Search Results - "Caudill, M.A"
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MTHFR deficiency or reduced intake of folate or choline in pregnant mice results in impaired short-term memory and increased apoptosis in the hippocampus of wild-type offspring
Published in Neuroscience (06-08-2015)“…Highlights • Maternal MTHFR deficiency in mice resulted in short-term memory impairment in pups. • Reduced maternal dietary folate or choline also led to…”
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Effects of dietary rumen-protected choline supplementation on colostrum yields, quality, and choline metabolites from dairy cattle
Published in JDS communications (01-07-2022)“…Colostrum is a critical nutrient source that provides passive immunity to dairy calves. Choline is a trimethylated molecule that is frequently supplemented in…”
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Dietary and genetic manipulations of folate metabolism differentially affect neocortical functions in mice
Published in Neurotoxicology and teratology (01-07-2013)“…Abstract Converging evidence suggests that folate-mediated one-carbon metabolism may modulate cognitive functioning throughout the lifespan, but few studies…”
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A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development
Published in Human molecular genetics (15-09-2013)“…Genetic variants in one-carbon folate metabolism have been identified as risk factors for disease because they may impair the production or use of one-carbon…”
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Choline intake, plasma riboflavin, and the phosphatidylethanolamine N-methyltransferase G5465A genotype predict plasma homocysteine in folate-deplete Mexican-American men with the methylenetetrahydrofolate reductase 677TT genotype
Published in The Journal of nutrition (01-04-2009)“…We previously showed that provision of the folate recommended dietary allowance and either 300, 550, 1100, or 2200 mg/d choline for 12 wk resulted in…”
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The methylenetetrahydrofolate reductase 677TT genotype and folate intake interact to lower global leukocyte DNA methylation in young Mexican American women
Published in Nutrition research (New York, N.Y.) (2007)“…Abstract DNA methylation is an epigenetic feature associated with X chromosome inactivation, genomic imprinting, transcriptional silencing of genes, and…”
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Personalized Nutrition: Nutritional Genomics as a Potential Tool for Targeted Medical Nutrition Therapy
Published in Nutrition reviews (01-07-2007)“…An emerging goal of medical nutrition therapy is to tailor dietary advice to an individual's genetic profile. In the United States and elsewhere,…”
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Ethnicity and race influence the folate status response to controlled folate intakes in young women
Published in The Journal of nutrition (01-07-2004)“…Population-based studies report differences in folate status indicators among Mexican American (MA), African American (AA) and Caucasian (CA) women. It is…”
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Additional food folate derived exclusively from natural sources improves folate status in young women with the MTHFR 677 CC or TT genotype
Published in The Journal of nutritional biochemistry (01-11-2006)“…The effectiveness of additional food folate in improving folate status in humans is uncertain particularly in people with the common genetic variant (677 C→T)…”
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Folate catabolism in pregnant and nonpregnant women with controlled folate intakes
Published in The Journal of nutrition (01-02-1998)“…Measurement of the urinary folate catabolites, para-aminobenzoylglutamate (pABG) and the more predominant acetylated form, acetamidobenzoylglutamate (apABG),…”
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