Search Results - "Cavadini, E"
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PLAB induction in fenretinide-induced apoptosis of ovarian cancer cells occurs via a ROS-dependent mechanism involving ER stress and JNK activation
Published in Carcinogenesis (New York) (01-05-2009)“…Fenretinide [N-(4-hydroxyphenyl)-retinamide (4HPR)] is a synthetic retinoid with antitumor activity that induces apoptosis in various types of cancer cell. We…”
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1026 AF1q – a Novel Mediator of Basal and 4-HPR-Induced Apoptosis in Ovarian Cancer Cells
Published in European journal of cancer (1990) (01-07-2012)Get full text
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Analysis of gene expression identifies PLAB as a mediator of the apoptotic activity of fenretinide in human ovarian cancer cells
Published in Oncogene (07-06-2007)“…Fenretinide (4-HPR) is a synthetic retinoid with antitumor activity, which induces apoptosis in cancer cell lines of different histotypes. To identify genes…”
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Involvement of c-Fos in fenretinide-induced apoptosis in human ovarian carcinoma cells
Published in Cell death and differentiation (01-03-2004)“…Fenretinide (HPR), a synthetic retinoid that exhibits lower toxicity than other retinoids, has shown preventive and therapeutic activity against ovarian…”
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Decrease in drug accumulation and in tumour aggressiveness marker expression in a fenretinide-induced resistant ovarian tumour cell line
Published in British journal of cancer (01-06-2001)“…We investigated whether the efficacy of fenretinide (HPR) against ovarian tumours may be limited by induction of resistance. The human ovarian carcinoma cell…”
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Pharmacokinetics and effects on plasma retinol concentrations of 13-cis-retinoic acid in melanoma patients
Published in British journal of cancer (1997)“…The pharmacokinetics of 13-cis-retinoic acid (13cisRA) and its effects on retinol plasma levels were investigated after the first and the last doses in…”
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Phase I Trial and Pharmacokinetics of Fenretinide in Children with Neuroblastoma
Published in Clinical cancer research (01-06-2003)“…Purpose: Fenretinide (4HPR), a synthetic retinoid, induces apoptosis in neuroblastoma cells. A Phase I study in children with neuroblastoma was designed to…”
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Randomized trial of fenretinide (4‐HPR) to prevent recurrences, new localizations and carcinomas in patients operated on for oral leukoplakia: Long‐term results
Published in International journal of cancer (01-07-2005)“…We assessed the efficacy of fenretinide at preventing relapses, new lesions and carcinomas after surgical excision of oral leukoplakia. In a controlled…”
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Altered sphingolipid metabolism in N-(4-hydroxyphenyl)-retinamide-resistant A2780 human ovarian carcinoma cells
Published in The Journal of biological chemistry (21-02-2003)“…In the present work, we studied the effects of fenretinide (N-(4-hydroxyphenyl)retinamide (HPR)), a hydroxyphenyl derivative of all-trans-retinoic acid, on…”
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Identification of the Fenretinide Metabolite 4-Oxo-Fenretinide Present in Human Plasma and Formed in Human Ovarian Carcinoma Cells through Induction of Cytochrome P450 26A1
Published in Clinical cancer research (15-09-2004)“…Purpose: The synthetic retinoid fenretinide (4-HPR) exhibits preventive and therapeutic activity against ovarian tumors. An unidentified polar metabolite was…”
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Relationships between Plasma Insulin-like Growth Factor-I and Insulin-like Growth Factor Binding Protein-3 and Second Breast Cancer Risk in a Prevention Trial of Fenretinide
Published in Clinical cancer research (15-10-2003)“…Purpose : High circulating insulin-like growth factor (IGF) -I and/or low IGF-binding protein (IGFBP) -3 levels are associated with increased breast cancer…”
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Role of retinoic acid receptor overexpression in sensitivity to fenretinide and tumorigenicity of human ovarian carcinoma cells
Published in International journal of cancer (31-05-1999)“…The role of retinoic acid receptor (RAR) expression in sensitivity to N‐(4‐hydroxyphenyl)retinamide (4HPR or fenretinide) as well as on the tumorigenicity of…”
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Fenretinide breast cancer prevention trial: drug and retinol plasma levels in relation to age and disease outcome
Published in Cancer epidemiology, biomarkers & prevention (01-01-2003)“…To assess, in women participating in a breast cancer prevention trialon fenretinide (4-HPR), the relationship of drug and retinol levels with the risk of…”
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Long-Term Effects of Fenretinide, a Retinoic Acid Derivative, on the Insulin-like Growth Factor System in Women with Early Breast Cancer
Published in Cancer epidemiology, biomarkers & prevention (01-10-2001)“…High insulin-like growth factor-I (IGF-I) levels are associated with an increased risk of breast cancer in premenopausal women. Because the synthetic retinoid…”
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Decrease in drug accumulation and in tumour aggressiveness marker expression in a fenretinide-induced resistant ovarianumour cell line
Published in British journal of cancer (01-06-2001)“…We investigated whether the efficacy of fenretinide (HPR) against ovarian tumours may be limited by induction of resistance. The human ovarian carcinoma cell…”
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16
A distal cantilever bridge design
Published in Dental digest (01-07-1971)Get more information
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Design for partial bridge to replace several missing anterior teeth
Published in Dental digest (01-05-1968)Get more information
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Immediate bite-opening treatment partial for replacing anterior teeth in preparation for permanent partial restoration
Published in Dental digest (01-05-1967)Get more information
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Aids in establishing occlusal vertical dimension in denture construction
Published in Dental digest (01-07-1967)Get more information
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The value of the occlusal key in maxillary full denture relining technique
Published in Dental digest (01-06-1967)Get more information
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