Search Results - "Castro, Javier García"

Adipose Tissue‐Derived Mesenchymal Stem Cells Have In Vivo Immunosuppressive Properties Applicable for the Control of the Graft‐Versus‐Host Disease by Yañez, Rosa, Lamana, María Luisa, García‐Castro, Javier, Colmenero, Isabel, Ramírez, Manuel, Bueren, Juan A.

“…Previous studies have shown the relevance of bone marrow‐derived MSCs (BM‐MSCs) in controlling graft‐versus‐host disease (GVHD) after allogeneic…”
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Clonal dynamics in osteosarcoma defined by RGB marking by Gambera, Stefano, Abarrategi, Ander, González-Camacho, Fernando, Morales-Molina, Álvaro, Roma, Josep, Alfranca, Arantzazu, García-Castro, Javier

“…Osteosarcoma is a type of bone tumour characterized by considerable levels of phenotypic heterogeneity, aneuploidy, and a high mutational rate. The life…”
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Role of Activator Protein‐1 Complex on the Phenotype of Human Osteosarcomas Generated from Mesenchymal Stem Cells by Gambera, Stefano, Abarrategi, Ander, Rodríguez‐Milla, Miguel A., Mulero, Francisca, Menéndez, Sofía T., Rodriguez, René, Navarro, Samuel, García‐Castro, Javier

“…Osteosarcoma (OS) is a highly aggressive bone tumor that usually arises intramedullary at the extremities of long bones. Due to the fact that the peak of…”
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Combination immunotherapy using G-CSF and oncolytic virotherapy reduces tumor growth in osteosarcoma by Morales-Molina, Alvaro, Gambera, Stefano, Leo, Angela, García-Castro, Javier

“…BackgroundOsteosarcoma is the most common malignant solid tumor that affects bones, however, survival rates of patients with relapsed osteosarcoma have not…”
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Mesenchymal stem cells: biological properties and clinical applications by García-Gómez, Ignacio, Elvira, Gema, Zapata, Agustín G, Lamana, María L, Ramírez, Manuel, Castro, Javier García, Arranz, Mariano García, Vicente, Angeles, Bueren, Juan, García-Olmo, Damián

“…In the last decade, knowledge of mesenchymal stem cells (MSCs) has evolved rapidly; their immunomodulatory properties and paracrine interactions with specific…”
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The Phubbing Scale (PS-8) in the Portuguese population: psychometric properties by García-Castro, F. Javier, Abreu, Ana Maria, Rando, Belén, Blanca, María J.

“…Phubbing is defined as ignoring other individuals by using a mobile phone during a face-to-face conversation. The Phubbing Scale (PS) was developed to assess…”
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FUS‐CHOP Fusion Protein Expression Coupled to p53 Deficiency Induces Liposarcoma in Mouse but Not in Human Adipose‐Derived Mesenchymal Stem/Stromal Cells by Rodriguez, Rene, Rubio, Ruth, Gutierrez‐Aranda, Ivan, Melen, Gustavo J., Elosua, Carolina, García‐Castro, Javier, Menendez, Pablo

“…Human sarcomas have been modeled in mice by expression of specific fusion genes in mesenchymal stem cells (MSCs). However, sarcoma models based on human MSCs…”
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Systemic cellular viroimmunotherapy for canine high-grade gliomas by Cloquell, Ana, Mateo, Isidro, Gambera, Stefano, Pumarola, Martí, Alemany, Ramon, García-Castro, Javier, Perisé-Barrios, Ana Judith

“…BackgroundOncolytic viruses constitute a growing field of interest, both in human and veterinary oncology, given that they are particularly helpful for…”
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Safety and Efficacy of an Oncolytic Adenovirus as an Immunotherapy for Canine Cancer Patients by Martín-Carrasco, Clara, Delgado-Bonet, Pablo, Tomeo-Martín, Beatriz Davinia, Pastor, Josep, de la Riva, Claudia, Palau-Concejo, Paula, del Castillo, Noemí, García-Castro, Javier, Perisé-Barrios, Ana Judith

“…The use of oncolytic viruses is an innovative approach to lyse tumor cells and induce antitumor immune responses. Eight dogs diagnosed with…”
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Dopamine Mobilizes Mesenchymal Progenitor Cells Through D2‐Class Receptors and Their PI3K/AKT Pathway by Mirones, Isabel, Ángel Rodríguez‐Milla, Miguel, Cubillo, Isabel, Mariñas‐Pardo, Luis, de la Cueva, Teresa, Zapata, Agustín, González, Carlos, Ramírez, Manuel, García‐Castro, Javier

