Search Results - "Cater, J."
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Substrate binding-induced conformational transitions in the omega-3 fatty acid transporter MFSD2A
Published in Nature communications (09-06-2023)“…Major Facilitator Superfamily Domain containing 2 A (MFSD2A) is a transporter that is highly enriched at the blood-brain and blood-retinal barriers, where it…”
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The Domain Interface of the Human Glutamate Transporter EAAT1 Mediates Chloride Permeation
Published in Biophysical journal (05-08-2014)“…The concentration of glutamate within the glutamatergic synapse is tightly regulated by the excitatory amino-acid transporters (EAATs). In addition to their…”
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The Split Personality of Glutamate Transporters: A Chloride Channel and a Transporter
Published in Neurochemical research (01-03-2016)“…Transporters and ion channels are conventionally categorised into distinct classes of membrane proteins. However, some membrane proteins have a split…”
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Outbreak of Anthrax in Livestock with Human Occupational Exposures - Minnesota, 2023
Published in Journal of agromedicine (01-07-2024)“…In July 2023, the Minnesota Department of Health (MDH) was notified of possible occupational exposures to anthrax during an outbreak in animals. In…”
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Modelling uptake and transport of therapeutic agents through the lymphatic system
Published in Computer methods in biomechanics and biomedical engineering (11-06-2022)“…The ability of the lymphatic network to absorb large molecules and bypass the first-pass liver metabolism makes it appealing as a delivery system for…”
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Food for thought: The molecular basis of nutrient uptake into the brain
Published in Science (American Association for the Advancement of Science) (27-09-2024)“…The molecular basis of nutrient uptake into the brain…”
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Quality of life in breast cancer survivors: An assessment of international breast cancer dragon boat racers
Published in Lymphology (2020)“…Resistance exercise is deemed safe for women recovering from conventional breast cancer therapies but few clinicians are aware that dragon boat racing, as a…”
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An Experimental and Numerical Investigation of CO2 Distribution in the Upper Airways During Nasal High Flow Therapy
Published in Annals of biomedical engineering (01-10-2016)“…Nasal high flow (NHF) therapy is used to treat a variety of respiratory disorders to improve patient oxygenation. A CO 2 washout mechanism is believed to be…”
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A boundary-integral representation for biphasic mixture theory, with application to the post-capillary glycocalyx
Published in Proceedings of the Royal Society. A, Mathematical, physical, and engineering sciences (08-07-2015)“…We describe a new boundary-integral representation for biphasic mixture theory, which allows us to efficiently solve certain elastohydrodynamic-mobility…”
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Carbon dioxide insufflation deflects airborne particles from an open surgical wound model
Published in The Journal of hospital infection (01-01-2017)“…Summary Background Surgical site infections remain a significant burden on healthcare systems and may benefit from new countermeasures. Aim To assess the…”
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The impact of twine/mesh ratio on the flow dynamics through a porous cylinder
Published in Experiments in fluids (01-10-2014)“…The impact of the twine/mesh ratio on the flow through a porous hollow cylinder of diameter D has been experimentally investigated at Reynolds number Re = 800…”
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Development of an in situ procedure to evaluate the reticulo-rumen morphology of sheep selected for divergent methane emissions
Published in Animal (Cambridge, England) (01-03-2019)“…Published studies have shown that methane yield (g CH4/kg dry matter) from sheep is positively correlated with the size (volume and surface area) of the…”
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Structural Insights into Transporter-Mediated Drug Resistance in Infectious Diseases
Published in Journal of molecular biology (06-08-2021)“…[Display omitted] •Transporter-mediated export is a major cause of resistance to anti-infectious agents.•Advances in structural biology have allowed for many…”
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A 10-year meta-analysis of membrane protein structural biology: Detergents, membrane mimetics, and structure determination techniques
Published in Biochimica et biophysica acta. Biomembranes (01-03-2021)“…Structure determination of membrane proteins is critical to the molecular understanding of many life processes, yet it has historically been a technically…”
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15
Olanzapine versus haloperidol in children with autistic disorder: an open pilot study
Published in Journal of the American Academy of Child and Adolescent Psychiatry (01-08-2001)“…Conventional neuroleptics ameliorate symptoms in children with autistic disorder; however, they are known to cause dyskinesias. Atypical neuroleptics,…”
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Structural basis of omega-3 fatty acid transport across the blood–brain barrier
Published in Nature (London) (08-07-2021)“…Docosahexaenoic acid is an omega-3 fatty acid that is essential for neurological development and function, and it is supplied to the brain and eyes…”
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Glutamate transporters have a chloride channel with two hydrophobic gates
Published in Nature (London) (11-03-2021)“…Glutamate is the most abundant excitatory neurotransmitter in the central nervous system, and its precise control is vital to maintain normal brain function…”
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Extracellular pH distribution in human tumours
Published in International journal of hyperthermia (1995)“…Extracellular pH (pHc) was determined by needle microelectrodes in 67 tumour nodules in 58 patients. The objective was to evaluate the relationship between…”
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Exhaled breath analysis using a carbon nanotube-based sensor array for metabolic and cardiovascular applications
Published in Heart, lung & circulation (2015)Get full text
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20
Nebulised antipseudomonal antibiotic therapy in cystic fibrosis: a meta-analysis of benefits and risks
Published in Thorax (01-04-1996)“…BACKGROUND: To establish the benefits and risks of nebulised antipseudomonal therapy in cystic fibrosis the results of relevant randomised controlled trials…”
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