Search Results - "Caudron, Maïwen"

Alu element-containing RNAs maintain nucleolar structure and function by Caudron-Herger, Maïwen, Pankert, Teresa, Seiler, Jeanette, Németh, Attila, Voit, Renate, Grummt, Ingrid, Rippe, Karsten

“…Non‐coding RNAs play a key role in organizing the nucleus into functional subcompartments. By combining fluorescence microscopy and RNA deep‐sequencing‐based…”
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Spatial Coordination of Spindle Assembly by Chromosome-Mediated Signaling Gradients by Caudron, Mai̊wen, Bunt, Gertrude, Bastiaens, Philippe, Karsenti, Eric

“…During cell division, chromosomes are distributed to daughter cells by the mitotic spindle. This system requires spatial cues to reproducibly self-organize. We…”
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Loss of the abundant nuclear non-coding RNA MALAT1 is compatible with life and development by Eißmann, Moritz, Gutschner, Tony, Hämmerle, Monika, Günther, Stefan, Caudron-Herger, Maïwen, Groß, Matthias, Schirmacher, Peter, Rippe, Karsten, Braun, Thomas, Zörnig, Martin, Diederichs, Sven

“…The metastasis-associated lung adenocarcinoma transcript 1, MALAT1, is a long non-coding RNA (lncRNA) that has been discovered as a marker for lung cancer…”
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Genome organization: Balancing stability and plasticity by Wachsmuth, Malte, Caudron-Herger, Maïwen, Rippe, Karsten

“…The cell needs to stably maintain its genome and protect it from uncontrolled modifications that would compromise its function. At the same time, the genome…”
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Isolation of the protein and RNA content of active sites of transcription from mammalian cells by Melnik, Svitlana, Caudron-Herger, Maïwen, Brant, Lilija, Carr, Ian M, Rippe, Karsten, Cook, Peter R, Papantonis, Argyris

“…Transcription factories contain all three mammalian RNA polymerases, each actively transcribing a different subset of genes. This protocol describes how to…”
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Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate by Yokoyama, Hideki, Gruss, Oliver J, Rybina, Sofia, Caudron, Maïwen, Schelder, Malgorzata, Wilm, Matthias, Mattaj, Iain W, Karsenti, Eric

“…Production of Ran-guanosine triphosphate (GTP) around chromosomes induces local nucleation and plus end stabilization of microtubules (MTs). The nuclear…”
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Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB by Garding, Angela, Bhattacharya, Nupur, Claus, Rainer, Ruppel, Melanie, Tschuch, Cordula, Filarsky, Katharina, Idler, Irina, Zucknick, Manuela, Caudron-Herger, Maïwen, Oakes, Christopher, Fleig, Verena, Keklikoglou, Ioanna, Allegra, Danilo, Serra, Leticia, Thakurela, Sudhir, Tiwari, Vijay, Weichenhan, Dieter, Benner, Axel, Radlwimmer, Bernhard, Zentgraf, Hanswalter, Wiemann, Stefan, Rippe, Karsten, Plass, Christoph, Döhner, Hartmut, Lichter, Peter, Stilgenbauer, Stephan, Mertens, Daniel

“…Non-coding RNAs are much more common than previously thought. However, for the vast majority of non-coding RNAs, the cellular function remains enigmatic. The…”
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XMAP215-EB1 interaction is required for proper spindle assembly and chromosome segregation in Xenopus egg extract by Kronja, Iva, Kruljac-Letunic, Anamarija, Caudron-Herger, Maïwen, Bieling, Peter, Karsenti, Eric

“…In metaphase Xenopus egg extracts, global microtubule growth is mainly promoted by two unrelated microtubule stabilizers, end-binding protein 1 (EB1) and…”
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Refining the pool of RNA-binding domains advances the classification and prediction of RNA-binding proteins by Wassmer, Elsa, Koppány, Gergely, Hermes, Malte, Diederichs, Sven, Caudron-Herger, Maïwen

