Search Results - "Cattaneo, Monica"

Longevity-Associated Variant of BPIFB4 Confers Neuroprotection in the STHdh Cell Model of Huntington Disease by Cattaneo, Monica, Maciag, Anna, Milella, Maria Serena, Ciaglia, Elena, Bruno, Antonino, Puca, Annibale Alessandro

“…Huntington's disease (HD) is caused by the production of mutant Huntingtin (mHTT), characterized by long polyglutamine repeats with toxic effects. There are…”
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Impact of BMI on Survival Outcomes of Immunotherapy in Solid Tumors: A Systematic Review by Indini, Alice, Rijavec, Erika, Ghidini, Michele, Tomasello, Gianluca, Cattaneo, Monica, Barbin, Francesca, Bareggi, Claudia, Galassi, Barbara, Gambini, Donatella, Grossi, Francesco

“…Growing research has focused on obesity as a prognostic factor during therapy with immune-checkpoint inhibitors (ICIs). The role of body-mass index (BMI) in…”
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Oscillating glucose induces microRNA-185 and impairs an efficient antioxidant response in human endothelial cells by La Sala, Lucia, Cattaneo, Monica, De Nigris, Valeria, Pujadas, Gemma, Testa, Roberto, Bonfigli, Anna R, Genovese, Stefano, Ceriello, Antonio

“…Intracellular antioxidant response to high glucose is mediated by Cu/Mn-superoxide dismutases (SOD-1/SOD-2), catalase (CAT) and glutathione peroxidases (GPx),…”
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Immunotherapy for colorectal cancer: where are we heading? by Basile, Debora, Garattini, Silvio Ken, Bonotto, Marta, Ongaro, Elena, Casagrande, Mariaelena, Cattaneo, Monica, Fanotto, Valentina, De Carlo, Elisa, Loupakis, Fotios, Urbano, Federica, Negri, Francesca V, Pella, Nicoletta, Russano, Marco, Brunetti, Oronzo, Scartozzi, Mario, Santini, Daniele, Silvestris, Nicola, Casadei Gardini, Andrea, Puzzoni, Marco, Calvetti, Lorenzo, Cardarelli, Nadia, Aprile, Giuseppe

“…In the last few years, significant advances in molecular biology have provided new therapeutic options for colorectal cancer (CRC). The development of new…”
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Effects of Human LAV-BPIFB4 Gene Therapy on the Epigenetic Clock and Health of Aged Mice by Giuliani, Maria Elisa, Barbi, Veronica, Bigossi, Giorgia, Marcozzi, Serena, Giacconi, Robertina, Cardelli, Maurizio, Piacenza, Francesco, Orlando, Fiorenza, Ciaglia, Elena, Cattaneo, Monica, Mongelli, Alessia, Gaetano, Carlo, Provinciali, Mauro, Puca, Annibale Alessandro, Malavolta, Marco

“…The homozygous genotype of the Longevity-Associated Variant (LAV) in Bactericidal/Permeability-Increasing Fold-Containing Family B member 4 (BPIFB4) is…”
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Healthy longevity-associated protein improves cardiac function in murine models of cardiomyopathy with preserved ejection fraction by Alvino, Valeria Vincenza, Slater, Sadie, Qiu, Yan, Cattaneo, Monica, Mohammed, Khaled Abdelsattar Kassem, Gate, Seamus, Sekar, Vealmurugan, Puca, Annibale Alessandro, Madeddu, Paolo

“…Abstract Aims Aging is influenced by genetic determinants and comorbidities, among which diabetes increases the risk for heart failure with preserved ejection…”
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Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38+ macrophages and NAD+ decline by Ciaglia, Elena, Lopardo, Valentina, Montella, Francesco, Carrizzo, Albino, Di Pietro, Paola, Malavolta, Marco, Giacconi, Robertina, Orlando, Fiorenza, Cattaneo, Monica, Madeddu, Paolo, Vecchione, Carmine, Puca, Annibale Alessandro

