Search Results - "Castro, Alexandre Luz"

The progression of pulmonary arterial hypertension induced by monocrotaline is characterized by lung nitrosative and oxidative stress, and impaired pulmonary artery reactivity by Zimmer, Alexsandra, Teixeira, Rayane Brinck, Constantin, Rosalia Lempk, Campos-Carraro, Cristina, Aparicio Cordero, Elvira Alicia, Ortiz, Vanessa Duarte, Donatti, Luiza, Gonzalez, Esteban, Bahr, Alan Christhian, Visioli, Fernanda, Baldo, Guilherme, Luz de Castro, Alexandre, Araujo, Alex Sander, Belló-Klein, Adriane

“…The time-course of pulmonary arterial hypertension in the monocrotaline (MCT) model was investigated. Male rats were divided into two groups: MCT (received a…”
Get full text

Thyroid hormone treatment improved the response to maximum exercise test and preserved the ventricular geometry in myocardial infarcted rats by Teixeira, Rayane Brinck, Zimmer, Alexsandra, Godoy, Alessandra Eifler Guerra, Castro, Alexandre Luz, Campos‐Carraro, Cristina, Belló‐Klein, Adriane, da Rosa Araujo, Alex Sander

“…New Findings What is the central question of this study? Does thyroid hormone treatment given after myocardial infarction preserve left ventricular function…”
Get full text

Carvedilol and thyroid hormones co-administration mitigates oxidative stress and improves cardiac function after acute myocardial infarction by Ortiz, Vanessa Duarte, Türck, Patrick, Teixeira, Rayane, Lima-Seolin, Bruna Gazzi, Lacerda, Denise, Fraga, Schauana Freitas, Hickmann, Alexandre, Gatelli Fernandes, Tânia Regina, Belló-Klein, Adriane, Luz de Castro, Alexandre, da Rosa Araujo, Alex Sander

“…After acute myocardial infarction (AMI), reactive oxygen species and oxidative stress have important roles in the progression to heart failure. As a…”
Get full text

Impact of thyroid hormones and grape juice on biochemical markers and metabolic control proteins in experimental pulmonary arterial hypertension by Proença, Isabel Cristina Teixeira, Türck, Patrick, Ortiz, Vanessa Duarte, Carraro, Cristina Campos, Belló-Klein, Adriane, Castro, Alexandre Luz de, Dani, Caroline, Araujo, Alex Sander da Rosa

“…Background-Pulmonary arterial hypertension (PAH) increases afterload in the right ventricle (RV), inducing adverse ventricular remodelling. Objective- This…”
Get full text

Effects of sleep restriction during pregnancy on the mother and fetuses in rats by Pardo, Grace Violeta Espinoza, Goularte, Jéferson Ferraz, Hoefel, Ana Lúcia, de Castro, Alexandre Luz, Kucharski, Luiz Carlos, da Rosa Araujo, Alex Sander, Lucion, Aldo Bolten

“…Abstract The present study aimed to analyze the effects of sleep restriction (SR) during pregnancy in rats. The following three groups were studied: home cage…”
Get full text

Cardioprotective effects of thyroid hormones in a rat model of myocardial infarction are associated with oxidative stress reduction by de Castro, Alexandre Luz, Tavares, Angela Vicente, Campos, Cristina, Fernandes, Rafael Oliveira, Siqueira, Rafaela, Conzatti, Adriana, Bicca, Amanda M., Fernandes, Tânia Regina G., Sartório, Carmem L., Schenkel, Paulo Cavalheiro, Belló-Klein, Adriane, da Rosa Araujo, Alex Sander

“…•This study evaluated thyroid hormones effects in oxidative stress after infarction.•T3 and T4 administration reduced ROS levels induced by myocardial…”
Get full text

Melatonin effects on oxidative stress and on TLR4/NF-kβ inflammatory pathway in the right ventricle of rats with pulmonary arterial hypertension by Lisboa, Cristiane Dias, Maciel de Souza, José Luciano, Gaspar, Custódio José, Turck, Patrick, Ortiz, Vanessa Duarte, Teixeira Proença, Isabel Cristina, Fernandes, Tânia Regina G., Fernandes, Elissa, Tasca, Silvio, Carraro, Cristina Campos, Belló-Klein, Adriane, Sander da Rosa Araujo, Alex, Luz de Castro, Alexandre

