Search Results - "Cates, Justin M. M"
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Performance Analysis of the American Joint Committee on Cancer 8th Edition Staging System for Retroperitoneal Sarcoma and Development of a New Staging Algorithm for Sarcoma-Specific Survival
Published in Annals of surgical oncology (01-12-2017)“…Background The American Joint Committee on Cancer (AJCC) recently published the 8th edition of the AJCC Cancer Staging Manual . Major changes were made to the…”
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Risk Assessment of Visceral Sarcomas: A Comparative Study of 2698 Cases from the SEER Database
Published in Annals of surgical oncology (01-10-2021)“…Soft tissue sarcomas arising in visceral organs are rare and lack validated tumor-staging protocols. Clinicopathologic features and clinical outcomes of 2698…”
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Surgical resection margin classifications for high-grade pleomorphic soft tissue sarcomas of the extremity or trunk: definitions of adequate resection margins and recommendations for sampling margins from primary resection specimens
Published in Modern pathology (01-10-2019)“…Adequacy of surgical resection margins for soft tissue sarcomas are poorly defined because of the various classifications and definitions used in prior studies…”
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Targeted Next Generation Sequencing Identifies Markers of Response to PD-1 Blockade
Published in Cancer immunology research (01-11-2016)“…Therapeutic antibodies blocking programmed death-1 and its ligand (PD-1/PD-L1) induce durable responses in a substantial fraction of melanoma patients. We…”
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EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer
Published in Cancer research (Chicago, Ill.) (15-01-2016)“…Despite the success of treating EGFR-mutant lung cancer patients with EGFR tyrosine kinase inhibitors (TKI), all patients eventually acquire resistance to…”
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Staging soft tissue sarcoma of the head and neck: Evaluation of the AJCC 8th edition revised T classifications
Published in Head & neck (01-07-2019)“…Background The American Joint Committee on Cancer (AJCC) has proposed new T classifications for head and neck sarcomas in the 8th edition of the AJCC Cancer…”
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Diagnostic value of histone 3 mutations in osteoclast-rich bone tumors
Published in Human pathology (01-10-2017)“…Differentiating osteoclast-rich lesions of bone (giant cell tumor of bone [GCTB], chondroblastoma [CBA], and aneurysmal bone cyst [ABC]) can be challenging,…”
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Genetic and pharmacologic inhibition of EPHA2 promotes apoptosis in NSCLC
Published in The Journal of clinical investigation (01-05-2014)“…Genome-wide analyses determined previously that the receptor tyrosine kinase (RTK) EPHA2 is commonly overexpressed in non-small cell lung cancers (NSCLCs)…”
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Bisphosphonates Inhibit Osteosarcoma‐Mediated Osteolysis Via Attenuation of Tumor Expression of MCP‐1 and RANKL
Published in Journal of bone and mineral research (01-06-2014)“…ABSTRACT Osteosarcoma is the most common primary malignant tumor of bone and accounts for around 50% of all primary skeletal malignancies. In addition to novel…”
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Validation of a Radiography-Based Quantification Designed to Longitudinally Monitor Soft Tissue Calcification in Skeletal Muscle
Published in PloS one (20-07-2016)“…Soft tissue calcification, including both dystrophic calcification and heterotopic ossification, may occur following injury. These lesions have variable fates…”
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Fibrin Accumulation Secondary to Loss of Plasmin‐Mediated Fibrinolysis Drives Inflammatory Osteoporosis in Mice
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-08-2014)“…Objective Osteoporosis is a skeletal disorder characterized by low bone mass and increased bone fragility associated with aging, menopause, smoking, obesity,…”
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Plasmin Prevents Dystrophic Calcification After Muscle Injury
Published in Journal of bone and mineral research (01-02-2017)“…ABSTRACT Extensive or persistent calcium phosphate deposition within soft tissues after severe traumatic injury or major orthopedic surgery can result in pain…”
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Loss of FOXA1 Drives Sexually Dimorphic Changes in Urothelial Differentiation and Is an Independent Predictor of Poor Prognosis in Bladder Cancer
Published in The American journal of pathology (01-05-2015)“…We previously found loss of forkhead box A1 (FOXA1) expression to be associated with aggressive urothelial carcinoma of the bladder, as well as increased tumor…”
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Increasing tumor budding in cholangiocarcinoma is associated with decreased disease-specific survival
Published in Human pathology (01-05-2021)“…Tumor budding (TB) has been shown to be an adverse prognostic factor in several gastrointestinal malignancies, most notably colorectal carcinoma (CRC). TB has…”
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Hepatic micrometastases are associated with poor prognosis in patients with liver metastases from neuroendocrine tumors of the digestive tract
Published in Human pathology (01-09-2018)“…Pathologic examination of hepatic metastasectomies from patients with metastatic small intestinal or pancreatic neuroendocrine tumor frequently reveals…”
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Differential development of the distal and proximal femoral epiphysis and physis in mice
Published in Bone (New York, N.Y.) (01-01-2013)“…Abstract Many pathologic conditions of hip development result from aberrant vascularity with subsequent effects on physeal resorption and epiphyseal fusion. To…”
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The temporal and spatial development of vascularity in a healing displaced fracture
Published in Bone (New York, N.Y.) (01-10-2014)“…Abstract Underlying vascular disease is an important pathophysiologic factor shared among many co-morbid conditions associated with poor fracture healing, such…”
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Alveolar soft part sarcoma and granular cell tumor: an immunohistochemical comparison study
Published in Human pathology (01-05-2014)“…Summary Although the histologic features of alveolar soft part sarcoma and granular cell tumor are typically distinctive, occasional cases show a significant…”
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Loss of the urothelial differentiation marker FOXA1 is associated with high grade, late stage bladder cancer and increased tumor proliferation
Published in PloS one (10-05-2012)“…Approximately 50% of patients with muscle-invasive bladder cancer (MIBC) develop metastatic disease, which is almost invariably lethal. However, our…”
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Pleiotropic effects of bisphosphonates on osteosarcoma
Published in Bone (New York, N.Y.) (01-06-2014)“…Abstract Osteosarcoma is the most common primary malignant tumor of bone and accounts for half of all primary skeletal malignancies in children and teenagers…”
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