Search Results - "Castrogiovanni, Paola"
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The impact of physical activity on psychological health during Covid-19 pandemic in Italy
Published in Heliyon (01-06-2020)“…The worldwide spread of COVID-19 has upset the normality of Italian daily life, forcing population to social distancing and self-isolation. Since the…”
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Osteoarthritis in the XXIst century: risk factors and behaviours that influence disease onset and progression
Published in International Journal of Molecular Sciences (16-03-2015)“…Osteoarthritis (OA) is a growing public health problem across the globe, affecting more than half of the over 65 population. In the past, OA was considered a…”
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Moderate Physical Activity as a Prevention Method for Knee Osteoarthritis and the Role of Synoviocytes as Biological Key
Published in International journal of molecular sciences (25-01-2019)“…The purpose of this study was to investigate the influence of moderate physical activity (MPA) on the expression of osteoarthritis (OA)-related (IL-1β, IL-6,…”
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CHI3L2 Expression Levels Are Correlated with AIF1, PECAM1, and CALB1 in the Brains of Alzheimer’s Disease Patients
Published in Journal of molecular neuroscience (01-10-2020)“…Alzheimer’s disease (AD) represents one of the main forms of dementia that afflicts our society. The expression of several genes has been associated with…”
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Biomarkers of Chondrocyte Apoptosis and Autophagy in Osteoarthritis
Published in International journal of molecular sciences (31-08-2015)“…Cell death with morphological and molecular features of apoptosis has been detected in osteoarthritic (OA) cartilage, which suggests a key role for chondrocyte…”
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Apoptosis and Autophagy in the Pathogenesis of Osteoarthritis
Published in Journal of investigative surgery (20-10-2020)Get full text
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Nutraceutical Supplements in the Management and Prevention of Osteoarthritis
Published in International journal of molecular sciences (06-12-2016)“…Nutraceuticals are dietary compounds which have a role in the balance of anabolic and catabolic signals in joints. Their regulatory function on homeostasis of…”
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Physical activity and Mediterranean diet based on olive tree phenolic compounds from two different geographical areas have protective effects on early osteoarthritis, muscle atrophy and hepatic steatosis
Published in European journal of nutrition (01-03-2019)“…Purpose Osteoarthitis (OA) leads to progressive loss of articular cartilage, pain and joint disability. An acute injury constitutes an important risk factor…”
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Extra-virgin olive oil diet and mild physical activity prevent cartilage degeneration in an osteoarthritis model: an in vivo and in vitro study on lubricin expression
Published in The Journal of nutritional biochemistry (01-12-2013)“…Mediterranean diet includes a relatively high fat consumption mostly from monounsaturated fatty acids mainly provided by olive oil, the principal source of…”
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GNG13 Is a Potential Marker of the State of Health of Alzheimer’s Disease Patients’ Cerebellum
Published in Journal of molecular neuroscience (01-05-2021)“…Brain regions such as the cerebellum (CB) have been neglected for a long time in the study of Alzheimer’s disease (AD) pathogenesis. In reference to a new…”
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Impact of Western and Mediterranean Diets and Vitamin D on Muscle Fibers of Sedentary Rats
Published in Nutrients (17-02-2018)“…The metabolic syndrome is associated with sarcopenia. Decreased serum levels of Vitamin D (VitD) and insulin-like growth factor (IGF)-1 and their mutual…”
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Assessment of Vitamin D Supplementation on Articular Cartilage Morphology in a Young Healthy Sedentary Rat Model
Published in Nutrients (03-06-2019)“…Deficiency in vitamin D (Vit D) has been widely associated with several musculoskeletal diseases. However, the effects of the exogenous Vit D supplementation…”
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Co-Expression and Co-Localization of Cartilage Glycoproteins CHI3L1 and Lubricin in Osteoarthritic Cartilage: Morphological, Immunohistochemical and Gene Expression Profiles
Published in International journal of molecular sciences (11-03-2016)“…Osteoarthritis is the most common human arthritis characterized by degeneration of articular cartilage. Several studies reported that levels of human cartilage…”
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Resistin-like beta reduction is associated to low survival rate and is downregulated by adjuvant therapy in colorectal cancer patients
Published in Scientific reports (27-01-2023)“…Colorectal Cancer (CRC) is one of the most common cancers accounting for 1.8 million new cases worldwide every year. Therefore, the identification of new…”
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Post-traumatic caspase-3 expression in the adjacent areas of growth plate injury site: a morphological study
Published in International journal of molecular sciences (29-07-2013)“…The epiphyseal plate is a hyaline cartilage plate that sits between the diaphysis and the epiphysis. The objective of this study was to determine the impact of…”
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The Synovium Theory: Can Exercise Prevent Knee Osteoarthritis? The Role of "Mechanokines", A Possible Biological Key
Published in Journal of functional morphology and kinesiology (23-01-2019)“…Osteoarthritis (OA) is a debilitating disease widespread in the world, having a negative impact on daily activities, especially in old age [...]…”
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Evaluation of a Cell-Free Collagen Type I-Based Scaffold for Articular Cartilage Regeneration in an Orthotopic Rat Model
Published in Materials (21-05-2020)“…The management of chondral defects represents a big challenge because of the limited self-healing capacity of cartilage. Many approaches in this field obtained…”
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Sex, Age, and Regional Differences in CHRM1 and CHRM3 Genes Expression Levels in the Human Brain Biopsies: Potential Targets for Alzheimer's Disease-related Sleep Disturbances
Published in Current neuropharmacology (01-01-2023)“…Background: Cholinergic hypofunction and sleep disturbance are hallmarks of Alzheimer’s disease (AD), a progressive disorder leading to neuronal deterioration…”
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Expression of the OAS Gene Family Is Highly Modulated in Subjects Affected by Juvenile Dermatomyositis, Resembling an Immune Response to a dsRNA Virus Infection
Published in International journal of molecular sciences (17-09-2018)“…Juvenile dermatomyositis (JDM) is a systemic, autoimmune, interferon (IFN)-mediated inflammatory muscle disorder that affects children younger than 18 years of…”
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Runx2 mediated Induction of Novel Targets ST2 and Runx3 Leads to Cooperative Regulation of Hypertrophic Differentiation in ATDC5 Chondrocytes
Published in Scientific reports (20-12-2017)“…Knowledge concerning expression and function of Suppression of Tumorigenicity 2 (ST2) in chondrocytes is at present, limited. Analysis of murine growth plates…”
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