Search Results - "Castro Velazco, Jorge"

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    Immunogenicity profile in African green monkeys of a vaccine candidate based on a mutated form of human Interleukin-15 by Rodríguez-Álvarez, Yunier, Batista-Roche, Lino Gerardo, Llopiz-Arzuaga, Alexey, Puente-Pérez, Pedro, Martínez-Castillo, Rafael, Castro-Velazco, Jorge, Santos-Savio, Alicia

    Published in BMC immunology (18-12-2021)
    “…Interleukin (IL)-15 is a proinflammatory T-cell growth factor overexpressed in several autoimmune diseases such as rheumatoid arthritis. Our initial strategy…”
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    Journal Article
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    Immunogenicity and some safety features of a VEGF-based cancer therapeutic vaccine in rats, rabbits and non-human primates by Morera, Yanelys, Bequet-Romero, Mónica, Ayala, Marta, Velazco, Jorge Castro, Pérez, Pedro Puente, Alba, Jesús Suárez, Ancizar, Julio, Rodríguez, Meilyn, Cosme, Karelia, Gavilondo, Jorge V

    Published in Vaccine (26-04-2010)
    “…Abstract We have developed a cancer vaccine candidate (hereafter denominated CIGB-247), based on recombinant modified human vascular endothelial growth factor…”
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    Experimental studies of a vaccine formulation of recombinant human VEGF antigen with aluminum phosphate by Pérez Sánchez, Lincidio, Morera Díaz, Yanelys, Bequet-Romero, Mónica, Ramses Hernández, Gerardo, Rodríguez, Yadira, Castro Velazco, Jorge, Puente Pérez, Pedro, Ayala Avila, Marta, Gavilondo, Jorge V

    Published in Human vaccines & immunotherapeutics (03-08-2015)
    “…CIGB-247 is a cancer vaccine that is a formulation of a recombinant protein antigen representative of the human vascular endothelial growth factor (VEGF) with…”
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    Application of a colorimetric CTLL-2 cell proliferation assay for the evaluation of IL-15 antagonists by Yunier Rodríguez-Álvarez, Haydee Gerónimo-Pérez, Hilda Garay-Pérez, Jorge Castro-Velazco, Gerardo García-Illera, Alicia Santos-Savio

    “…Dysregulated expression of Interleukin (IL)-15 has been associated to several autoimmune and inflammatory diseases. In this sense, some agents that inhibit…”
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