Search Results - "Castro, Inês"

ACBD5 and VAPB mediate membrane associations between peroxisomes and the ER by Costello, Joseph L, Castro, Inês G, Hacker, Christian, Schrader, Tina A, Metz, Jeremy, Zeuschner, Dagmar, Azadi, Afsoon S, Godinho, Luis F, Costina, Victor, Findeisen, Peter, Manner, Andreas, Islinger, Markus, Schrader, Michael

“…Peroxisomes (POs) and the endoplasmic reticulum (ER) cooperate in cellular lipid metabolism and form tight structural associations, which were first observed…”
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Predicting the targeting of tail-anchored proteins to subcellular compartments in mammalian cells by Costello, Joseph L, Castro, Inês G, Camões, Fátima, Schrader, Tina A, McNeall, Doug, Yang, Jing, Giannopoulou, Evdokia-Anastasia, Gomes, Sílvia, Pogenberg, Vivian, Bonekamp, Nina A, Ribeiro, Daniela, Wilmanns, Matthias, Jedd, Gregory, Islinger, Markus, Schrader, Michael

“…Tail-anchored (TA) proteins contain a single transmembrane domain (TMD) at the C-terminus that anchors them to the membranes of organelles where they mediate…”
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Peroxisomal ACBD4 interacts with VAPB and promotes ER-peroxisome associations by Costello, Joseph L., Castro, Inês G., Schrader, Tina A., Islinger, Markus, Schrader, Michael

“…Cooperation between cellular organelles such as mitochondria, peroxisomes and the ER is essential for a variety of important and diverse metabolic processes…”
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Identification of seipin-linked factors that act as determinants of a lipid droplet subpopulation by Eisenberg-Bord, Michal, Mari, Muriel, Weill, Uri, Rosenfeld-Gur, Eden, Moldavski, Ofer, Castro, Inês G, Soni, Krishnakant G, Harpaz, Nofar, Levine, Tim P, Futerman, Anthony H, Reggiori, Fulvio, Bankaitis, Vytas A, Schuldiner, Maya, Bohnert, Maria

“…Functional heterogeneity within the lipid droplet (LD) pool of a single cell has been observed, yet the underlying mechanisms remain enigmatic. Here, we report…”
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Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson’s disease by Tufi, Roberta, Gandhi, Sonia, de Castro, Inês P., Lehmann, Susann, Angelova, Plamena R., Dinsdale, David, Deas, Emma, Plun-Favreau, Hélène, Nicotera, Pierluigi, Abramov, Andrey Y., Willis, Anne E., Mallucci, Giovanna R., Loh, Samantha H. Y., Martins, L. Miguel

“…Mutations in PINK1 cause early-onset Parkinson’s disease (PD). Studies in Drosophila melanogaster have highlighted mitochondrial dysfunction on loss of Pink1…”
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Cvm1 is a component of multiple vacuolar contact sites required for sphingolipid homeostasis by Bisinski, Daniel D, Gomes Castro, Inês, Mari, Muriel, Walter, Stefan, Fröhlich, Florian, Schuldiner, Maya, González Montoro, Ayelén

“…Membrane contact sites are specialized platforms formed between most organelles that enable them to exchange metabolites and influence the dynamics of each…”
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Chitinase 3-like-1 and fibronectin in the cargo of extracellular vesicles shed by human macrophages influence pancreatic cancer cellular response to gemcitabine by Xavier, Cristina P.R., Castro, Inês, Caires, Hugo R., Ferreira, Dylan, Cavadas, Bruno, Pereira, Luisa, Santos, Lúcio L., Oliveira, Maria J., Vasconcelos, M. Helena

“…Tumour-associated macrophages have been implicated in pancreatic ductal adenocarcinoma (PDAC) therapy response and Extracellular vesicles (EVs) shed by…”
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High Serum Folate Concentration, Vitamin B12 Deficiency, and Anthropometric Nutritional Status in Brazilian Children Aged 6-59 Months: Data from the Brazilian National Survey of Child Nutrition by Salvatte, Keronlainy, Farias, Dayana Rodrigues, Normando, Paula, Berti, Talita Lelis, Castro, Inês Rugani Ribeiro de, Kac, Gilberto

“…Vitamin B12 and folate are key nutrients that help children reach their full potential in growth and development; however, little is known about the status of…”
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Mind the Organelle Gap – Peroxisome Contact Sites in Disease by Castro, Inês Gomes, Schuldiner, Maya, Zalckvar, Einat

“…The eukaryotic cell is organized as a complex grid system where membrane-bound cellular compartments, organelles, must be localized to the right place at the…”
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A role for Mitochondrial Rho GTPase 1 (MIRO1) in motility and membrane dynamics of peroxisomes by Castro, Inês G., Richards, David M., Metz, Jeremy, Costello, Joseph L., Passmore, Josiah B., Schrader, Tina A., Gouveia, Ana, Ribeiro, Daniela, Schrader, Michael

