Search Results - "Caumes, Cécile"
-
1
The Click Triazolium Peptoid Side Chain: A Strong cis-Amide Inducer Enabling Chemical Diversity
Published in Journal of the American Chemical Society (13-06-2012)“…Access to homogeneous and discrete folded peptoid structures primarily depends on control of the cis/trans isomerism of backbone tertiary amides. This can be…”
Get full text
Journal Article -
2
Length-Selective Synthesis of Acylglycerol-Phosphates through Energy-Dissipative Cycling
Published in Journal of the American Chemical Society (06-03-2019)“…The main aim of origins of life research is to find a plausible sequence of transitions from prebiotic chemistry to nascent biology. In this context,…”
Get full text
Journal Article -
3
1,2,3-Triazolium-Based Peptoid Oligomers
Published in Journal of organic chemistry (03-03-2017)“…The cis-directing effect of the 1,2,3-triazolium-type side chain was studied on dimeric peptoid models with various patterns: αα, αβ, βα and ββ. Low influences…”
Get full text
Journal Article -
4
In vivo spatiotemporal control of voltage-gated ion channels by using photoactivatable peptidic toxins
Published in Nature communications (20-01-2022)“…Photoactivatable drugs targeting ligand-gated ion channels open up new opportunities for light-guided therapeutic interventions. Photoactivable toxins…”
Get full text
Journal Article -
5
Cyclic α,β-Tetrapeptoids: Sequence-Dependent Cyclization and Conformational Preference
Published in Organic letters (19-07-2013)“…The presence of at least one N-Cα branched side chain is crucial for successful cyclization of α,β-tetrapeptoids. The ctct amide sequence revealed in the…”
Get full text
Journal Article -
6
Convenient Solution-Phase Synthesis and Conformational Studies of Novel Linear and Cyclic α,β-Alternating Peptoids
Published in Organic letters (17-09-2009)“…The synthesis of a novel family of peptidomimetics composed of linear and cyclic α,β-alternating peptoids is described. Oligomers consisting of up to six…”
Get full text
Journal Article -
7
3-Substituted prolines: from synthesis to structural applications, from peptides to foldamers
Published in Molecules (Basel, Switzerland) (19-02-2013)“…Among the twenty natural proteinogenic amino acids, proline is unique as its secondary amine forms a tertiary amide when incorporated into biopolymers, thus…”
Get full text
Journal Article Book Review -
8
Fluorescent analogues of BeKm-1 with high and specific activity against the hERG channel
Published in Toxicon X (01-04-2019)“…Peptidic toxins that target specifically mammalian channels and receptors can be found in the venom of animals. These toxins are rarely used directly as tools…”
Get full text
Journal Article -
9
Synthetic Analogues of Huwentoxin-IV Spider Peptide With Altered Human NaV1.7/NaV1.6 Selectivity Ratios
Published in Frontiers in cell and developmental biology (20-12-2021)“…Huwentoxin-IV (HwTx-IV), a peptide discovered in the venom of the Chinese bird spider Cyriopagopus schmidti , has been reported to be a potent antinociceptive…”
Get full text
Journal Article -
10
Effect of capping groups at the N- and C-termini on the conformational preference of α,β-peptoids
Published in Organic & biomolecular chemistry (07-02-2012)Get more information
Journal Article -
11
Structure-function relationship of new peptides activating human Nav1.1
Published in Biomedicine & pharmacotherapy (01-09-2023)“…Nav1.1 is an important pharmacological target as this voltage-gated sodium channel is involved in neurological and cardiac syndromes. Channel activators are…”
Get full text
Journal Article -
12
Structure-function relationship of new peptides activating human Na v 1.1
Published in Biomedicine & pharmacotherapy (13-07-2023)“…Na 1.1 is an important pharmacological target as this voltage-gated sodium channel is involved in neurological and cardiac syndromes. Channel activators are…”
Get full text
Journal Article -
13
Synthetic Analogues of Huwentoxin-IV Spider Peptide With Altered Human Na V 1.7/Na V 1.6 Selectivity Ratios
Published in Frontiers in cell and developmental biology (2021)“…Huwentoxin-IV (HwTx-IV), a peptide discovered in the venom of the Chinese bird spider , has been reported to be a potent antinociceptive compound due to its…”
Get full text
Journal Article -
14
Convenient Solution-Phase Synthesis and Conformational Studies of Novel Linear and Cyclic ,-Alternating Peptoids
Published in Organic letters (2009)“…The synthesis of a novel family of peptidomimetics composed of linear and cyclic α,β-alternating peptoids is described. Oligomers consisting of up to six…”
Get full text
Journal Article