Search Results - "Castro‐Junior, Gilberto"
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Molecular basis of oral squamous cell carcinoma in young patients: Is it any different from older patients?
Published in Journal of oral pathology & medicine (01-07-2018)“…Oral squamous cell carcinoma (OSCC) is the commonest subtype of oral cancer, mainly affecting older patients. It used to be a rare disease among individuals…”
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Head and neck surgery recommendations during the COVID-19 pandemic
Published in The lancet oncology (01-09-2020)Get full text
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Cushing's syndrome due to ectopic adrenocorticotropin secretion by a parotid carcinoma
Published in Archives of Endocrinology and Metabolism (01-01-2022)“…We report a rare case of Cushing's syndrome in a 37-year-old female who initially presented with localized acinic cell carcinoma of the parotid gland. In…”
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Tumor glycolytic profiling through 18F-FDG PET/CT predicts immune checkpoint inhibitor efficacy in advanced NSCLC
Published in Therapeutic advances in medical oncology (01-01-2022)“…Background: A significant proportion of patients with non-small-cell lung cancer (NSCLC) do not respond to immune checkpoint inhibitors (ICIs). Since metabolic…”
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Postradiation Matrix Metalloproteinase-20 Expression and Its Impact on Dental Micromorphology and Radiation-Related Caries
Published in Caries research (01-01-2017)“…Recent evidence suggests that head-and-neck radiotherapy (HNRT) increases active forms of matrix metalloproteinase-20 (MMP-20) in human tooth crowns, degrading…”
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Effect of the COVID-19 Pandemic on the Activity of Physicians Working in the Areas of Head and Neck Surgery and Otorhinolaryngology
Published in International Archives of Otorhinolaryngology (01-07-2020)“…Abstract Introduction Coronavirus disease 2019 (COVID-19) is an acute infection caused by the new coronavirus (SARS-CoV-2) and it is highly transmissible,…”
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Identifying activating mutations in the EGFR gene: prognostic and therapeutic implications in non-small cell lung cancer
Published in Jornal brasileiro de pneumologia (01-07-2015)“…Lung cancer is the leading cause of cancer-related deaths worldwide. Promising new therapies have recently emerged from the development of molecular targeted…”
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The importance of molecular characterization in lung cancer
Published in Jornal brasileiro de pneumologia (2019)Get full text
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Induction Chemotherapy for Advanced Oral Cavity Cancer
Published in Current oncology reports (01-11-2021)“…Purpose of Review Head and neck cancer is a heterogeneous disease, comprising multiple subsites with diverse etiologic factors, pathology and molecular…”
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Effectiveness of COVID-19 vaccines against severe COVID-19 among patients with cancer in Catalonia, Spain
Published in Nature communications (19-06-2024)“…Patients with cancer were excluded from pivotal randomized clinical trials of COVID-19 vaccine products, and available observational evidence on vaccine…”
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Sotorasib (960 mg or 240 mg) once daily in patients with previously treated KRAS G12C-mutated advanced NSCLC
Published in European journal of cancer (1990) (01-09-2024)“…Sotorasib 960 mg once daily is approved to treat KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC). Sotorasib exhibits…”
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BRAF‐V600E expression correlates with ameloblastoma aggressiveness
Published in Histopathology (01-02-2017)“…Aims The aim of this study was to investigate whether the expression of BRAF‐V600E determines an aggressive clinical and molecular presentation of…”
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Physical performance and plasma metabolic profile as potential prognostic factors in metastatic lung cancer patients
Published in European journal of clinical investigation (01-11-2024)“…Low physical performance is associated with higher mortality rate in multiple pathological conditions. Here, we aimed to determine whether body composition and…”
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Survival inequalities in head and neck cancers: A hospital‐based cohort study
Published in Head & neck (01-09-2023)“…Background We investigated whether the socioeconomic status (SES) influenced survival rates in oropharynx cancers (OPC), oral cavity cancers (OCC), and larynx…”
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Cephaeline is an inductor of histone H3 acetylation and inhibitor of mucoepidermoid carcinoma cancer stem cells
Published in Journal of oral pathology & medicine (01-07-2022)“…Aim To evaluate the potential use of Cephaeline as a therapeutic strategy to manage mucoepidermoid carcinomas (MEC) of the salivary glands. Material and…”
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Complete pathologic response as a prognostic factor for squamous cell carcinoma of the oropharynx post-chemoradiotherapy
Published in Brazilian journal of otorhinolaryngology (01-09-2015)“…Chemoradiotherapy for squamous cell carcinoma of the oropharynx (SCCO) provides good results for locoregional disease control, with high rates of complete…”
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Young head and neck cancer patients are at increased risk of developing oral mucositis and trismus
Published in Supportive care in cancer (01-09-2020)“…Objectives To evaluate cancer treatment–related toxicities in young head and neck cancer (HNC) patients. Material and methods A total of 44 patients were…”
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Lung Cancer and the COVID-19 pandemic: Recommendations from the Brazilian Thoracic Oncology Group
Published in Clinics (São Paulo, Brazil) (01-01-2020)“…New cases of the novel coronavirus disease 2019 (COVID-19), also known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continue to rise…”
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The role of single-nucleotide polymorphism (SNPs) in toxicity of induction chemotherapy based on cisplatin and paclitaxel in patients with advanced head and neck cancer
Published in Oral oncology (01-11-2019)“…AbstractBackgroundInduction chemotherapy in locally-advanced head and neck squamous cell carcinoma (LAHNSCC) patients is potentially associated to serious…”
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De-escalation treatment of human papillomavirus-positive oropharyngeal squamous cell carcinoma: an evidence-based review for the locally advanced disease
Published in Current opinion in oncology (01-05-2018)“…PURPOSE OF REVIEWOropharyngeal cancer (OPC) incidence is increasing worldwide, especially in developed countries where it seems to be etiologically related to…”
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