“…As we age, our body experiences chronic, systemic inflammation contributing to the morbidity and mortality of the elderly. The senescent immune system has been…”
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Solar drinking water disinfection (SODIS) to reduce childhood diarrhoea in rural Bolivia: a cluster-randomized, controlled trial by Mäusezahl, Daniel, Christen, Andri, Pacheco, Gonzalo Duran, Tellez, Fidel Alvarez, Iriarte, Mercedes, Zapata, Maria E, Cevallos, Myriam, Hattendorf, Jan, Cattaneo, Monica Daigl, Arnold, Benjamin, Smith, Thomas A, Colford, Jr, John M

“…Solar drinking water disinfection (SODIS) is a low-cost, point-of-use water purification method that has been disseminated globally. Laboratory studies suggest…”
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Longevity-associated BPIFB4 gene counteracts the inflammatory signaling by Cattaneo, Monica, Baragetti, Andrea, Malovini, Alberto, Ciaglia, Elena, Lopardo, Valentina, Olmastroni, Elena, Casula, Manuela, Ciacci, Carolina, Catapano, Alberico L, Puca, Annibale A

“…Increased levels of pro-inflammatory proteins in plasma can be detected in older individuals and associate with the so called chronic low-grade inflammation,…”
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Circulating BPIFB4 Levels Associate With and Influence the Abundance of Reparative Monocytes and Macrophages in Long Living Individuals by Ciaglia, Elena, Montella, Francesco, Lopardo, Valentina, Scala, Pasqualina, Ferrario, Anna, Cattaneo, Monica, Carrizzo, Albino, Malovini, Alberto, Madeddu, Paolo, Vecchione, Carmine, Puca, Annibale Alessandro

“…Long-Living Individuals (LLIs) delay aging and are less prone to chronic inflammatory reactions. Whether a distinct monocytes and macrophages repertoire is…”
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BPIFB4 and its longevity-associated haplotype protect from cardiac ischemia in humans and mice by Cattaneo, Monica, Aleksova, Aneta, Malovini, Alberto, Avolio, Elisa, Thomas, Anita, Alvino, Valeria Vincenza, Kilcooley, Michael, Pieronne-Deperrois, Marie, Ouvrard-Pascaud, Antoine, Maciag, Anna, Spinetti, Gaia, Kussauer, Sophie, Lemcke, Heiko, Skorska, Anna, Vasudevan, Praveen, Castiglione, Stefania, Raucci, Angela, David, Robert, Richard, Vincent, Beltrami, Antonio Paolo, Madeddu, Paolo, Puca, Annibale Alessandro

“…Long-living individuals (LLIs) escape age-related cardiovascular complications until the very last stage of life. Previous studies have shown that a…”
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A Model of Evolutionary Selection: The Cardiovascular Protective Function of the Longevity Associated Variant of BPIFB4 by Villa, Francesco, Carrizzo, Albino, Ferrario, Anna, Maciag, Anna, Cattaneo, Monica, Spinelli, Chiara Carmela, Montella, Francesco, Damato, Antonio, Ciaglia, Elena, Puca, Annibale Alessandro

“…Evolutionary forces select genetic variants that allow adaptation to environmental stresses. The genomes of centenarian populations could recapitulate the…”
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The Appropriateness of Invasive Ventilation in COVID-19 Positive Cancer Patients: Proposal of a New Prognostic Score by Ghidini, Michele, Indini, Alice, Rijavec, Erika, Bareggi, Claudia, Cattaneo, Monica, Tomasello, Gianluca, Galassi, Barbara, Gambini, Donatella, Grossi, Francesco

