Search Results - "Castrucci, A. M."

Environmental Control of Biological Rhythms: Effects on Development, Fertility and Metabolism by Amaral, F. G., Castrucci, A. M., Cipolla-Neto, J., Poletini, M. O., Mendez, N., Richter, H. G., Sellix, M. T.

“…Internal temporal organisation properly synchronised to the environment is crucial for health maintenance. This organisation is provided at the cellular level…”
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Novel light‐dependent and light‐independent functions of opsin 5 by Assis, L.V.M., Castrucci, A.M.L.

“…Linked Article: Lan et al. Br J Dermatol 2021; 185:391–404…”
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The effect of white light on normal and malignant murine melanocytes: A link between opsins, clock genes, and melanogenesis by de Assis, L.V.M., Moraes, M.N., da Silveira Cruz-Machado, S., Castrucci, A.M.L.

“…The skin possesses a photosensitive system comprised of opsins whose function is not fully understood, and clock genes which exert an important regulatory role…”
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High melatonin solubility in aqueous medium by Shida, C S, Castrucci, A M, Lamy-Freund, M T

“…The pineal hormone melatonin (5-methoxy-N-acetyl-tryptamine) has been reported to participate in important physiological processes. Although some of its…”
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Melanopsin Triggers the Release of Internal Calcium Stores in Response to Light by Kumbalasiri, T., Rollag, M. D., Isoldi, M. C., Castrucci, A. M. de Lauro, Provencio, I.

“…Melanopsin is the photopigment that confers photosensitivity upon intrinsically photosensitive retinal ganglion cells (ipRGCs). This subset of retinal ganglion…”
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Melanopsin (Opn4) Requirement for Normal Light-Induced Circadian Phase Shifting by Panda, Satchidananda, Sato, Trey K., Castrucci, Ana Maria, Rollag, Mark D., DeGrip, Willem J., Hogenesch, John B., Provencio, Ignacio, Kay, Steve A.

“…The master circadian oscillator in the hypothalamic suprachiasmatic nucleus is entrained to the day/night cycle by retinal photoreceptors. Melanopsin (Opn4),…”
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Melanopsin Is Required for Non-Image-Forming Photic Responses in Blind Mice by Panda, Satchidananda, Provencio, Ignacio, Tu, Daniel C., Pires, Susana S., Rollag, Mark D., Castrucci, Ana Maria, Pletcher, Mathew T., Sato, Trey K., Wiltshire, Tim, Andahazy, Mary, Kay, Steve A., Van Gelder, Russell N., Hogenesch, John B.

“…Although mice lacking rod and cone photoreceptors are blind, they retain many eye-mediated responses to light, possibly through photosensitive retinal ganglion…”
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Potent and prolonged-acting cyclic lactam analogs of .alpha.-melanotropin: design based on molecular dynamics by Al-Obeidi, Fahad, Castrucci, Ana M. de L, Hadley, Mac E, Hruby, Victor J

“…Utilizing results from previous structure-activity relationships and theoretical studies of alpha-melanotropin (alpha-MSH,…”
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The expression of melanopsin and clock genes in Xenopus laevis melanophores and their modulation by melatonin by Bluhm, A P C, Obeid, N N, Castrucci, A M L, Visconti, M A

“…Vertebrates have a central clock and also several peripheral clocks. Light responses might result from the integration of light signals by these clocks. The…”
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Adrenoceptors in normal and malignant human melanocytes by SCARPARO, A. C, VISCONTI, M. A, REIS DE OLIVEIRA, A, DE LAURO CASTRUCCI, A. M

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Modulation of rhodopsin gene expression and signaling mechanisms evoked by endothelins in goldfish and murine pigment cell lines by Lopes, G J D, Góis, C C, Lima, L H R G, Castrucci, A M L

“…Endothelins (ETs) and sarafotoxins (SRTXs) belong to a family of vasoconstrictor peptides, which regulate pigment migration and/or production in vertebrate…”
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Synthesis of a Cyclic Melanotropic Peptide Exhibiting Both Melanin-Concentrating and -Dispersing Activities by Wilkes, Brian C., Hruby, Victor J., A. M. De L. Castrucci, Sherbrooke, Wade C., Hadley, Mac E.