“…As the nervous system exerts direct and indirect effects on stem cells mobilization and catecholamines mobilize hematopoietic stem cells, we hypothesized that…”
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Biodistribution Analysis of Oncolytic Adenoviruses in Canine Patient Necropsy Samples Treated with Cellular Virotherapy by Gómez, Ana, Sardón, David, Cejalvo, Teresa, Vázquez, Fernando, García-Castro, Javier, Perisé-Barrios, Ana Judith

“…Oncolytic immunotherapy with competent viruses is an emerging approach in cancer treatment. The clinical safety of many types of oncolytic viruses (OVs) has…”
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First-in-Human, First-in-Child Trial of Autologous MSCs Carrying the Oncolytic Virus Icovir-5 in Patients with Advanced Tumors by Ruano, David, López-Martín, José A., Moreno, Lucas, Lassaletta, Álvaro, Bautista, Francisco, Andión, Maitane, Hernández, Carmen, González-Murillo, África, Melen, Gustavo, Alemany, Ramón, Madero, Luis, García-Castro, Javier, Ramírez, Manuel

“…We present here the results of a first-in-human, first-in-child trial for patients with relapsed/refractory solid tumors using Celyvir, an advanced therapy…”
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Dedifferentiated adult articular chondrocytes: a population of human multipotent primitive cells by de la Fuente, Ricardo, Abad, José Luis, Garcı́a-Castro, Javier, Fernández-Miguel, Gemma, Petriz, Jordi, Rubio, Daniel, Vicario-Abejón, Carlos, Guillén, Pedro, González, Manuel A, Bernad, Antonio

“…Objective. To test the hypothesis that dedifferentiated adult human cartilage chondrocytes (HAC) are a true multipotent primitive population. Methods. Studies…”
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Neural cue-reactivity in pathological gambling as evidence for behavioral addiction: a systematic review by García-Castro, Javier, Cancela, Ana, Cárdaba, Miguel A. M.

“…Increasing incidence of problem gambling has led to prioritizing the problem from the point of view of public health. Additionally, gambling disorder has been…”
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Prospects of Pluripotent and Adult Stem Cells for Rare Diseases by García-Castro, Javier, Singeç, Ilyas

“…Rare diseases are highly diverse and complex regarding molecular underpinning and clinical manifestation and afflict millions of patients worldwide. The lack…”
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Aldh1 Expression and Activity Increase During Tumor Evolution in Sarcoma Cancer Stem Cell Populations by Martinez-Cruzado, Lucia, Tornin, Juan, Santos, Laura, Rodriguez, Aida, García-Castro, Javier, Morís, Francisco, Rodriguez, Rene

“…Tumors evolve from initial tumorigenic events into increasingly aggressive behaviors in a process usually driven by subpopulations of cancer stem cells (CSCs)…”
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Enhanced Antitumor Efficacy of Oncolytic Adenovirus-loaded Menstrual Blood-derived Mesenchymal Stem Cells in Combination with Peripheral Blood Mononuclear Cells by Moreno, Rafael, Fajardo, Carlos Alberto, Farrera-Sal, Marti, Perisé-Barrios, Ana Judith, Morales-Molina, Alvaro, Al-Zaher, Ahmed Abdullah, García-Castro, Javier, Alemany, Ramon

“…Several studies have evaluated the efficacy of using human oncolytic adenovirus (OAdv)-loaded mesenchymal stem cells (MSC) for cancer treatment. For example,…”
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Influence of carrier cells on the clinical outcome of children with neuroblastoma treated with high dose of oncolytic adenovirus delivered in mesenchymal stem cells by Melen, Gustavo J, Franco-Luzón, Lidia, Ruano, David, González-Murillo, África, Alfranca, Arantzazu, Casco, Fernando, Lassaletta, Álvaro, Alonso, Mercedes, Madero, Luís, Alemany, Ramón, García-Castro, Javier, Ramírez, Manuel

“…Highlights • First-in-humans, first-in-children use of MSCs as carriers for oncolytic virotherapy. • This strategy allows administering very high amount of…”
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Antitumor virotherapy using syngeneic or allogeneic mesenchymal stem cell carriers induces systemic immune response and intratumoral leukocyte infiltration in mice by Morales-Molina, Álvaro, Gambera, Stefano, Cejalvo, Teresa, Moreno, Rafael, Rodríguez-Milla, Miguel Ángel, Perisé-Barrios, Ana Judith, García-Castro, Javier

“…Oncolytic virotherapy uses oncolytic viruses that selectively replicate in cancer cells. The use of cellular vehicles with migration ability to tumors has been…”
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Repeated measures ANOVA and adjusted F-tests when sphericity is violated: which procedure is best? by Blanca, María J., Arnau, Jaume, García-Castro, F. Javier, Alarcón, Rafael, Bono, Roser

“…One-way repeated measures ANOVA requires sphericity. Research indicates that violation of this assumption has an important impact on Type I error. Although…”
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