Search Results - "Cavalcante Duarte, Marcelo"
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Microemulsions formed by PPG-5-CETETH-20 at low concentrations for transdermal delivery of nifedipine: Structural and in vitro study
Published in Colloids and surfaces, B, Biointerfaces (01-06-2022)“…Nifedipine is a potent anti-hypertensive, which is poorly orally bioavailable on account of first-pass metabolism, short half-life, and low water solubility…”
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Chemical Characterization, Antioxidant Activity and Cytotoxicity of the Unconventional Food Plants: Sweet Potato (Ipomoea batatas (L.) Lam.) Leaf, Major Gomes (Talinum paniculatum (Jacq.) Gaertn.) and Caruru (Amaranthus deflexus L.)
Published in Waste and biomass valorization (01-05-2021)“…Unconventional food plants (UFPs), many of them popularly known as "weeds", are edible species with nutritional and socioeconomic potential that need to be…”
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Phytochemical screening and cardiovascular effects of the ethanol extract of Erythroxylum passerinum mart
Published in Natural product research (01-02-2022)“…Species of genus are popularly used as anti-inflammatories and in the treatment of renal and respiratory disorders. Although it has been reported that species…”
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A Systematic Review for Anti-Inflammatory Property of Clusiaceae Family: A Preclinical Approach
Published in Evidence-based complementary and alternative medicine (01-01-2014)“…Background. Clusiaceae family (sensu lato) is extensively used in ethnomedicine for treating a number of disease conditions which include cancer, inflammation,…”
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HPLC-DAD-UV analysis, anti-inflammatory and anti-neuropathic effects of methanolic extract of Sideritis bilgeriana (lamiaceae) by NF-κB, TNF-α, IL-1β and IL-6 involvement
Published in Journal of ethnopharmacology (30-01-2021)“…Medicinal plants remain an invaluable source for therapeutics of diseases that affect humanity. Sideritis bilgeriana (Lamiaceae) is medicinal plant used in…”
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Development of morin/hydroxypropyl-β-cyclodextrin inclusion complex: Enhancement of bioavailability, antihyperalgesic and anti-inflammatory effects
Published in Food and chemical toxicology (01-04-2019)“…Morin is a flavonoid has been reported with several pharmacological effects such as, antioxidant, anti-inflammatory, anticancer, antidiabetic, etc. However,…”
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Eplingiella fruticosa leaf essential oil complexed with β-cyclodextrin exerts a neuroprotective effect in an Alzheimer’s disease animal model induced by Streptozotocin
Published in Metabolic brain disease (23-11-2024)“…Alzheimer’s Disease (AD) is physiopathologically marked by an accumulation of beta-amyloid peptide (Aβ), hyperphosphorylation of tau protein, inflammation, and…”
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Lyotropic liquid crystal mesophases as transdermal delivery systems for lipophilic drugs: A comparative study
Published in International journal of pharmaceutics (05-04-2023)“…[Display omitted] The present work aimed to evaluate different Liquid Crystal Mesophases (LCM) as transdermal drug delivery systems (TDDS) for nifedipine…”
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Enhancing orofacial pain relief: α-phellandrene complexed with hydroxypropyl-β-cyclodextrin mitigates orofacial nociception in rodents
Published in Naunyn-Schmiedeberg's archives of pharmacology (04-11-2024)“…Orofacial pain affects 10-15% of adults and can severely impact quality of life. Despite ongoing treatment challenges, monoterpene alpha-phellandrene (PHE)…”
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Dereplication and quantification of the ethanol extract of Miconia albicans (Melastomaceae) by HPLC-DAD-ESI-/MS/MS, and assessment of its anti-hyperalgesic and anti-inflammatory profiles in a mice arthritis-like model: Evidence for involvement of TNF-α, IL-1β and IL-6
Published in Journal of ethnopharmacology (10-08-2020)“…Miconia albicans (Sw) Triana (Melastomataceae), a medicinal plant widely used by practitioners of folk medicine in the northeast of Brazil, has been used to…”
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Eplingiella fruticosa (Lamiaceae) essential oil complexed with β-cyclodextrin improves its anti-hyperalgesic effect in a chronic widespread non-inflammatory muscle pain animal model
Published in Food and chemical toxicology (01-01-2020)“…Eplingiella fruticosa (Lamiaceae), formally known as Hyptis fruticosa, is an important aromatic medicinal herb used in folk medicine in northeastern Brazil. We…”
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The ethanol extract of Leonurus sibiricus L. induces antioxidant, antinociceptive and topical anti-inflammatory effects
Published in Journal of ethnopharmacology (12-07-2017)“…Leonurus sibiricus L. (Lamiaceae), popularly known as motherwort, or “erva-de-macaé” or “rubim” in Brazil, is a plant used for the treatment of inflammatory…”
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Structure–Activity Relationship of Terpenes with Anti‐Inflammatory Profile – A Systematic Review
Published in Basic & clinical pharmacology & toxicology (01-09-2014)“…Inflammation is a complex biological response that in spite of having available treatments, their side effects limit their usefulness. Because of this, natural…”
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Evaluation of the acute toxicity and antidiabetic activity of Coutoubea spicata “nicolau” ethanolic extract and ethyl acetate fraction
Published in Boletín latinoamericano y del Caribe de plantas medicinales y aromáticas (01-09-2023)“…In order to understand antidiabetic potential and toxicity, this study aimed to evaluate the acute toxicity and antidiabetic activity of ethanolic extract and…”
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Essential oil from fruit of Xylopia langsdorffiana: antitumour activity and toxicity
Published in Pharmaceutical biology (01-12-2016)“…Context: The genus Xylopia L. (Annonaceae) includes aromatic plants that have both nutritional and medicinal uses. Essential oils of Xylopia species have…”
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Maytensifolone, a New Triterpene from Maytenus distichophylla Mart. ex Reissek
Published in Journal of the Brazilian Chemical Society (01-10-2013)“…Phytochemical study of the leaves of Maytenus distichophylla Mart. ex Reissek led to the isolation of the new triterpene…”
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Phytochemical screening and cardiovascular effects of the ethanol extract of Erythroxylum passerinum mart
Published in Natural Product Research (16-02-2022)“…Species of Erythroxylum genus are popularly used as anti-inflammatories and in the treatment of renal and respiratory disorders. Although it has been reported…”
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