“…A putative melanin-concentrating hormone was synthesized. This peptide, H-Asp-Thr-Met-Arg-Cys-Met-Val-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Glu-Val-OH, stimulates…”
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Effects of continuous exposure to light on behavioral dopaminergic supersensitivity by Abı́lio, Vanessa C, Freitas, Fábio M, Dolnikoff, Miriam S, Castrucci, Ana Maria L, Filho, Roberto Frussa

“…Background: This study examines the effects of long-term continuous exposure to light on dopaminergic supersensitivity induced by repeated treatment with…”
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Comparative aspects of the pineal/melatonin system of poikilothermic vertebrates by Filadelfi, A M, Castrucci, A M

“…The pineal gland of poikilothermic vertebrates originates as an evagination from the diencephalic roof between the habenular and the posterior commissures, and…”
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Discovery of an alpha-melanotropin antagonist effective in vivo by Castrucci, A M, Sherbrooke, W C, Sawyer, T K, Staples, D J, Tuma, M C, Hadley, M E

“…A hybrid analogue, H-His-D-Arg-Ala-Trp-D-Phe-Lys-NH2, was designed based upon the primary structures of a growth hormone-releasing peptide analogue,…”
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alpha.-Melanotropin: the minimal active sequence in the frog skin bioassay by Hruby, Victor J, Wilkes, Brian C, Hadley, Mac E, Al-Obeidi, Fahad, Sawyer, Tomi K, Staples, Douglas J, DeVaux, Ann E, Dym, Orin, Castrucci, Ana Maria de L

“…The minimal sequence required for biological activity of alpha-MSH (alpha-melanotropin, alpha-melanocyte stimulating hormone) was determined in the frog (Rana…”
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Truncation studies of α-melanotropin peptides identify tripeptide analogues exhibiting prolonged agonist bioactivity by Haskell-Luevano, Carrie, Sawyer, Tomi K., Hendrata, Siska, North, Cheryl, Panahinia, Laila, Stum, Martha, Staples, Douglas J., De Lauro Castrucci, Anna M., Hadley, Mac E., Hruby, Victor J.

“…Systematic analysis of fragment derivatives of the superpotent α-MSH analogue, Ac-Ser-Tyr-Ser-Nle 4-Glu-His- dPhe 7-Arg-Trp-Gly-Lys-Pro-Val-NH 2 (NDP-MSH), led…”
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Differential structural requirements for the MSH and MCH activities of melanin concentrating hormone by Hadley, M E, Zechel, C, Wilkes, B C, Castrucci, A M, Visconti, M A, Pozo-Alonso, M, Hruby, V J

“…H-Asp-Thr-Met-Arg-Cys-Met-Val-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Glu-Val-OH , melanin concentrating hormone (MCH), exhibits both melanin granule concentrating and…”
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Melanotropin structure-activity studies on melanocytes of the teleost fish, Synbranchus marmoratus by Castrucci, A M, Hadley, M E, Wilkes, B C, Hruby, V J, Sawyer, T K

“…The minimal sequence of alpha-MSH required for full agonism on fish (Synbranchus marmoratus) melanocytes was determined to be Ac-alpha-MSH5-10-NH2 since…”
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Design of potent linear .alpha.-melanotropin 4-10-analogs modified in positions 5 and 10 by Al-Obeidi, Fahad, Hruby, Victor J, Castrucci, Ana M. de L, Hadley, Mac E

“…alpha-Melanocyte stimulating hormone (alpha-MSH) is a linear tridecapeptide (Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2) that has diverse…”
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