Search Results - "Castro, Bernardo"
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Pathophysiology of Blood-Brain Barrier Permeability Throughout the Different Stages of Ischemic Stroke and Its Implication on Hemorrhagic Transformation and Recovery
Published in Frontiers in neurology (09-12-2020)“…The blood-brain barrier (BBB) is a dynamic interface responsible for maintaining the central nervous system homeostasis. Its unique characteristics allow…”
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Brazilian science under continuous attack
Published in The Lancet (British edition) (01-01-2022)Get full text
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Diagnostic accuracy of CT angiography and CT perfusion imaging for detecting distal medium vessel occlusions: Protocol for a systematic review and meta-analysis
Published in PloS one (10-04-2023)“…Distal medium vessel occlusions (DMVOs) represent 25-40% of all acute ischemic strokes (AIS). DMVO clinical syndromes are heterogenous, but as eloquent brain…”
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Novel Genetic Constructs for Production of Recombinant HTLV-1/2 Antigens and Evaluation of Their Reactivity to Plasma Samples from HTLV-1-Infected Patients
Published in Journal of clinical microbiology (19-03-2021)“…Human T-cell leukemia virus type 1 (HTLV-1) can cause life-threatening diseases for which there are no effective treatments. Prevention of HTLV-1 infection…”
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HTLV-1 is predominantly sexually transmitted in Salvador, the city with the highest HTLV-1 prevalence in Brazil
Published in PloS one (03-02-2017)“…Salvador is the city with the highest number of HTLV-1 infected individuals in Brazil, yet the main route of HTLV-1 transmission is unknown. To investigate the…”
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Higher education managers’ perspectives on quality management and technology acceptance: A tale of elders, mediators, and working bees in times of Covid-19
Published in Computers in human behavior (01-06-2022)“…The Covid-19 pandemic has emphasized the role of educational management information systems (EMIS) for quality management (QM) in higher education, and set new…”
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Molecular characterization of HTLV‐1 genomic region hbz from patients with different clinical conditions
Published in Journal of medical virology (01-11-2021)“…The human T‐cell lymphotropic virus type‐1 (HTLV‐1) is associated with severe pathologies, such as HTLV‐1‐associated myelopathy/tropical spastic paraparesis…”
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Human T Cell Lymphotropic Virus Type 1 Global Prevalence Associated with the Human Development Index: Systematic Review with Meta-Analysis
Published in AIDS research and human retroviruses (01-04-2023)“…In 2012, the number of people infected with human T cell lymphotropic virus type 1 (HTLV-1) was estimated to be 10 million worldwide. Prevalence varies…”
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Blocking HTLV-1/2 silent transmission in Brazil: Current public health policies and proposal for additional strategies
Published in PLoS neglected tropical diseases (01-09-2021)“…Human T-cell lymphotropic viruses 1 and 2 (HTLV-1/2) are relatively common in Brazil but remain silent and neglected infections. HTLV-1 is associated with a…”
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Functional capacity of natural killer cells in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients
Published in BMC infectious diseases (17-05-2019)“…Natural killer (NK) cells are part of the innate immune system and provide surveillance against viruses and cancers. The ability of NK cells to kill…”
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In vitro immunomodulatory effects of Caryocar villosum oil on murine macrophages
Published in Biomedicine & pharmacotherapy (01-10-2024)“…Macrophages undergo activation in response to multiple stimuli, including pathogens, growth factors and natural products. The inflammatory response and…”
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Imbalanced IL10/TGF-β production by regulatory T-lymphocytes in patients with HTLV-1-associated myelopathy/ tropical spastic paraparesis
Published in BMC infectious diseases (28-06-2024)“…Human T-cell lymphotropic virus type 1 (HTLV-1), also denominated Human T-cell leukemia virus-1, induces immune activation and secretion of proinflammatory…”
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Association between high proviral load, cognitive impairment, and white matter brain lesions in HTLV-1-infected individuals
Published in Journal of neurovirology (01-12-2021)“…The association between high proviral load (PVL) in peripheral blood mononuclear cells (PBMC), cognitive disturbance and white matter brain lesions in…”
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Epidemiological and molecular evidence of intrafamilial transmission through sexual and vertical routes in Bahia, the state with the highest prevalence of HTLV-1 in Brazil
Published in PLoS neglected tropical diseases (01-09-2023)“…Familial clustering of HTLV-1 and related diseases has been reported in Brazil. However, intrafamilial transmission of HTLV-1 based on molecular analysis has…”
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Performance of Commercially Available Serological Screening Tests for Human T-Cell Lymphotropic Virus Infection in Brazil
Published in Journal of clinical microbiology (01-12-2018)“…Serological screening for human T-cell lymphotropic virus type 1 (HTLV-1) is usually performed using enzyme-linked immunosorbent assay (ELISA), particle…”
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Prevalence and characteristics of HTLV-associated uveitis in patients from Bahia, an endemic area for HTLV − 1 in Brazil
Published in Virology journal (21-08-2023)“…HTLV-1-associated uveitis (HAU) is an inflammatory reaction of the choroid, retina, optic nerve and vitreous that can lead to vision impairment. The worldwide…”
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Line Immunoassay for Confirmation and Discrimination of Human T-Cell Lymphotropic Virus Infections in Inconclusive Western Blot Serum Samples from Brazil
Published in Journal of clinical microbiology (23-12-2019)“…Difficulties in confirming and discriminating human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2 infections by serological Western blot (WB) assays…”
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Distribution of Human T-Lymphotropic Virus (HTLV) and Hepatitis C Co-infection in Bahia, Brazil
Published in PloS one (21-07-2020)“…Both Human T-lymphotropic virus type 1 (HTLV-1) and hepatitis C virus (HCV) are endemic in Brazil. In Salvador, the capital of the state of Bahia, 2% and 1.5%…”
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HIV/Aids and COVID-19 in Brazil: in four decades, two antithetical approaches to face serious pandemics
Published in Memórias do Instituto Oswaldo Cruz (01-01-2021)“…In the space of four decades, Brazil has faced two serious pandemics: human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) and…”
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Permeability of the blood-brain barrier through the phases of ischaemic stroke and relation with clinical outcome: protocol for a systematic review
Published in BMJ open (18-09-2020)“…IntroductionIschaemic stroke is the most prevalent type of stroke and is characterised by a myriad of pathological events triggered by a vascular arterial…”
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