“…Pulmonary arterial hypertension (PAH) is characterised by an increase in mean pulmonary arterial pressure and a compromised the right ventricle (RV), together…”
Get full text

Sulforaphane Effects on Cardiac Function and Calcium-Handling–Related Proteins in 2 Experimental Models of Heart Disease: Ischemia-Reperfusion and Infarction by Poletto Bonetto, Jéssica Hellen, Luz de Castro, Alexandre, Fernandes, Rafael Oliveira, Corssac, Giana Blume, Cordero, Elvira Aparicio, Schenkel, Paulo Cavalheiro, Sander da Rosa Araujo, Alex, Belló-Klein, Adriane

“…Sulforaphane (SFN) is a natural exogenous antioxidant from cruciferous vegetables already shown to improve cardiac function in cardiovascular diseases. The aim…”
Get full text

Influence of carvedilol and thyroid hormones on inflammatory proteins and cardioprotective factor HIF-1α in the infarcted heart by Ortiz, Vanessa Duarte, Teixeira, Rayane Brinck, Türck, Patrick, Corssac, Giana Blume, Belló-Klein, Adriane, de Castro, Alexandre Luz, Araujo, Alex Sander da Rosa

“…Inflammatory pathways of Toll-like receptor 4 (TLR4) and NLRP3 inflammasome contribute to acute myocardial infarction (AMI) pathophysiology. The…”
Get more information

Effect of free and nanoencapsulated copaiba oil on monocrotaline-induced pulmonary arterial hypertension by Campos, Cristina, Luz de Castro, Alexandre, Vicente Tavares, Angela Maria, Fernandes, Rafael Oliveira, Ortiz, Vanessa Duarte, Barboza, Tatiane Evelyn, Pereira, Cláudio, Apel, Miriam, Santos da Silva, Onilda, Llesuy, Susana, Sander da Rosa Araujo, Alex, Belló-Klein, Adriane

“…ABSTRACTCopaiba oil comes from an Amazonian tree and has been used as an alternative medicine in Brazil. However, it has not been investigated yet in the…”
Get full text

Decreased PGC1-α levels and increased apoptotic protein signaling are associated with the maladaptive cardiac hypertrophy in hyperthyroidism by Teixeira, Rayane Brinck, Barboza, Tatiane Evelyn, de Araújo, Carla Cristina, Siqueira, Rafaela, de Castro, Alexandre Luz, Bonetto, Jéssica Hellen Poletto, de Lima-Seolin, Bruna Gazzi, Carraro, Cristina Campos, Belló-Klein, Adriane, Singal, Pawan K, da Rosa Araujo, Alex Sander

“…Hyperthyroidism can lead to the activation of proteins which are associated with inflammation, apoptosis, hypertrophy, and heart failure. This study aimed to…”
Get full text

Neonatal hyperglycemia induces cell death in the rat brain by Rosa, Andrea Pereira, Mescka, Caroline Paula, Catarino, Felipe Maciel, de Castro, Alexandre Luz, Teixeira, Rayane Brinck, Campos, Cristina, Baldo, Guilherme, Graf, Débora Dalmas, de Mattos-Dutra, Angela, Dutra-Filho, Carlos Severo, da Rosa Araujo, Alex Sander

“…Several studies have examined neonatal diabetes, a rare disease characterized by hyperglycemia and low insulin levels that is usually diagnosed in the first…”
Get full text

The brief methylprednisolone administration is crucial to mitigate cardiac dysfunction after myocardial infarction by Bahr, Alan Christhian, Luz, Julia Paim DA, Teixeira, Rayane Brinck, Türck, Patrick, Zimmer, Alexsandra, Castro, Alexandre Luz DE, Reis, Eduardo Echer Dos, Visioli, Fernanda, Belló-Klein, Adriane, Araujo, Alex Sander DA Rosa, Schenkel, Paulo Cavalheiro

“…Acute myocardial infarction (AMI) is one of the major causes of heart failure and mortality. Glucocorticoids administration post-infarction has long been…”
Get full text

Effect of free and nanoemulsified β-caryophyllene on monocrotaline-induced pulmonary arterial hypertension by Carraro, Cristina Campos, Turck, Patrick, Bahr, Alan, Donatti, Luiza, Corssac, Giana, Lacerda, Denise, da Rosa Araujo, Alex Sander, de Castro, Alexandre Luz, Koester, Letícia, Belló-Klein, Adriane