“…Over the last months, as oncology specialists, we have frequently been contacted for estimating prognosis for cancer patients affected by COVID-19 infection…”
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A donor splice site mutation in CISD2 generates multiple truncated, non-functional isoforms in Wolfram syndrome type 2 patients by Cattaneo, Monica, La Sala, Lucia, Rondinelli, Maurizio, Errichiello, Edoardo, Zuffardi, Orsetta, Puca, Annibale Alessandro, Genovese, Stefano, Ceriello, Antonio

“…Mutations in the gene that encodes CDGSH iron sulfur domain 2 (CISD2) are causative of Wolfram syndrome type 2 (WFS2), a rare autosomal recessive…”
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Delineating the cytogenomic and epigenomic landscapes of glioma stem cell lines by Baronchelli, Simona, Bentivegna, Angela, Redaelli, Serena, Riva, Gabriele, Butta, Valentina, Paoletta, Laura, Isimbaldi, Giuseppe, Miozzo, Monica, Tabano, Silvia, Daga, Antonio, Marubbi, Daniela, Cattaneo, Monica, Biunno, Ida, Dalprà, Leda

“…Glioblastoma multiforme (GBM), the most common and malignant type of glioma, is characterized by a poor prognosis and the lack of an effective treatment, which…”
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Additional congeners of the macrolide neaumycin: structure revision and biological activity by Simone, Matteo, Maffioli, Sonia I, Tocchetti, Arianna, Tretter, Stefano, Cattaneo, Monica, Biunno, Ida, Gaspari, Eleonora, Donadio, Stefano

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Down-modulation of SEL1L, an Unfolded Protein Response and Endoplasmic Reticulum-associated Degradation Protein, Sensitizes Glioma Stem Cells to the Cytotoxic Effect of Valproic Acid by Cattaneo, Monica, Baronchelli, Simona, Schiffer, Davide, Mellai, Marta, Caldera, Valentina, Saccani, Gloria Jotti, Dalpra, Leda, Daga, Antonio, Orlandi, Rosaria, DeBlasio, Pasquale, Biunno, Ida

“…Valproic acid (VPA), an histone deacetylase inhibitor, is emerging as a promising therapeutic agent for the treatments of gliomas by virtue of its ability to…”
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Renal Function Outcomes in Metastatic Non-Small-Cell Lung Carcinoma Patients Treated with Chemotherapy or Immune Checkpoint Inhibitors: An Unexpected Scenario by Trevisani, Francesco, Di Marco, Federico, Floris, Matteo, Pani, Antonello, Minnei, Roberto, Scartozzi, Mario, Cirillo, Alessio, Gelibter, Alain, Botticelli, Andrea, Rijavec, Erika, Cattaneo, Monica, Garrone, Ornella, Ghidini, Michele

“…Immune checkpoint inhibitors (ICIs) and platinum-based chemotherapy (CT) are effective therapeutic agents for the palliative treatment of metastatic…”
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Molecular classifications of gastric cancers: Novel insights and possible future applications by Garattini, Silvio Ken, Basile, Debora, Cattaneo, Monica, Fanotto, Valentina, Ongaro, Elena, Bonotto, Marta, Negri, Francesca V, Berenato, Rosa, Ermacora, Paola, Cardellino, Giovanni Gerardo, Giovannoni, Mariella, Pella, Nicoletta, Scartozzi, Mario, Antonuzzo, Lorenzo, Silvestris, Nicola, Fasola, Gianpiero, Aprile, Giuseppe

“…Despite some notable advances in the systemic management of gastric cancer(GC), the prognosis of patients with advanced disease remains overall poor and their…”
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Secretion of novel SEL1L endogenous variants is promoted by ER stress/UPR via endosomes and shed vesicles in human cancer cells by Cattaneo, Monica, Lotti, Lavinia Vittoria, Martino, Simone, Alessio, Massimo, Conti, Antonio, Bachi, Angela, Mariani-Costantini, Renato, Biunno, Ida

“…We describe here two novel endogenous variants of the human endoplasmic reticulum (ER) cargo receptor SEL1LA, designated p38 and p28. Biochemical and RNA…”
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