Search Results - "Cattley, Richard"

T cells transduce T-cell receptor signal strength by generating different phosphatidylinositols by Hawse, William F., Cattley, Richard T.

“…T-cell receptor (TCR) signaling strength is a dominant factor regulating T-cell differentiation, thymic development, and cytokine signaling. The molecular…”
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The AKT kinase signaling network is rewired by PTEN to control proximal BCR signaling in germinal center B cells by Luo, Wei, Hawse, William, Conter, Laura, Trivedi, Nikita, Weisel, Florian, Wikenheiser, Daniel, Cattley, Richard T., Shlomchik, Mark J.

“…B cell antigen receptor (BCR) and CD40 signaling are rewired in germinal center (GC) B cells (GCBCs) to optimize selection for high-affinity B cells. In GCBC,…”
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Transforming growth factor β (TGF-β) receptor signaling regulates kinase networks and phosphatidylinositol metabolism during T-cell activation by Cattley, Richard T., Lee, Mijoon, Boggess, William C., Hawse, William F.

“…The cytokine content in tissue microenvironments shapes the functional capacity of a T cell. This capacity depends on the integration of extracellular…”
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Cutting Edge: TCR Signal Strength Regulates Acetyl-CoA Metabolism via AKT by Hawse, William F, Cattley, Richard T, Wendell, Stacy G

“…TCR signaling activates kinases including AKT/mTOR that engage metabolic networks to support the energetic demands of a T cell during an immune response. It is…”
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Synergistic and additive interactions between receptor signaling networks drive the regulatory T cell versus T helper 17 cell fate choice by Prado, Douglas S., Cattley, Richard T., Shipman, Corey W., Happe, Cassandra, Lee, Mijoon, Boggess, William C., MacDonald, Matthew L., Hawse, William F.

“…CD4+ T cells differentiate into subsets that promote immunity or minimize damage to the host. T helper 17 cells (Th17) are effector cells that function in…”
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Quantification of larval zebrafish motor function in multiwell plates using open-source MATLAB applications by Zhou, Yangzhong, Cattley, Richard T, Cario, Clinton L, Bai, Qing, Burton, Edward A

“…In this article, the authors provide directions on using the open-source MATLAB applications LSRtrack and LSRanalyze to quantitatively follow the movements of…”
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Histone acetyltransferase CBP is critical for conventional effector and memory T-cell differentiation in mice by Piccirillo, Ann R., Cattley, Richard T., D'Cruz, Louise M., Hawse, William F.

“…Compared with naïve T cells, memory CD8+ T cells have a transcriptional landscape and proteome that are optimized to generate a more rapid and robust response…”
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Antiviral epithelial-macrophage crosstalk permits secondary bacterial infections by Lane, Sidney, White, Tristan L A, Walsh, Erin E, Cattley, Richard T, Cumberland, Rachel, Hawse, William F, Delgoffe, Greg M, Badylak, Stephen F, Bomberger, Jennifer M

“…Miscommunication of antiviral and antibacterial immune signals drives worsened morbidity and mortality during respiratory viral-bacterial coinfections…”
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The Capture of a Disabled Proteasome Identifies Erg25 as a Substrate for Endoplasmic Reticulum Associated Degradation by Buck, Teresa M., Zeng, Xuemei, Cantrell, Pamela S., Cattley, Richard T., Hasanbasri, Zikri, Yates, Megan E., Nguyen, Diep, Yates, Nathan A., Brodsky, Jeffrey L.

“…We report on an engineered yeast strain that allows for the facile isolation of the proteasome and associated proteasome substrates after rapid inactivation…”
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Rubicon promotes rather than restricts murine lupus and is not required for LC3-associated phagocytosis by Gordon, Rachael A, Giannouli, Christina, Raparia, Chirag, Bastacky, Sheldon I, Marinov, Anthony, Hawse, William, Cattley, Richard, Tilstra, Jeremy S, Campbell, Allison M, Nickerson, Kevin M, Davidson, Anne, Shlomchik, Mark J

“…NADPH oxidase deficiency exacerbates lupus in murine models and patients, but the mechanisms remain unknown. It is hypothesized that NADPH oxidase suppresses…”
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Multiple protein kinase pathways mediate amplified IL-6 release by human lung fibroblasts co-exposed to nickel and TLR-2 agonist, MALP-2 by Gao, Fei, Brant, Kelly A., Ward, Rachel M., Cattley, Richard T., Barchowsky, Aaron, Fabisiak, James P.

“…Microbial stimuli and atmospheric particulate matter (PM) interact to amplify the release of inflammatory and immune-modulating cytokines. The basis of this…”
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The calpain/ABCA1 pathway drives mast cell- initiated vascular leakage and inflammation in the skin by Kohl, Lisa Marie, Hay, Ahnika, Gupta, Vinay, Williams, Li'an, Bharadwaj, Shreya, Donahue, McKenna, Omar, Lea, Cattley, Richard, Sumpter, Tina

“…Abstract Cutaneous mast cells (MCs) initiate local and systemic immune responses. To reach this end, activated MCs immediately release an arsenal of…”
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The long noncoding RNA LUCAT1 promotes immune gene expression in human macrophages by Vergara, Kevin E, Lal, Sneha, Cattley, Richard, Hawse, William F, Atianand, Maninjay

“…Abstract Long noncoding RNAs (lncRNA) are transcripts larger than 200 nucleotides that mediate their molecular function in an RNA-dependent manner by…”
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Neurokinin A blocks the ABCA1 channel to promote IL-10-dependent mast cell regulation by Williams, Li’an, Hawse, William F, Cattley, Richard, Carey, Cara D, Zhang, Jiying, Falo, Louis D, Larregina, Adriana T, Sumpter, Tina L

“…Abstract Cutaneous mast cells (MCs) reside in close proximity to peripheral sensory nerve fibers and are susceptible to regulation by neuropeptides. The…”
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Deletion of AMPK Reduces Oxidative Metabolism in Gvhd-Causing Human T Cells by Ramgopal, Archana, Braverman, Erica, Sun, Lee-Kai, Monlish, Darlene, Wittmann, Christopher, Ramsey, Manda Jo, Cattley, Richard, Hawse, William, Byersdorfer, Craig Alan

“…Following allogeneic transplantation, alloreactive T cells exhibit heightened metabolic requirements that represent a promising area for therapeutic…”
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AMPK drives both glycolytic and oxidative metabolism in murine and human T cells during graft-versus-host disease by Ramgopal, Archana, Braverman, Erica L., Sun, Lee-Kai, Monlish, Darlene, Wittmann, Christopher, Kemp, Felicia, Qin, Mengtao, Ramsey, Manda J., Cattley, Richard, Hawse, William, Byersdorfer, Craig A.

“…•AMPK plays a key role in driving both and oxidative and glycolytic metabolism in T cells during GVHD.•Absence of AMPK simultaneously impairs both glycolytic…”
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Quantification of larval zebrafish motor function in multi-well plates using open-source MATLAB® applications by Zhou, Yangzhong, Cattley, Richard T., Cario, Clinton L., Bai, Qing, Burton, Edward A.

“…This article describes a method to quantify the movements of larval zebrafish in multi-well plates, using the open-source MATLAB® applications LSRtrack and…”
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Worcester Cathedral Bells by CATTLEY, RICHARD

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The New Bells Of St. Paul's by ELLACOMBE, H, CATTLEY, RICHARD

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