“…Abstract From transcription to decay, RNA-binding proteins (RBPs) influence RNA metabolism. Using the RBP2GO database that combines proteome-wide RBP screens…”
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The lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance by Seiler, Jana, Breinig, Marco, Caudron-Herger, Maïwen, Polycarpou-Schwarz, Maria, Boutros, Michael, Diederichs, Sven

“…Little is known about the function of most non-coding RNAs (ncRNAs). The majority of long ncRNAs (lncRNAs) is expressed at very low levels and it is a matter…”
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Coding RNAs with a non-coding function: Maintenance of open chromatin structure by Caudron-Herger, Maïwen, Müller-Ott, Katharina, Mallm, Jan-Philipp, Marth, Caroline, Schmidt, Ute, Fejes-Tóth, Katalin, Rippe, Karsten

“…The multi-layered organization of the genome in a large nucleoprotein complex termed chromatin regulates nuclear functions by establishing subcompartments with…”
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The challenges of investigating RNA function by Yang, Li, Ulitsky, Igor, Gilbert, Wendy V, Yi, Chengqi, Ule, Jernej, Caudron-Herger, Maïwen

“…High-throughput sequencing methods have led to the discovery of many non-coding RNAs, RNA modifications, and protein-RNA interactions. While the list keeps…”
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A pan-cancer analysis of synonymous mutations by Sharma, Yogita, Miladi, Milad, Dukare, Sandeep, Boulay, Karine, Caudron-Herger, Maiwen, Groß, Matthias, Backofen, Rolf, Diederichs, Sven

“…Synonymous mutations have been viewed as silent mutations, since they only affect the DNA and mRNA, but not the amino acid sequence of the resulting protein…”
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Nuclear architecture by RNA by Caudron-Herger, Maïwen, Rippe, Karsten

“…The dynamic organization of the cell nucleus into subcompartments with distinct biological activities represents an important determinant of cell function…”
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Genome-wide nucleosome positioning during embryonic stem cell development by Teif, Vladimir B, Vainshtein, Yevhen, Caudron-Herger, Maïwen, Mallm, Jan-Philipp, Marth, Caroline, Höfer, Thomas, Rippe, Karsten

“…Tissue- and disease-specific features of nucleosome positioning have recently been reported. A new study set out to identify features of nucleosome positioning…”
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Dissecting the nascent human transcriptome by analysing the RNA content of transcription factories by Caudron-Herger, Maïwen, Cook, Peter R, Rippe, Karsten, Papantonis, Argyris

“…While mapping total and poly-adenylated human transcriptomes has now become routine, characterizing nascent transcripts remains challenging, largely because…”
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Regulation of nucleolus assembly by non-coding RNA polymerase II transcripts by Caudron-Herger, Maïwen, Pankert, Teresa, Rippe, Karsten

“…The nucleolus is a nuclear subcompartment for tightly regulated rRNA production and ribosome subunit biogenesis. It also acts as a cellular stress sensor and…”
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Conformation of Reconstituted Mononucleosomes and Effect of Linker Histone H1 Binding Studied by Scanning Force Microscopy by Kepert, Jochen Felix, Tóth, Katalin Fejes, Caudron, Maïwen, Mücke, Norbert, Langowski, Jörg, Rippe, Karsten

“…The conformation of mononucleosome complexes reconstituted with recombinant core histones on a 614-basepair-long DNA fragment containing the Xenopus borealis…”
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Insights from the degradation mechanism of cyclin D into targeted therapy of the cancer cell cycle by Caudron-Herger, Maiwen, Diederichs, Sven

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Multiscale Analysis of Dynamics and Interactions of Heterochromatin Protein 1 by Fluorescence Fluctuation Microscopy by Müller, Katharina P., Erdel, Fabian, Caudron-Herger, Maïwen, Marth, Caroline, Fodor, Barna D., Richter, Mario, Scaranaro, Manuela, Beaudouin, Joël, Wachsmuth, Malte, Rippe, Karsten

“…Heterochromatin protein 1 (HP1) is a central factor in establishing and maintaining the repressive heterochromatin state. To elucidate its mobility and…”
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