“…Peroxisomes are dynamic organelles which fulfil essential roles in lipid and ROS metabolism. Peroxisome movement and positioning allows interaction with other…”
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The strategic role of CSP to disseminate knowledge in the field of food and nutrition by Castro, Inês Rugani Ribeiro de, Kac, Gilberto

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Framing poor diet quality as malnutrition: the Brazilian National Survey on Child Nutrition (ENANI-2019) by Scrinis, Gyorgy, Castro, Inês Rugani Ribeiro de

“…Based on the Brazilian National Survey on Child Nutrition (ENANI-2019) results, this article reflects on the adequacy of the "malnutrition in all its forms"…”
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Reproducibility and Validity of Capillary Dried Blood Spot for Diagnosis of Vitamin A Deficiency and Anemia in Children <5 Years Old by da Silva Pereira, Alessandra, da Silva, Ana C F, Bezerra, Flávia F, Citelli, Marta, Nogueira Neto, José F, de Castro, Inês R R

“…Vitamin A deficiency (VAD) and anemia are the most prevalent nutritional deficiency in children globally. The dried blood spot (DBS) method has been used in…”
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Promethin Is a Conserved Seipin Partner Protein by Castro, Inês G, Eisenberg-Bord, Michal, Persiani, Elisa, Rochford, Justin J, Schuldiner, Maya, Bohnert, Maria

“…Seipin (BSCL2/SPG17) is a key factor in lipid droplet (LD) biology, and its dysfunction results in severe pathologies, including the fat storage disease…”
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Opposing p53 and mTOR/AKT promote an in vivo switch from apoptosis to senescence upon telomere shortening in zebrafish by El Maï, Mounir, Marzullo, Marta, de Castro, Inês Pimenta, Ferreira, Miguel Godinho

“…Progressive telomere shortening during lifespan is associated with restriction of cell proliferation, genome instability and aging. Apoptosis and senescence…”
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Synaesthetic landscapes: looking for the missing senses in an eighteenth-century palace in Mafra, Portugal by Casimiro, Tania, Santos, Joel, Castro, Inês

“…In 1781, a book discussing the relationship between cats and dogs was published in Lisbon. Among the illustrations, there is a representation of a palace, more…”
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Antibiotics from Haloarchaea: What Can We Learn from Comparative Genomics? by de Castro, Inês, Mendo, Sónia, Caetano, Tânia

“…The knowledge of antibiotics produced by Archaea (archaeocins) is still limited. So far, only two types of archaeocins are known: (i) sulfolobicins, produced…”
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Research on commercial milk formulas for young children: A scoping review by Cavalcanti, Maria Birman, Silva, Isabela da Costa Gaspar da, Lamarca, Fernando, Castro, Inês Rugani Ribeiro

“…A scoping review of publications about commercial milk formulas intended for or consumed by children 12–36 months (CMF 12–36) was conducted. This review aimed…”
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Altered frontoparietal connectivity in patients with obsessive-compulsive disorder during an fMRI cognitive reappraisal task by Picó-Pérez, Maria, Barbosa, Renato, Couto, Beatriz, Castro, Inês, Magalhães, Ricardo, Sousa, Nuno, Ferreira, Sónia, Morgado, Pedro

“…•OCD patients were less successful at lowering the emotional impact of negative images.•There were no significant between-group differences in brain…”
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Deleterious variants in TRAK1 disrupt mitochondrial movement and cause fatal encephalopathy by Barel, Ortal, Malicdan, May Christine V, Ben-Zeev, Bruria, Kandel, Judith, Pri-Chen, Hadass, Stephen, Joshi, Castro, Inês G, Metz, Jeremy, Atawa, Osama, Moshkovitz, Sharon, Ganelin, Esther, Barshack, Iris, Polak-Charcon, Sylvie, Nass, Dvora, Marek-Yagel, Dina, Amariglio, Ninette, Shalva, Nechama, Vilboux, Thierry, Ferreira, Carlos, Pode-Shakked, Ben, Heimer, Gali, Hoffmann, Chen, Yardeni, Tal, Nissenkorn, Andreea, Avivi, Camila, Eyal, Eran, Kol, Nitzan, Glick Saar, Efrat, Wallace, Douglas C, Gahl, William A, Rechavi, Gideon, Schrader, Michael, Eckmann, David M, Anikster, Yair

“…Cellular distribution and dynamics of mitochondria are regulated by several motor proteins and a microtubule network. In neurons, mitochondrial trafficking is…”
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