Search Results - "Castro De Moura, Manuel"

Identification of an Immune-specific Class of Hepatocellular Carcinoma, Based on Molecular Features by Sia, Daniela, Jiao, Yang, Martinez-Quetglas, Iris, Kuchuk, Olga, Villacorta-Martin, Carlos, Castro de Moura, Manuel, Putra, Juan, Camprecios, Genis, Bassaganyas, Laia, Akers, Nicholas, Losic, Bojan, Waxman, Samuel, Thung, Swan N, Mazzaferro, Vincenzo, Esteller, Manel, Friedman, Scott L, Schwartz, Myron, Villanueva, Augusto, Llovet, Josep M

“…Abstract Background and Aims Agents that induce an immune response against tumors by altering T-cell regulation have increased survival times of patients with…”
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The transcribed pseudogene RPSAP52 enhances the oncofetal HMGA2-IGF2BP2-RAS axis through LIN28B-dependent and independent let-7 inhibition by Oliveira-Mateos, Cristina, Sánchez-Castillo, Anaís, Soler, Marta, Obiols-Guardia, Aida, Piñeyro, David, Boque-Sastre, Raquel, Calleja-Cervantes, Maria E., Castro de Moura, Manuel, Martínez-Cardús, Anna, Rubio, Teresa, Pelletier, Joffrey, Martínez-Iniesta, Maria, Herrero-Martín, David, Tirado, Oscar M., Gentilella, Antonio, Villanueva, Alberto, Esteller, Manel, Farré, Lourdes, Guil, Sonia

“…One largely unknown question in cell biology is the discrimination between inconsequential and functional transcriptional events with relevant regulatory…”
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Correction: Entamoeba lysyl-tRNA Synthetase Contains a Cytokine-Like Domain with Chemokine Activity towards Human Endothelial Cells by de Moura, Manuel Castro, Miro, Francesc, Han, Jung Min, Kim, Sunghoon, Celada, Antonio, de Pouplana, Lluís Ribas

“…[This corrects the article DOI: 10.1371/journal.pntd.0001398.]…”
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Cellular and clinical impact of protein phosphatase enzyme epigenetic silencing in multiple cancer tissues by Wiltshire, Edward, de Moura, Manuel Castro, Piñeyro, David, Joshi, Ricky S

“…Protein Phosphatase Enzymes (PPE) and protein kinases simultaneously control phosphorylation mechanisms that tightly regulate intracellular signalling pathways…”
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Resistance to PI3Kδ inhibitors in marginal zone lymphoma can be reverted by targeting the IL-6/PDGFRA axis by Arribas, Alberto J., Napoli, Sara, Cascione, Luciano, Sartori, Giulio, Barnabei, Laura, Gaudio, Eugenio, Tarantelli, Chiara, Mensah, Afua Adjeiwaa, Spriano, Filippo, Zucchetto, Antonella, Rossi, Francesca M, Rinaldi, Andrea, Castro de Moura, Manuel, Jovic, Sandra, Bordone-Pittau, Roberta, Di Veroli, Alessandra, Stathis, Anastasios, Cruciani, Gabriele, Stussi, Georg, Gattei, Valter, Brown, Jennifer R., Esteller, Manel, Zucca, Emanuele, Rossi, Davide, Bertoni, Francesco

“…PI3Kδ inhibitors are active in patients with lymphoid neoplasms and a first series of them have been approved for the treatment of multiple types of B-cell…”
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Analysis of gene expression changes in peach leaves in response to Plum pox virus infection using RNA‐Seq by Rubio, Manuel, Rodríguez‐Moreno, Luis, Ballester, Ana Rosa, Moura, Manuel Castro, Bonghi, Claudio, Candresse, Thierry, Martínez‐Gómez, Pedro

“…Differences in gene expression were studied after Plum pox virus (PPV, sharka disease) infection in peach GF305 leaves with and without sharka symptoms using…”
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The transcribed ultraconserved region uc.160+ enhances processing and A‐to‐I editing of the miR‐376 cluster: hypermethylation improves glioma prognosis by Soler, Marta, Davalos, Veronica, Sánchez‐Castillo, Anaís, Mora‐Martinez, Carlos, Setién, Fernando, Siqueira, Edilene, Castro de Moura, Manuel, Esteller, Manel, Guil, Sonia

