Search Results - "Castro Velazco, Jorge"
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Screening for immune response against Dengue virus in Vietnamese non‐human primates: implications for vaccine developers
Published in Clinical & translational immunology (01-03-2017)“…One of the major problems faced for the development of a vaccine against Dengue virus is the lack of a suitable animal model. Although non‐human primates do…”
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Immunogenicity profile in African green monkeys of a vaccine candidate based on a mutated form of human Interleukin-15
Published in BMC immunology (18-12-2021)“…Interleukin (IL)-15 is a proinflammatory T-cell growth factor overexpressed in several autoimmune diseases such as rheumatoid arthritis. Our initial strategy…”
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Immunogenicity and some safety features of a VEGF-based cancer therapeutic vaccine in rats, rabbits and non-human primates
Published in Vaccine (26-04-2010)“…Abstract We have developed a cancer vaccine candidate (hereafter denominated CIGB-247), based on recombinant modified human vascular endothelial growth factor…”
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Experimental studies of a vaccine formulation of recombinant human VEGF antigen with aluminum phosphate
Published in Human vaccines & immunotherapeutics (03-08-2015)“…CIGB-247 is a cancer vaccine that is a formulation of a recombinant protein antigen representative of the human vascular endothelial growth factor (VEGF) with…”
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Active immunization with human interleukin-15 induces neutralizing antibodies in non-human primates
Published in BMC immunology (26-09-2016)“…Interleukin-15 is an immunostimulatory cytokine overexpressed in several autoimmune and inflammatory diseases such as Rheumatoid Arthritis, psoriasis and…”
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Application of a colorimetric CTLL-2 cell proliferation assay for the evaluation of IL-15 antagonists
Published in Biotecnología Aplicada“…Dysregulated expression of Interleukin (IL)-15 has been associated to several autoimmune and inflammatory diseases. In this sense, some agents that inhibit…”
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