Search Results - "Castro, Lizbeth Perez"
-
1
Tryptophan and its metabolites in normal physiology and cancer etiology
Published in The FEBS journal (01-01-2023)“…Within the growing field of amino acid metabolism, tryptophan (Trp) catabolism is an area of increasing interest. Trp is essential for protein synthesis, and…”
Get full text
Journal Article -
2
Targeting of neuroblastoma cells through Kynurenine-AHR pathway inhibition
Published in The FEBS journal (01-05-2024)“…Neuroblastoma poses significant challenges in clinical management. Despite its relatively low incidence, this malignancy contributes disproportionately to…”
Get full text
Journal Article -
3
Characterizing the transcriptional signature regulated by the AHR ligands TCDD and kynurenine in colon cancer cells
Published in The FASEB journal (01-05-2022)“…AHR was first identified as the receptor that binds to the pollutant TCDD, which causes tumorigenesis. Since its identification, AHR has been credited to play…”
Get full text
Journal Article -
4
MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer
Published in Genes & development (01-09-2019)“…Tumors display increased uptake and processing of nutrients to fulfill the demands of rapidly proliferating cancer cells. Seminal studies have shown that the…”
Get full text
Journal Article -
5
Tryptophan fuels MYC-dependent liver tumorigenesis through indole 3-pyruvate synthesis
Published in Nature communications (20-05-2024)“…Cancer cells exhibit distinct metabolic activities and nutritional dependencies compared to normal cells. Thus, characterization of nutrient demands by…”
Get full text
Journal Article -
6
First person – Lizbeth Perez-Castro and Niranjan Venkateswaran
Published in Journal of cell science (01-10-2022)“…ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping researchers…”
Get full text
Journal Article -
7
The insect perspective on Z-disc structure and biology
Published in Journal of cell science (15-10-2022)“…ABSTRACT Myofibrils are the intracellular structures formed by actin and myosin filaments. They are paracrystalline contractile cables with unusually…”
Get full text
Journal Article -
8
Non-cell autonomous regulation of cell–cell signaling and differentiation by mitochondrial ROS
Published in The Journal of cell biology (02-12-2024)“…Mitochondrial reactive oxygen species (ROS) function intrinsically within cells to induce cell damage, regulate transcription, and cause genome instability…”
Get full text
Journal Article -
9
The transcription factors aryl hydrocarbon receptor and MYC cooperate in the regulation of cellular metabolism
Published in The Journal of biological chemistry (28-08-2020)“…The transcription factor AHR (aryl hydrocarbon receptor) drives the expression of genes involved in detoxification pathways in cells exposed to pollutants and…”
Get full text
Journal Article -
10
The AHR target gene scinderin activates the WNT pathway by facilitating the nuclear translocation of β-catenin
Published in Journal of cell science (15-10-2022)“…The ligand-activated transcription factor aryl hydrocarbon receptor (AHR) regulates cellular detoxification, proliferation and immune evasion in a range of…”
Get full text
Journal Article -
11
Increasing the field-of-view in oblique plane microscopy via optical tiling
Published in Biomedical optics express (01-11-2022)“…Fast volumetric imaging of large fluorescent samples with high-resolution is required for many biological applications. Oblique plane microscopy (OPM) provides…”
Get full text
Journal Article