Search Results - "Cavalier, Alyssa N"

Amyloid beta acts synergistically as a pro-inflammatory cytokine by LaRocca, Thomas J., Cavalier, Alyssa N., Roberts, Christine M., Lemieux, Maddie R., Ramesh, Pooja, Garcia, Micklaus A., Link, Christopher D.

“…The amyloid beta (Aβ) peptide is believed to play a central role in Alzheimer's disease (AD), the most common age-related neurodegenerative disorder. However,…”
Get full text

ADAR1 suppression causes interferon signaling and transposable element transcript accumulation in human astrocytes by McEntee, Cali M, Cavalier, Alyssa N, LaRocca, Thomas J

“…Neuroinflammation is a central mechanism of brain aging and Alzheimer's disease (AD), but the exact causes of age- and AD-related neuroinflammation are…”
Get full text

Letter to the Editor: Cancer Perceptions Among Smokeless Tobacco Users: A Qualitative Study of US Firefighters by Gao, Xiang, Deming, Nathan J., Cavalier, Alyssa N.

“…KCI Citation Count: 0…”
Get full text

Letter to the Editor: Cancer Perceptions Among Smokeless Tobacco Users: A Qualitative Study of US Firefighters by Gao, Xiang, Deming, Nathan J, Cavalier, Alyssa N

Get full text

Repetitive elements as a transcriptomic marker of aging: Evidence in multiple datasets and models by LaRocca, Thomas J., Cavalier, Alyssa N., Wahl, Devin

“…Transcriptomic markers of aging can be useful for studying age‐related processes and diseases. However, noncoding repetitive element (RE) transcripts, which…”
Get full text

Novel Strategies for Healthy Brain Aging by Wahl, Devin, Cavalier, Alyssa N., LaRocca, Thomas J.

“…One of the best strategies for healthy brain aging is regular aerobic exercise. Commonly studied “anti-aging” compounds may mimic some effects of exercise on…”
Get full text

ADAR Dysfunction in Brain Aging and Alzheimer's Disease by McEntee, Cali M., Cavalier, Alyssa N., LaRocca, Thomas J.

“…Neuroinflammation is a central mechanism of brain aging and neurodegenerative disease, but why neuroinflammation develops with aging is incompletely…”
Get full text

Healthy Aging Interventions Reduce Repetitive Element Transcripts by Wahl, Devin, Cavalier, Alyssa N, Smith, Meghan, Seals, Douglas R, LaRocca, Thomas J

“…Abstract Transcripts from noncoding repetitive elements (REs) in the genome may be involved in aging. However, they are often ignored in transcriptome studies…”
Get full text

Pigmented and Dunkin‐Hartley Guinea Pigs as Natural Models for Brain Aging and Alzheimer’s Disease by Wahl, Devin, Moreno, Julie, Santangelo, Kelly, Cavalier, Alyssa N., Hamilton, Karyn L., LaRocca, Thomas J.

“…Aging is the primary risk factor for most chronic diseases, including Alzheimer’s disease (AD). Current pre‐clinical approaches for studying brain aging and AD…”
Get full text

Contribution of the Microbiome to Western Diet‐Induced Gene Expression Changes in the Intestine and Vasculature by Cavalier, Alyssa N., Weir, Tiffany L., Gentile, Christopher L., LaRocca, Thomas J.

“…Western diet (high fat/sugar) is a core contributor to obesity, which is associated with increased risk for chronic diseases, including cardiovascular disease…”
Get full text

Protective effects of apigenin on the brain transcriptome with aging by Cavalier, Alyssa N, Clayton, Zachary S, Wahl, Devin, Hutton, David A, McEntee, Cali M, Seals, Douglas R, LaRocca, Thomas J

“…Brain aging is associated with reduced cognitive function that increases the risk for dementia. Apigenin is a bioactive plant compound that inhibits cellular…”
Get full text

Cerebrovascular reactivity: a new frontier for measuring cognitive health in models of accelerated ageing? by Hutton, David A., Cavalier, Alyssa N., Clayton, Zachary S.

Get full text

The reverse transcriptase inhibitor 3TC protects against age‐related cognitive dysfunction by Wahl, Devin, Smith, Meghan E., McEntee, Cali M., Cavalier, Alyssa N., Osburn, Shelby C., Burke, Samuel D., Grant, Randy A., Nerguizian, David, Lark, Daniel S., Link, Christopher D., LaRocca, Thomas J.

“…Aging is the primary risk factor for most neurodegenerative diseases, including Alzheimer's disease. Major hallmarks of brain aging include…”
Get full text

Repetitive Element Transcripts are Associated with Inflammation in Older Adults by Smith, Meghan E., Cavalier, Alyssa N., McEntee, Cali M., Wahl, Devin, McWilliams, Gabriella T., Seals, Douglas R., LaRocca, Thomas J.

“…Growing evidence shows that expression of non‐coding repetitive sequences, or repetitive element (RE) transcripts, increases with age and may be related to…”
Get full text

Nontransgenic Guinea Pig Strains Exhibit Hallmarks of Human Brain Aging and Alzheimer’s Disease by Wahl, Devin, Moreno, Julie A, Santangelo, Kelly S, Zhang, Qian, Afzali, Maryam F, Walsh, Maureen A, Musci, Robert V, Cavalier, Alyssa N, Hamilton, Karyn L, LaRocca, Thomas J

“…Abstract Older age is the primary risk factor for most chronic diseases, including Alzheimer’s disease (AD). Current preclinical models to study brain aging…”
Get full text

Accelerated aging of the brain transcriptome by the common chemotherapeutic doxorubicin by Cavalier, Alyssa N., Clayton, Zachary S., Hutton, David A., Wahl, Devin, Lark, Daniel S., Reisz, Julie A., Melov, Simon, Campisi, Judith, Seals, Douglas R., LaRocca, Thomas J.

“…Cancer is one of the most common age-related diseases, and over one-third of cancer patients will receive chemotherapy. One frequently reported side effect of…”
Get full text

Repetitive element transcript accumulation is associated with inflammaging in humans by Smith, Meghan E., Wahl, Devin, Cavalier, Alyssa N., McWilliams, Gabriella T., Rossman, Matthew J., Giordano, Gregory R., Bryan, Angela D., Seals, Douglas R., LaRocca, Thomas J.

“…Chronic, low-grade inflammation increases with aging, contributing to functional declines and diseases that reduce healthspan. Growing evidence suggests that…”
Get full text

Response by Wahl, Devin, Cavalier, Alyssa N., LaRocca, Thomas J.

Get full text

Response by Wahl, Devin, Cavalier, Alyssa N., LaRocca, Thomas J.

Get full text

Response by Wahl, Devin, Cavalier, Alyssa N., LaRocca, Thomas J.

Get full text