insulin resistance. Pattern recognition receptors…”
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The Efflux Inhibitor Phenylalanine-Arginine Beta-Naphthylamide (PA beta N) Permeabilizes the Outer Membrane of Gram-Negative Bacteria. e60666 by Lamers, Ryan P, Cavallari, Joseph F, Burrows, Lori L

“…Active efflux of antimicrobial agents is a primary mechanism by which bacterial pathogens can become multidrug resistant. The combined use of efflux pump…”
Get full text