Search Results - "Cavaglieri, Rita C."
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Apelin retards the progression of diabetic nephropathy
Published in American journal of physiology. Renal physiology (15-03-2013)“…Apelin and its receptor APJ have pleiotropic effects in mice and humans and play a protective role in cardiovascular diseases at least partially by inhibiting…”
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2
Hydrogen Sulfide Inhibits High Glucose-induced Matrix Protein Synthesis by Activating AMP-activated Protein Kinase in Renal Epithelial Cells
Published in The Journal of biological chemistry (10-02-2012)“…Hydrogen sulfide, a signaling gas, affects several cell functions. We hypothesized that hydrogen sulfide modulates high glucose (30 mm) stimulation of matrix…”
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3
Targeting NADPH oxidase with a novel dual Nox1/Nox4 inhibitor attenuates renal pathology in type 1 diabetes
Published in American journal of physiology. Renal physiology (01-06-2015)“…Reactive oxygen species (ROS) generated by Nox NADPH oxidases may play a critical role in the pathogenesis of diabetic nephropathy (DN). The efficacy of the…”
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Metformin prevents renal interstitial fibrosis in mice with unilateral ureteral obstruction
Published in Molecular and cellular endocrinology (05-09-2015)“…•Metformin ameliorates inflammation and interstitial fibrosis in obstructed kidneys.•AMPK activity is not reduced in obstructed kidneys.•Activation of AMPK by…”
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Antifibrotic Effect of Tamoxifen in a Model of Progressive Renal Disease
Published in Journal of the American Society of Nephrology (01-01-2012)“…Tamoxifen, a selective estrogen receptor modulator, has antifibrotic properties; however, whether it can attenuate renal fibrosis is unknown. In this study, we…”
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