Search Results - "Castrisos, J. C"

Inhibition of human leukocyte elastase by derivatives of N-hydroxysuccinimide. A structure-activity-relationship study by Groutas, W. C, Brubaker, M. J, Stanga, M. A, Castrisos, J. C, Crowley, J. P, Schatz, E. J

“…A series of compounds derived from 3-alkyl-N-hydroxysuccinimide have been synthesized and their inhibitory activity toward human leukocyte elastase has been…”
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The Lossen rearrangement in biological systems. Inactivation of leukocyte elastase and alpha-chymotrypsin by (dl)-3-benzyl-N-(methanesulfonyloxy) succinimide by Groutas, W C, Giri, P K, Crowley, J P, Castrisos, J C, Brubaker, M J

“…(dl)-3-Benzyl-N-(methanesulfonyloxy) succinimide 5 has been found to inactivate human leukocyte elastase and alpha-chymotrypsin efficiently and irreversibly…”
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Ionic inhibitors of human leukocyte elastase: pyridinium and phenyl carboxylate derivatives of 3-alkyl-N-hydroxysuccinimide by Groutas, W C, Stanga, M A, Castrisos, J C, Schatz, E J, Brubaker, M J

“…A series of pyridinium and phenyl carboxylate derivatives of 3-alkyl-N-hydroxysuccinimide has been synthesized; the compounds have been shown to be highly…”
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Hydantoin derivatives. A new class of inhibitors of human leukocyte elastase by Groutas, W C, Stanga, M A, Castrisos, J C, Schatz, E J

“…Derivatives of hydantoin have been found to inactivate human leukocyte elastase irreversibly. Chymotrypsin and cathepsin G are also inhibited by these…”
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Inactivation of leukocyte elastase by aryl azolides and sulfonate salts. Structure-activity relationship studies by Groutas, W. C, Brubaker, M. J, Zandler, M. E, Mazo-Gray, V, Rude, S. A, Crowley, J. P, Castrisos, J. C, Dunshee, D. A, Giri, P. K

“…The inhibitory activity of a series of aryl azolides and sulfonate salts toward human leukocyte elastase is reported. Several of the compounds were found to be…”
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Sulfonate salts of amino acids: novel inhibitors of the serine proteinases by Groutas, W C, Brubaker, M J, Zandler, M E, Stanga, M A, Huang, T L, Castrisos, J C, Crowley, J P

“…A series of amino acid-derived sulfonate salts have been synthesized. They were found to inactivate efficiently and selectively human leukocyte elastase. The…”
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