Search Results - "Cavadini, E"

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    PLAB induction in fenretinide-induced apoptosis of ovarian cancer cells occurs via a ROS-dependent mechanism involving ER stress and JNK activation by Appierto, Valentina, Tiberio, Paola, Villani, Maria Grazia, Cavadini, Elena, Formelli, Franca

    Published in Carcinogenesis (New York) (01-05-2009)
    “…Fenretinide [N-(4-hydroxyphenyl)-retinamide (4HPR)] is a synthetic retinoid with antitumor activity that induces apoptosis in various types of cancer cell. We…”
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    Journal Article
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    Analysis of gene expression identifies PLAB as a mediator of the apoptotic activity of fenretinide in human ovarian cancer cells by APPIERTO, V, VILLANI, M. G, FORMELLI, F, CAVADINI, E, GARIBOLDI, M, DE CECCO, L, PIEROTTI, M. A, LAMBERT, J. R, REID, J, TIBERIO, P, COLOMBO, N

    Published in Oncogene (07-06-2007)
    “…Fenretinide (4-HPR) is a synthetic retinoid with antitumor activity, which induces apoptosis in cancer cell lines of different histotypes. To identify genes…”
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    Journal Article
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    Involvement of c-Fos in fenretinide-induced apoptosis in human ovarian carcinoma cells by Appierto, V, Villani, M G, Cavadini, E, Lotan, R, Vinson, C, Formelli, F

    Published in Cell death and differentiation (01-03-2004)
    “…Fenretinide (HPR), a synthetic retinoid that exhibits lower toxicity than other retinoids, has shown preventive and therapeutic activity against ovarian…”
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    Journal Article
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    Decrease in drug accumulation and in tumour aggressiveness marker expression in a fenretinide-induced resistant ovarian tumour cell line by APPIERTO, V, CAVADINI, E, PERGOLIZZI, R, CLERIS, L, LOTAN, R, CANEVARI, S, FORMELLI, F

    Published in British journal of cancer (01-06-2001)
    “…We investigated whether the efficacy of fenretinide (HPR) against ovarian tumours may be limited by induction of resistance. The human ovarian carcinoma cell…”
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    Journal Article
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    Pharmacokinetics and effects on plasma retinol concentrations of 13-cis-retinoic acid in melanoma patients by FORMELLI, F, CAVADINI, E, MASCHERONI, L, BELLI, F, CASCINELLI, N

    Published in British journal of cancer (1997)
    “…The pharmacokinetics of 13-cis-retinoic acid (13cisRA) and its effects on retinol plasma levels were investigated after the first and the last doses in…”
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    Phase I Trial and Pharmacokinetics of Fenretinide in Children with Neuroblastoma by GARAVENTA, Alberto, LUKSCH, Roberto, BELLANI, Franca Fossati, FORMELLI, Franca, LO PICCOLO, Maria Serena, CAVADINI, Elena, MONTALDO, Paolo G, PIZZITOLA, Maria Rosa, BONI, Luca, PONZONI, Mirco, DECENSI, Andrea, DE BERNARDI, Bruno

    Published in Clinical cancer research (01-06-2003)
    “…Purpose: Fenretinide (4HPR), a synthetic retinoid, induces apoptosis in neuroblastoma cells. A Phase I study in children with neuroblastoma was designed to…”
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    Altered sphingolipid metabolism in N-(4-hydroxyphenyl)-retinamide-resistant A2780 human ovarian carcinoma cells by Prinetti, Alessandro, Basso, Luisa, Appierto, Valentina, Villani, Maria Grazia, Valsecchi, Manuela, Loberto, Nicoletta, Prioni, Simona, Chigorno, Vanna, Cavadini, Elena, Formelli, Franca, Sonnino, Sandro

    Published in The Journal of biological chemistry (21-02-2003)
    “…In the present work, we studied the effects of fenretinide (N-(4-hydroxyphenyl)retinamide (HPR)), a hydroxyphenyl derivative of all-trans-retinoic acid, on…”
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    Journal Article
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    Identification of the Fenretinide Metabolite 4-Oxo-Fenretinide Present in Human Plasma and Formed in Human Ovarian Carcinoma Cells through Induction of Cytochrome P450 26A1 by VILLANI, Maria Grazia, APPIERTO, Valentina, CAVADINI, Elena, VALSECCHI, Manuela, SONNINO, Sandro, CURLEY, Robert W, FORNLELLI, Franca

    Published in Clinical cancer research (15-09-2004)
    “…Purpose: The synthetic retinoid fenretinide (4-HPR) exhibits preventive and therapeutic activity against ovarian tumors. An unidentified polar metabolite was…”
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    Role of retinoic acid receptor overexpression in sensitivity to fenretinide and tumorigenicity of human ovarian carcinoma cells by Pergolizzi, Rossana, Appierto, Valentina, Crosti, Mariacristina, Cavadini, Elena, Cleris, Loredana, Guffanti, Alessandro, Formelli, Franca

    Published in International journal of cancer (31-05-1999)
    “…The role of retinoic acid receptor (RAR) expression in sensitivity to N‐(4‐hydroxyphenyl)retinamide (4HPR or fenretinide) as well as on the tumorigenicity of…”
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    Fenretinide breast cancer prevention trial: drug and retinol plasma levels in relation to age and disease outcome by Formelli, Franca, Camerini, Tiziana, Cavadini, Elena, Appierto, Valentina, Villani, Maria Grazia, Costa, Alberto, De Palo, Giuseppe, Di Mauro, Maria Gaetana, Veronesi, Umberto

    “…To assess, in women participating in a breast cancer prevention trialon fenretinide (4-HPR), the relationship of drug and retinol levels with the risk of…”
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    Decrease in drug accumulation and in tumour aggressiveness marker expression in a fenretinide-induced resistant ovarianumour cell line by Appierto, V, Cavadini, E, Pergolizzi, R, Cleris, L, Lotan, R, Canevari, S, Formelli, F

    Published in British journal of cancer (01-06-2001)
    “…We investigated whether the efficacy of fenretinide (HPR) against ovarian tumours may be limited by induction of resistance. The human ovarian carcinoma cell…”
    Get full text
    Journal Article
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