Search Results - "Castro, Brenda F. M."

AAV-Based Strategies for Treatment of Retinal and Choroidal Vascular Diseases: Advances in Age-Related Macular Degeneration and Diabetic Retinopathy Therapies by Castro, Brenda F. M., Steel, Jason C., Layton, Christopher J.

“…Age-related macular degeneration (AMD) and diabetic retinopathy (DR) are vascular diseases with high prevalence, ranking among the leading causes of blindness…”
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Nicorandil antiallodynic activity in a model of neuropathic pain is associated with the activation of ATP-dependent potassium channels and opioidergic pathways, and reduced production of cytokines and neutrophils recruitment in paw, sciatic nerve, and dorsal root ganglia by Braga, Alysson V, Morais, Marcela Í, Delfino, Darly G S, Costa, Sarah O A M, Barbosa, Bárbara C M, Rodrigues, Felipe F, Melo, Ivo S F, Matos, Rafael C, Castro, Brenda F M, Cunha Júnior, Armando S, Braga, Taniris C, de Fátima, Ângelo, Coelho, Márcio M, Machado, Renes R

“…Recently, we demonstrated that nicorandil inhibits mechanical allodynia induced by paclitaxel. In the present study, we evaluated the effect induced by…”
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Permeability and in vivo distribution of poly(Ɛ-caprolactone) nanoparticles loaded with zidovudine by Magalhães, Milena C. R. S., Castro, Brenda F. M., de Castro, Whocely V., Barros, Andre L. B., Fernandes, Renata S., Silva-Cunha, Armando, Fialho, Sílvia L.

“…Zidovudine (AZT) is one of first choice drugs for the treatment of acquired immunodeficiency syndrome (AIDS). Despite its efficacy to control virus…”
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RI75, a curcumin analogue, inhibits tumor necrosis factor-α and interleukin-6 production and exhibits antiallodynic and antiedematogenic activities in mice by Costa, Sarah O. A. M., Rodrigues, Ianny B., Braga, Alysson V., Barbosa, Bárbara C. M., Silva, Roger R. L., Rodrigues, Felipe F., Melo, Ivo S. F., Morais, Marcela Í., Castro, Brenda F. M., Júnior, Armando S. Cunha, Maltarollo, Vinícius G., Oliveira, Renata B., Coelho, Márcio M., Machado, Renes R.

“…Curcumin and its analogues exhibited anti-inflammatory activity in different experimental models. Recently, we synthesized (2 E ,3 E…”
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Antiangiogenic potential of small polypeptide sequences: In vivo assays, cytotoxicity, synthetic approaches and influence of C-terminal carboxyamidation by Cordeiro, Lídia P.B., de Carvalho, Izabella E., Castro, Brenda F.M., Dourado, Lays F.N., Guimarães, Carlos F.C.R., Lula, Ivana S., Fialho, Silvia L., Júnior, Armando da Silva Cunha, Resende, Jarbas M., Gomes, Elionai C. de L.

“…•The peptide PSAIWF-NH2 is comparable to bevacizumab in terms of activity.•The hexapeptide can be easily obtained by a simple solid-phase synthesis…”
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Safety and in vivo release of fluconazole-loaded implants in rabbits' eyes by Silva, Gisele R., Almeida, Ana Paula R., Fernandes-Cunha, Gabriella M., Castro, Brenda F.M., Vieira, Lorena C., Fulgêncio, Gustavo O., Silva-Cunha, Armando, Fialho, Sílvia L.

“…Drug delivery to the eye cavity remains a challenge, owing to the ocular-blood barriers and rapid clearance of the drugs from aqueous humor and choroid. In…”
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