Search Results - "Castro, Ricardo A. E."
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Coamorphous Systems of Valsartan: Thermal Analysis Contribution to Evaluate Intermolecular Interactions Effects on the Structural Relaxation
Published in Molecules (Basel, Switzerland) (25-08-2023)“…Coamorphous formation in binary systems of valsartan (Val) with 4,4′-bipyridine (Bipy) and trimethoprim (Tri) was investigated for mixtures with a mole…”
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Recycling Ophthalmic Lens Wastewater in a Circular Economy Context: A Case Study with Microalgae Integration
Published in Materials (22-12-2023)“…Water pollution poses a global threat to ecosystems and human health and is driven by the presence of various contaminants in wastewater, including nano- and…”
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3
Naproxen Cocrystals with Pyridinecarboxamide Isomers
Published in Crystal growth & design (07-12-2011)“…A screening of naproxen cocrystals with coformers picolinamide, nicotinamide, isonicotinamide, and pyrazinamide is performed by the Kofler contact method and…”
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Trimethoprim-Based multicomponent solid Systems: Mechanochemical Screening, characterization and antibacterial activity assessment
Published in International journal of pharmaceutics (15-08-2024)“…[Display omitted] In this work, multicomponent trimethoprim-based pharmaceutical solid systems were developed by mechanochemistry, using coformers from the…”
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5
Dihydrofolate Reductase Inhibitors: The Pharmacophore as a Guide for Co-Crystal Screening
Published in Molecules (Basel, Switzerland) (06-11-2021)“…In this work, co-crystal screening was carried out for two important dihydrofolate reductase (DHFR) inhibitors, trimethoprim (TMP) and pyrimethamine (PMA), and…”
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Thermal studies, degradation kinetic, equilibrium solubility, DFT, MIR, and XRPD analyses of a new cocrystal of gemfibrozil and isonicotinamide
Published in Journal of thermal analysis and calorimetry (01-06-2019)“…A synthesis of a novel pharmaceutical cocrystal of the gemfibrozil (GEM) with the isonicotinamide (INCT) as coformer was carried out using the mechanochemical…”
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7
Binary phase diagrams of pyridinecarboxamide isomers
Published in Journal of thermal analysis and calorimetry (01-12-2017)“…Pyridinecarboxamide binary phase diagrams have been established using differential scanning calorimetry, infrared spectroscopy and X-ray powder diffraction…”
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β-Phase Formation of Poly(9,9-dioctylfluorene) Induced by Liposome Phospholipid Bilayers
Published in The journal of physical chemistry. B (19-05-2011)“…The well-structured β-phase emission of the neutral poly(9,9-dioctylfluorene) (PFO) is observed in 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) bilayers,…”
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9
A quality by design framework for developing nanocrystal bioenabling formulations
Published in International journal of pharmaceutics (05-11-2023)“…[Display omitted] The present study aims to outline a rational framework for the design and development of a 1.0% (w/v) hydrocortisone nanocrystal-based…”
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Norfloxacin Cocrystals: Mechanochemical Synthesis and Scale-up Viability Through Solubility Studies
Published in Journal of pharmaceutical sciences (01-08-2023)“…Cocrystals are recognized as one of the most efficient approaches to improve aqueous solubility of Biopharmaceutical Classification System, BCS, classes II and…”
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Polymorphic Cocrystals of the Antimalarial Drug Pyrimethamine: Two Case Studies
Published in Crystal growth & design (07-07-2021)“…Polymorphism is known to have significant implications in the pharmaceutical industry. However, there are relatively few studies of polymorphic pharmaceutical…”
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At-line green synthesis monitoring of new pharmaceutical co-crystals lamivudine:theophylline polymorph I and II, quantification of polymorph I among its APIs using FT-IR spectroscopy and MCR-ALS
Published in Journal of pharmaceutical and biomedical analysis (30-05-2019)“…•Two new pharmaceutical co-crystal lamivudine:theophylline polymorphs I and II are synthetized.•Application of FT-IR spectroscopy with MCR-ALS as an at-line…”
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Physicochemical, Thermal, Crystallographic, and Morphological Properties of Biodynamic Black Rice Starch, and of Residual Fractions From Aqueous Extraction
Published in Starch - Stärke (01-11-2018)“…The physicochemical, thermal, crystallographic, and morphological properties of biodynamic black rice starch, and of the residual fractions from aqueous…”
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Lamotrigine: Design and synthesis of new multicomponent solid forms
Published in European journal of pharmaceutical sciences (01-03-2019)“…In this work, a crystal engineering and thermodynamic based approach has been used aiming at contributing to a deeper knowledge of lamotrigine multicomponent…”
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Synthesis, physicochemical and optical properties of bis-thiosemicarbazone functionalized graphene oxide
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-01-2018)“…Fluorescent materials are important for low-cost opto-electronic and biomedical sensor devices. In this study we present the synthesis and characterization of…”
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A thermodynamic based approach on the investigation of a diflunisal pharmaceutical co-crystal with improved intrinsic dissolution rate
Published in International journal of pharmaceutics (15-05-2014)“…[Display omitted] A thermodynamic based approach is used to investigate diflunisal+nicotinamide binary and solution mixtures. A 2:1 co-crystal could be…”
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Pyrazinamide-Diflunisal: A New Dual-Drug Co-Crystal
Published in Crystal growth & design (02-11-2011)“…A 1:1 co-crystal involving pyrazinamide, one of the first-line drugs recommended by the World Health Organization for tuberculosis treatment, and diflunisal, a…”
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A New Insight into Pyrazinamide Polymorphic Forms and their Thermodynamic Relationships
Published in Crystal growth & design (06-01-2010)“…Screening of pyrazinamide polymorphs was carried out by crystallization from solvents differing in polarity and hydrogen bonding ability and also by…”
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The structure of betaxolol studied by infrared spectroscopy and natural bond orbital theory
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (01-08-2010)“…Betaxolol is a selective β 1 receptor blocker used in the treatment of hypertension and glaucoma. A study of the betaxolol structure based on infrared…”
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20
Polymorphism of trans-1,4-Cyclohexanediol: Conformational Isomorphism
Published in Crystal growth & design (03-03-2010)“…In this work, an investigation on the polymorphism of trans-1,4-cyclohexanediol is performed. Polymorph screening is carried out by crystallization from…”
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