“…Transcribed ultraconserved regions (T‐UCRs) are noncoding RNAs derived from DNA sequences that are entirely conserved across species. Their expression is…”
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Gene Expression Analysis of Plum pox virus (Sharka) Susceptibility/Resistance in Apricot (Prunus armeniaca L.) by Rubio, Manuel, Ballester, Ana Rosa, Olivares, Pedro Manuel, Castro de Moura, Manuel, Dicenta, Federico, Martínez-Gómez, Pedro

“…RNA-Seq has proven to be a very powerful tool in the analysis of the Plum pox virus (PPV, sharka disease)/Prunus interaction. This technique is an important…”
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MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer by Mattesen, Trine B., Rasmussen, Mads H., Sandoval, Juan, Ongen, Halit, Árnadóttir, Sigrid S., Gladov, Josephine, Martinez-Cardus, Anna, Castro de Moura, Manuel, Madsen, Anders H., Laurberg, Søren, Dermitzakis, Emmanouil T., Esteller, Manel, Andersen, Claus L., Bramsen, Jesper B.

“…Transcriptional characterization and classification has potential to resolve the inter-tumor heterogeneity of colorectal cancer and improve patient management…”
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Publisher Correction: MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer by Mattesen, Trine B., Rasmussen, Mads H., Sandoval, Juan, Ongen, Halit, Árnadóttir, Sigrid S., Gladov, Josephine, Martinez-Cardus, Anna, de Moura, Manuel Castro, Madsen, Anders H., Laurberg, Søren, Dermitzakis, Emmanouil T., Esteller, Manel, Andersen, Claus L., Bramsen, Jesper B.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Extramedullary multiple myeloma patient-derived orthotopic xenograft with a highly altered genome: combined molecular and therapeutic studies by Farre, Lourdes, Sanz, Gabriela, Ruiz-Xivillé, Neus, Castro de Moura, Manuel, Martin-Tejera, Juan Francisco, Gonçalves-Ribeiro, Samuel, Martinez-Iniesta, Maria, Calaf, Monica, Luis Mosquera, Jose, Martín-Subero, José Ignacio, Granada, Isabel, Esteller, Manel, Domingo-Domenech, Eva, Climent, Fina, Villanueva, Alberto, Sureda, Anna

“…Extramedullary multiple myeloma (EMM) has an overall survival of 6 months and occurs in 20% of multiple myeloma (MM) patients. Genetic and epigenetic…”
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Bromodomain inhibition shows antitumoral activity in mice and human luminal breast cancer by Pérez-Salvia, Montserrat, Simó-Riudalbas, Laia, Llinàs-Arias, Pere, Roa, Laura, Setien, Fernando, Soler, Marta, de Moura, Manuel Castro, Bradner, James E, Gonzalez-Suarez, Eva, Moutinho, Catia, Esteller, Manel

“…BET bromodomain inhibitors, which have an antitumoral effect against various solid cancer tumor types, have not been studied in detail in luminal breast…”
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Physical Activity and Genome-wide DNA Methylation: The REgistre GIroní del COR Study by FERNÁNDEZ-SANLÉS, ALBA, SAYOLS-BAIXERAS, SERGI, CASTRO DE MOURA, MANUEL, ESTELLER, MANEL, SUBIRANA, ISAAC, TORRES-CUEVAS, SEBASTIÁN, PÉREZ-FERNÁNDEZ, SILVIA, ASLIBEKYAN, STELLA, MARRUGAT, JAUME, ELOSUA, ROBERTO

“…INTRODUCTIONDNA methylation may be one of the biological mechanisms underlying the health benefits of physical activity (PA). Our objective was to determine…”
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Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis by Moran, Sebastian, MSc, Martínez-Cardús, Anna, PhD, Sayols, Sergi, MSc, Musulén, Eva, MD, Balañá, Carme, MD, Estival-Gonzalez, Anna, MD, Moutinho, Cátia, PhD, Heyn, Holger, PhD, Diaz-Lagares, Angel, PhD, de Moura, Manuel Castro, MSc, Stella, Giulia M, MD, Comoglio, Paolo M, Prof, Ruiz-Miró, Maria, PhD, Matias-Guiu, Xavier, MD, Pazo-Cid, Roberto, MD, Antón, Antonio, MD, Lopez-Lopez, Rafael, MD, Soler, Gemma, MD, Longo, Federico, MD, Guerra, Isabel, MD, Fernandez, Sara, MD, Assenov, Yassen, PhD, Plass, Christoph, Prof, Morales, Rafael, MD, Carles, Joan, MD, Bowtell, David, Prof, Mileshkin, Linda, MD, Sia, Daniela, PhD, Tothill, Richard, PhD, Tabernero, Josep, MD, Llovet, Josep M, Prof, Esteller, Manel, Prof

