Search Results - "Causse, Sébastien Z"
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Imaging transcription in living cells
Published in Annual review of biophysics (01-01-2009)“…The advent of new technologies for the imaging of living cells has made it possible to determine the properties of transcription, the kinetics of polymerase…”
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High-Frequency Promoter Firing Links THO Complex Function to Heavy Chromatin Formation
Published in Cell reports (Cambridge) (27-11-2013)“…The THO complex is involved in transcription, genome stability, and messenger ribonucleoprotein (mRNP) formation, but its precise molecular function remains…”
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Gene Expression Is Circular: Factors for mRNA Degradation Also Foster mRNA Synthesis
Published in Cell (23-05-2013)“…Maintaining proper mRNA levels is a key aspect in the regulation of gene expression. The balance between mRNA synthesis and decay determines these levels. We…”
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Real-Time Dynamics of RNA Polymerase II Clustering in Live Human Cells
Published in Science (American Association for the Advancement of Science) (09-08-2013)“…Transcription is reported to be spatially compartmentalized in nuclear transcription factories with clusters of RNA polymerase II (Pol II). However, little is…”
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The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing
Published in PLoS biology (01-01-2011)“…RNA processing events that take place on the transcribed pre-mRNA include capping, splicing, editing, 3' processing, and polyadenylation. Most of these…”
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6
Lactobacillus stress protein GroEL prevents colonic inflammation
Published in Journal of gastroenterology (01-05-2021)“…Background We previously showed that supernatants of Lactobacillus biofilms induced an anti-inflammatory response by affecting the secretion of…”
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HSP110 translocates to the nucleus upon genotoxic chemotherapy and promotes DNA repair in colorectal cancer cells
Published in Oncogene (01-04-2019)“…A multicenter clinical study demonstrated the presence of a loss-of-function HSP110 mutation in about 15% of colorectal cancers, which resulted from an…”
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Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2
Published in Nature structural & molecular biology (01-09-2023)“…The inhibitor of apoptosis protein BIRC2 regulates fundamental cell death and survival signaling pathways. Here we show that BIRC2 accumulates in the nucleus…”
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