Search Results - "Catchpole, Ryan J."

The Evolution of Reverse Gyrase Suggests a Nonhyperthermophilic Last Universal Common Ancestor by Catchpole, Ryan J, Forterre, Patrick

“…Abstract Reverse gyrase (RG) is the only protein found ubiquitously in hyperthermophilic organisms, but absent from mesophiles. As such, its simple presence or…”
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Selective degradation of phage RNAs by the Csm6 ribonuclease provides robust type III CRISPR immunity in Streptococcus thermophilus by Johnson, Katie A, Garrett, Sandra C, Noble-Molnar, Christopher, Elgarhi, Hanna A, Woodside, Walter T, Cooper, Clare, Zhang, Xinfu, Olson, Sara, Catchpole, Ryan J, Graveley, Brenton R, Terns, Michael P

“…Type III CRISPR immune systems bind viral or plasmid RNA transcripts and activate Csm3/Cmr4 and Cas10 nucleases to uniquely cleave both invader RNA and DNA,…”
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Characterisation of an Escherichia coli line that completely lacks ribonucleotide reduction yields insights into the evolution of parasitism and endosymbiosis by Arras, Samantha D M, Sibaeva, Nellie, Catchpole, Ryan J, Horinouchi, Nobuyuki, Si, Dayong, Rickerby, Alannah M, Deguchi, Kengo, Hibi, Makoto, Tanaka, Koichi, Takeuchi, Michiki, Ogawa, Jun, Poole, Anthony M

“…Life requires ribonucleotide reduction for de novo synthesis of deoxyribonucleotides. As ribonucleotide reduction has on occasion been lost in parasites and…”
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The Case for an Early Biological Origin of DNA by Poole, Anthony M., Horinouchi, Nobuyuki, Catchpole, Ryan J., Si, Dayong, Hibi, Makoto, Tanaka, Koichi, Ogawa, Jun

“…All life generates deoxyribonucleotides, the building blocks of DNA, via ribonucleotide reductases (RNRs). The complexity of this reaction suggests it did not…”
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Antibiotic genes spread far and wide by Catchpole, Ryan J, Poole, Anthony M

“…The genes responsible for antibiotics can spread between the three domains of life—Archaea, Bacteria and Eukaryotes…”
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New Type III CRISPR variant and programmable RNA targeting tool: Oh, thank heaven for Cas7-11 by Catchpole, Ryan J., Terns, Michael P.

“…Özcan et al. (2021) and van Beljouw et al. (2021) characterize a novel Type III-E CRISPR-Cas subtype, composed of a single polypeptide with crRNA processing…”
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Type III-A CRISPR systems as a versatile gene knockdown technology by Woodside, Walter T, Vantsev, Nikita, Catchpole, Ryan J, Garrett, Sandra C, Olson, Sara, Graveley, Brenton R, Terns, Michael P

“…CRISPR-Cas systems are functionally diverse prokaryotic antiviral defense systems, which encompass six distinct types (I-VI) that each encode different…”
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Hyper-stimulation of Pyrococcus furiosus CRISPR DNA uptake by a self-transmissible plasmid by Watts, Elizabeth A., Garrett, Sandra C., Catchpole, Ryan J., Clark, Landon M., Graveley, Brenton R., Terns, Michael P.

“…Pyrococcus furiosus is a hyperthermophilic archaeon with three effector CRISPR complexes (types I-A, I-B, and III-B) that each employ crRNAs derived from seven…”
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Circular replication-associated protein encoding DNA viruses identified in the faecal matter of various animals in New Zealand by Steel, Olivia, Kraberger, Simona, Sikorski, Alyssa, Young, Laura M., Catchpole, Ryan J., Stevens, Aaron J., Ladley, Jenny J., Coray, Dorien S., Stainton, Daisy, Dayaram, Anisha, Julian, Laurel, van Bysterveldt, Katherine, Varsani, Arvind

“…In recent years, innovations in molecular techniques and sequencing technologies have resulted in a rapid expansion in the number of known viral sequences, in…”
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A self-transmissible plasmid from a hyperthermophile that facilitates genetic modification of diverse Archaea by Catchpole, Ryan J., Barbe, Valérie, Magdelenat, Ghislaine, Marguet, Evelyne, Terns, Michael, Oberto, Jacques, Forterre, Patrick, Da Cunha, Violette

“…Conjugative plasmids are self-transmissible mobile genetic elements that transfer DNA between host cells via type IV secretion systems (T4SS). While…”
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Histones direct site-specific CRISPR spacer acquisition in model archaeon by Watts, Elizabeth A., Garrett, Sandra C., Catchpole, Ryan J., Clark, Landon M., Sanders, Travis J., Marshall, Craig J., Wenck, Breanna R., Vickerman, Robert L., Santangelo, Thomas J., Fuchs, Ryan, Robb, Brett, Olson, Sara, Graveley, Brenton R., Terns, Michael P.

“…CRISPR–Cas systems provide heritable immunity against viruses and other mobile genetic elements by incorporating fragments of invader DNA into the host CRISPR…”
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Disruption of quaternary structure in Escherichia coli dihydrodipicolinate synthase (DHDPS) generates a functional monomer that is no longer inhibited by lysine by Muscroft-Taylor, Andrew C., Catchpole, Ryan J., Dobson, Renwick C.J., Pearce, F. Grant, Perugini, Matthew A., Gerrard, Juliet A.

“…► Escherichia coli dihydrodipicolinate synthase monomer unit is catalytically active. ► Dihydrodipicolinate synthase dimer is the minimal unit for ( S)-lysine…”
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