“…Pulmonary arterial hypertension (PAH) is characterized by increased pulmonary vascular resistance (PVR), right ventricular (RV) failure and premature death…”
Get full text

Melatonin improves nitric oxide bioavailability in isoproterenol induced myocardial injury by Santos, Ramison, Turck, Patrick, de Mello Palma, Victor, Visioli, Fernanda, Ortiz, Vanessa Duarte, Proença, Isabel Cristina Teixeira, Fernandes, Tânia Regina G., Fernandes, Elissa, Tasca, Silvio, Carraro, Cristina Campos, Belló-Klein, Adriane, da Rosa Araujo, Alex Sander, Khaper, Neelam, de Castro, Alexandre Luz

“…Isoproterenol administration is associated with cardiac inflammation and decreased NO availability. Melatonin has been reported to have cardioprotective…”
Get full text

Effects of Pterostilbene on Heart and Lung Oxidative Stress Parameters in 2 Experimental Models of Cardiovascular Disease: Myocardial Infarction and Pulmonary Arterial Hypertension by de Castro, Alexandre Luz, Duarte Ortiz, Vanessa, Hickmann, Alexandre R., Santos Lacerda, Denise, Türck, Patrick, Campos Carraro, Cristina, Freitas, Schauana, Bello Klein, Adriane, Bassani, Valquiria, da Rosa Araujo, Alex Sander

“…Myocardial infarction (MI) and pulmonary arterial hypertension (PAH) are 2 prevalent cardiovascular diseases. In both conditions, oxidative stress is…”
Get full text

Effects of Carvedilol and Thyroid Hormones Co-administration on Apoptotic and Survival Proteins in the Heart After Acute Myocardial Infarction by Ortiz, Vanessa Duarte, Türck, Patrick, Teixeira, Rayane, Belló-Klein, Adriane, de Castro, Alexandre Luz, Araujo, Alex Sander da Rosa

“…Cellular death and survival signaling plays a key role in the progress of adverse cardiac remodeling after acute myocardial infarction (AMI). Therapeutic…”
Get full text

Cardioprotective doses of thyroid hormones improve NO bioavailability in erythrocytes and increase HIF-1α expression in the heart of infarcted rats by de Castro, Alexandre Luz, Fernandes, Rafael Oliveira, Ortiz, Vanessa D., Campos, Cristina, Bonetto, Jéssica H. P., Fernandes, Tânia Regina G., Conzatti, Adriana, Siqueira, Rafaela, Tavares, Angela Vicente, Belló-Klein, Adriane, Araujo, Alex Sander da Rosa

“…Infarction leads to a decrease in NO bioavailability in the erythrocytes. Thyroid hormones (TH) present positive effects after infarction. However, there are…”
Get full text

Thyroid hormones decrease the proinflammatory TLR4/NF-κβ pathway and improve functional parameters of the left ventricle of infarcted rats by de Castro, Alexandre Luz, Fernandes, Rafael Oliveira, Ortiz, Vanessa D., Campos, Cristina, Bonetto, Jéssica H.P., Fernandes, Tânia Regina G., Conzatti, Adriana, Siqueira, Rafaela, Tavares, Angela Vicente, Belló-Klein, Adriane, da Rosa Araujo, Alex Sander

“…Myocardial infarction leads to oxidative stress and promotes activation of the TLR4/NF-κβ proinflammatory pathway. Thyroid hormones (TH) are known to be…”
Get full text

Sulforaphane effects on postinfarction cardiac remodeling in rats: modulation of redox-sensitive prosurvival and proapoptotic proteins by Fernandes, Rafael Oliveira, De Castro, Alexandre Luz, Bonetto, Jéssica Hellen Poletto, Ortiz, Vanessa Duarte, Müller, Dalvana Daneliza, Campos-Carraro, Cristina, Barbosa, Silvia, Neves, Laura Tartari, Xavier, Léder Leal, Schenkel, Paulo Cavalheiro, Singal, Pawan, Khaper, Neelam, da Rosa Araujo, Alex Sander, Belló-Klein, Adriane

“…This study investigated whether sulforaphane (SFN), a compound found in cruciferous vegetables, could attenuate the progression of post-myocardial infarction…”
Get full text