Search Results - "Catto, Andrew J."

Predictive variables for mortality after acute ischemic stroke by CARTER, Angela M, CATTO, Andrew J, MANSFIELD, Michael W, BAMFORD, John M, GRANT, Peter J

“…Stroke is a major healthcare issue worldwide with an incidence comparable to coronary events, highlighting the importance of understanding risk factors for…”
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Proteolytic mechanisms in amyloid-β metabolism: therapeutic implications for Alzheimer's disease by Vardy, Emma R.L.C., Catto, Andrew J., Hooper, Nigel M.

“…The accumulation of the amyloid-β peptide, the main constituent of the ‘amyloid plaque’, is widely considered to be the key pathological event in Alzheimer's…”
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Clustering of thrombotic factors with insulin resistance in South Asian patients with ischaemic stroke by Kain, Kirti, Catto, Andrew J, Grant, Peter J

“…We aimed to investigate significant correlations of insulin resistance with thrombotic factors in South Asians with stroke. Correlations of Homeostasis Model…”
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Elevated C-Reactive Protein and Long-Term Mortality After Ischaemic Stroke : Relationship With Markers of Endothelial Cell and Platelet Activation by SHANTIKUMAR, Saran, GRANT, Peter J, CATTO, Andrew J, BAMFORD, John M, CARTER, Angela M

“…Inflammatory biomarkers predict development of atherothrombotic events. In the present study we examined the relationships between C-reactive protein (CRP),…”
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Coagulation factor VII activity, Arg/Gln353 polymorphism and features of insulin resistance in first-degree-relatives of South Asian patients with stroke by Kain, Kirti, Catto, Andrew J, Young, John, Bamford, John, Bavington, John, Grant, Peter J

“…The aim of the study was to determine associations of factor VII:C levels in 140 South Asian stroke subjects and 143 first-degree relatives versus age-sex…”
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Complement C3 and C-reactive protein are elevated in South Asians independent of a family history of stroke by SOMANI, Riyaz, GRANT, Peter J, KAIN, Kirti, CATTO, Andrew J, CARTER, Angela M

“…Complement components are emerging risk factors for cardiovascular disease. In this study, we examined the relation among C3, C-reactive protein (CRP), factor…”
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Plasma angiotensin-converting enzyme in Alzheimer's disease by Vardy, Emma R L C, Rice, Penny J, Bowie, Peter C W, Holmes, John D, Catto, Andrew J, Hooper, Nigel M

“…The insertion allele in the gene encoding angiotensin-converting enzyme (ACE) is a risk factor for Alzheimer's disease (AD) and ACE is one of several…”
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Factor XIII Val 34 Leu : A novel association with primary intracerebral hemorrhage by CATTO, A. J, KOHLER, H. P, BANNAN, S, STICKLAND, M, CARTER, A, GRANT, P. J

“…A common G-to-T point mutation (Val 34 Leu) in exon 2 of the alpha-subunit of the factor XIII is strongly negatively associated with the development of…”
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Association of the α-fibrinogen Thr312Ala polymorphism with poststroke mortality in subjects with atrial fibrillation by CARTER, A. M, CATTO, A. J, GRANT, P. J

“…The alpha-fibrinogen Thr312Ala polymorphism occurs in close proximity to several sites important for factor XIIIa-dependent cross-linking, which raises the…”
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Impaired fibrinolysis and increased fibrinogen levels in South Asian subjects by Kain, Kirti, Catto, Andrew J., Grant, Peter J.

“…The potential role of haemostatic risk markers is largely unexplored in South Asians, who have increased morbidity and mortality from cardiovascular disease…”
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Coagulation factor XIII B subunit antigen, FXIIIVal34Leu genotype and ischaemic stroke in South Asians by Kain, Kirti, Young, John, Bavington, John, Bamford, John, Catto, Andrew J

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von Willebrand factor and factor VIII: C in acute cerebrovascular disease. Relationship to stroke subtype and mortality by Catto, A J, Carter, A M, Barrett, J H, Bamford, J, Rice, P J, Grant, P J

“…Elevated von Willebrand factor (vWF) is a risk factor in the development of acute myocardial infarction. The importance of vWF and factor VII:C in the…”
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Plasminogen activator inhibitor-1 (PAI-1) 4G/5G promoter polymorphism and levels in subjects with cerebrovascular disease by Catto, A J, Carter, A M, Stickland, M, Bamford, J M, Davies, J A, Grant, P J

“…The exact role of the fibrinolytic system in the pathogenesis of stroke remains to be established. Elevated circulating levels of plasminogen activator…”
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Association of the platelet glycoprotein IIb HPA-3 polymorphism with survival after acute ischemic stroke by CARTER, A. M, CATTO, A. J, BAMFORD, J. M, GRANT, P. J

“…The role of polymorphisms of the platelet glycoprotein (GP) IIb/IIIa receptor in the development of cardiovascular disease has been the subject of intensive…”
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Increased fibrinogen, von Willebrand factor and tissue plasminogen activator levels in insulin resistant South Asian patients with ischaemic stroke by Kain, Kirti, Catto, Andrew J., Young, John, Bamford, John, Bavington, John, Grant, Peter J.

“…The aim of this study was to determine differences in atherothrombotic risk factors in South Asian subjects with a history of ischaemic stroke and South Asian…”
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Increased Fibrinogen Levels among South Asians versus Whites in the United Kingdom Are Not Explained by Common Polymorphisms by Kain, Kirti, Blaxill, Jonathan M., Catto, Andrew J., Grant, Peter J., Carter, Angela M.

“…Determinants of fibrinogen level among South Asians are not established. In 1997–1999, plasma fibrinogen levels and prevalences of the fibrinogen polymorphisms…”
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Decreased fibrinolytic potential in South Asian women with ischaemic cerebrovascular disease by Kain, Kirti, Catto, Andrew J., Carter, Angela M., Young, John, Bamford, John, Bavington, John, Grant, Peter J.

“…To investigate gender differences in conventional, coagulation and fibrinolytic factors in South Asian ischaemic stroke patients, we compared these variables…”
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Factor XIII A‐subunit concentration predicts outcome in stroke subjects and vascular outcome in healthy, middle‐aged men by Kohler, Hans P., Ariëns, Robert A. S., Catto, Andrew J., Carter, Angela M., Miller, George J., Cooper, Jackie A., Mansfield, Michael W., Standeven, Kristina F., Grant, Peter J.

“…There is growing evidence for a role of factor XIII (FXIII) in vascular disease. FXIII measures were determined in (i) a nested case–control study from the…”
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Insulin resistance and elevated levels of tissue plasminogen activator in first-degree relatives of South Asian patients with ischemic cerebrovascular disease by KAIN, Kirti, CATTO, Andrew J, YOUNG, John, BAMFORD, John, BAVINGTON, John, GRANT, Peter J

“…South Asians in the United Kingdom suffer from an increased mortality from cerebrovascular disease compared with whites. Evidence suggests that the relatives…”
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Polymorphisms of the factor VII gene and circulating FVII:C levels in relation to acute cerebrovascular disease and poststroke mortality by HEYWOOD, D. M, CARTER, A. M, CATTO, A. J, BAMFORD, J. M, GRANT, P. J

“…FVII:C has been shown to be an independent risk factor for myocardial infarction and is related to environmental and genetic factors. This study sought to…”
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