Search Results - "Cattrini, Carlo"
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Genetic aberrations in DNA repair pathways: a cornerstone of precision oncology in prostate cancer
Published in British journal of cancer (02-02-2021)“…Over the past years, several studies have demonstrated that defects in DNA damage response and repair (DDR) genes are present in a significant proportion of…”
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CDK4/6 inhibitors in advanced hormone receptor-positive/HER2-negative breast cancer: a systematic review and meta-analysis of randomized trials
Published in Breast cancer research and treatment (01-11-2018)“…Purpose Combining CDK4/6 inhibitors and endocrine therapy (ET) improved outcomes for the treatment of metastatic HR+/HER2− breast cancers. Here, we performed a…”
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BRCA Mutations in Prostate Cancer: Prognostic and Predictive Implications
Published in Journal of oncology (2020)“…Despite chemotherapy and novel androgen-receptor signalling inhibitors (ARSi) have been approved during the last decades, metastatic castration-resistant…”
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Untargeted lipidomics reveal association of elevated plasma C18 ceramide levels with reduced survival in metastatic castration-resistant prostate cancer patients
Published in Scientific reports (18-10-2023)“…Emerging evidence highlights the potential prognostic relevance of circulating lipids in metastatic castration-resistant prostate cancer (mCRPC), with a…”
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Is there a preferred first-line therapy for metastatic renal cell carcinoma? A network meta-analysis
Published in Therapeutic advances in urology (2021)“…Background: In recent years, new therapeutic combinations based on immunotherapy provided significant benefits as a first-line treatment for patients with…”
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A hnRNP K⁻AR-Related Signature Reflects Progression toward Castration-Resistant Prostate Cancer
Published in International journal of molecular sciences (30-06-2018)“…The major challenge in castration-resistant prostate cancer (CRPC) remains the ability to predict the clinical responses to improve patient selection for…”
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Medical Liability in Cancer Care During COVID-19 Pandemic: Heroes or Guilty?
Published in Frontiers in public health (18-12-2020)“…The COVID-19 outbreak rapidly became a public health emergency affecting particularly the frail category as cancer patients. This led oncologists to radical…”
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To switch or not to switch? A real-life experience using dexamethasone in combination with abiraterone
Published in Therapeutic advances in urology (2019)“…The recently published phase II prospective SWITCH trial evaluated whether patients with metastatic castration-resistant prostate cancer (mCRPC) treated with…”
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The role of mean corpuscular volume and red cell distribution width in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors: the MARECAP retrospective study
Published in Therapeutic advances in urology (01-01-2023)“…Background: Tyrosine-kinase inhibitors (TKIs) and immunotherapy represent the backbone treatment for metastatic renal cell carcinoma (mRCC) patients. The aim…”
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Integrative Analysis of Periostin in Primary and Advanced Prostate Cancer
Published in Translational oncology (01-07-2020)“…Periostin (POSTN) is an extracellular matrix protein associated with tumor progression and shorter survival in prostate cancer (PCa). Here, we performed an…”
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Association Between Second Progression-free Survival (PFS2) and Overall Survival in Metastatic Castration-resistant Prostate Cancer
Published in European urology (01-06-2020)Get full text
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Insulin/IGF Axis in Breast Cancer: Clinical Evidence and Translational Insights
Published in Biomolecules (Basel, Switzerland) (19-01-2021)“…Breast cancer (BC) is the most common neoplasm in women. Many clinical and preclinical studies investigated the possible relationship between host metabolism…”
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Serum Biomarkers to Dynamically Predict the Risk of Cardiovascular Events in Patients under Oncologic Therapy. A Multicenter Observational Study
Published in Reviews in cardiovascular medicine (01-07-2024)“…Serum biomarkers have been investigated as predictive risk factors for cancer-related cardiovascular (CV) risk, but their analysis is limited to their baseline…”
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Integrating Red Blood Cell Features and Hemoglobin Levels in Metastatic Renal Cell Carcinoma Patients Treated with Pazopanib or Cabozantinib: An Easily Exploitable Prognostic Score
Published in Frontiers in bioscience (Elite edition) (28-07-2023)“…BACKGROUNDThe advent of immune checkpoint inhibitors (ICIs) has revolutionized the metastatic renal cell carcinoma (mRCC) therapeutic landscape. Nevertheless,…”
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Etoposide and topoisomerase II inhibition for aggressive prostate cancer: Data from a translational study
Published in Cancer treatment and research communications (2020)“…•Etoposide is a chemotherapeutic agent that shows significant activity in preclinical models of prostate cancer and increased activity is observed in the most…”
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Abiraterone acetate and prednisone in the pre- and post-docetaxel setting for metastatic castration-resistant prostate cancer: a mono-institutional experience focused on cardiovascular events and their impact on clinical outcomes
Published in Therapeutic advances in medical oncology (01-01-2018)“…Background: The aim of this work was to to evaluate the incidence and risk factors of adverse events (AEs), focusing on cardiovascular events (CVEs) and…”
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Assessing the effectiveness and safety of lenvatinib and everolimus in advanced renal cell carcinoma: insights from the RELIEVE study's analysis of heavily pretreated patients
Published in Therapeutic advances in urology (01-01-2024)“…The treatment of heavily pretreated patients with metastatic renal cell carcinoma (mRCC) represents an unmet medical need and is still challenging. The primary…”
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GU-CA-COVID: a clinical audit among Italian genitourinary oncologists during the first COVID-19 outbreak
Published in Therapeutic advances in urology (2021)“…Background: Considering the growing genitourinary (GU) cancer population undergoing systemic treatment with immune checkpoint inhibitors (ICIs) in the context…”
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Atezolizumab and bladder cancer: facing a complex disease
Published in The Lancet (British edition) (27-01-2018)“…In 2016, Rosenberg and colleagues published the results of this programmed death ligand 1 (PD-L1) inhibitor in patients who had previously received…”
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