“…Summary Background Cancer of unknown primary ranks in the top ten cancer presentations and has an extremely poor prognosis. Identification of the primary…”
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Entamoeba lysyl-tRNA synthetase contains a cytokine-like domain with chemokine activity towards human endothelial cells by Castro de Moura, Manuel, Miro, Francesc, Han, Jung Min, Kim, Sunghoon, Celada, Antonio, Ribas de Pouplana, Lluís

“…Immunological pressure encountered by protozoan parasites drives the selection of strategies to modulate or avoid the immune responses of their hosts. Here we…”
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Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment by Wheeler, David A., Takebe, Naoko, Hinoue, Toshinori, Hoadley, Katherine A., Cardenas, Maria F., Hamilton, Alina M., Laird, Peter W., Wang, Linghua, Johnson, Adrienne, Dewal, Ninad, Miller, Vincent, Piñeyro, David, Castro de Moura, Manuel, Esteller, Manel, Shen, Hui, Zenklusen, Jean Claude, Tarnuzzer, Roy, McShane, Lisa M., Tricoli, James V., Williams, Paul M., Lubensky, Irina, O'Sullivan-Coyne, Geraldine, Kohn, Elise C., Little, Richard F., White, Jeffrey, Malik, Shakun, Harris, Lyndsay, Weil, Carol, Chen, Alice P., Karlovich, Chris, Rodgers, Brian, Shankar, Lalitha, Jacobs, Paula, Nolan, Tracy, Hu, Jianhong, Muzny, Donna M., Doddapaneni, Harshavardhan, Korchina, Viktoriya, Gastier-Foster, Julie, Bowen, Jay, Leraas, Kristen, Edmondson, Elijah F., Doroshow, James H., Conley, Barbara A., Ivy, S. Percy, Staudt, Louis M.

“…A small fraction of cancer patients with advanced disease survive significantly longer than patients with clinically comparable tumors. Molecular mechanisms…”
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The DNA methylation landscape of human cancer organoids available at the American type culture collection by Joshi, Ricky, Castro De Moura, Manuel, Piñeyro, David, Alvarez-Errico, Damiana, Arribas, Carles, Esteller, Manel

“…One caveat in cancer research is the dependence of certain experimental systems that might not really reflect the properties of the primary tumours. The recent…”
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Circular RNA CpG island hypermethylation-associated silencing in human cancer by Ferreira, Humberto J, Davalos, Veronica, de Moura, Manuel Castro, Soler, Marta, Perez-Salvia, Montserrat, Bueno-Costa, Alberto, Setien, Fernando, Moran, Sebastian, Villanueva, Alberto, Esteller, Manel

“…Noncoding RNAs (ncRNAs), such as microRNAs and long noncoding RNAs (lncRNAs), participate in cellular transformation. Work done in the last decade has also…”
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In vivo conditional deletion of HDAC7 reveals its requirement to establish proper B lymphocyte identity and development by Azagra, Alba, Román-González, Lidia, Collazo, Olga, Rodríguez-Ubreva, Javier, de Yébenes, Virginia G, Barneda-Zahonero, Bruna, Rodríguez, Jairo, Castro de Moura, Manuel, Grego-Bessa, Joaquim, Fernández-Duran, Irene, Islam, Abul B M M K, Esteller, Manel, Ramiro, Almudena R, Ballestar, Esteban, Parra, Maribel

“…Class IIa histone deacetylase (HDAC) subfamily members are tissue-specific gene repressors with crucial roles in development and differentiation processes. A…”
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DNA methylation of MMPs and TIMPs in atherothrombosis process in carotid plaques and blood tissues by Gallego-Fabrega, Cristina, Cullell, Natalia, Soriano-Tárraga, Carolina, Carrera, Caty, Torres-Aguila, Nuria P, Muiño, Elena, Cárcel-Márquez, Jara, de Moura, Manuel Castro, Fernández-Sanlés, Alba, Esteller, Manel, Elosua, Roberto, Jiménez-Conde, Jordi, Roquer, Jaume, Montaner, Joan, Krupinski, Jerzy, Fernandez-Cadenas, Israel

“…Polymorphisms and serum levels of Matrix Metalloproteinases (MMP) and Tissue Inhibitor of Metalloproteinases (TIMP) have been studied with regard to…”
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