Search Results - "Castrignanò, Tiziana"

REDIportal: millions of novel A-to-I RNA editing events from thousands of RNAseq experiments by Mansi, Luigi, Tangaro, Marco Antonio, Lo Giudice, Claudio, Flati, Tiziano, Kopel, Eli, Schaffer, Amos Avraham, Castrignanò, Tiziana, Chillemi, Giovanni, Pesole, Graziano, Picardi, Ernesto

“…Abstract RNA editing is a relevant epitranscriptome phenomenon able to increase the transcriptome and proteome diversity of eukaryotic organisms. ADAR mediated…”
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HPC-T-Annotator: an HPC tool for de novo transcriptome assembly annotation by Arcioni, Lorenzo, Arcieri, Manuel, Martino, Jessica Di, Liberati, Franco, Bottoni, Paolo, Castrignanò, Tiziana

“…The availability of transcriptomic data for species without a reference genome enables the construction of de novo transcriptome assemblies as alternative…”
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MD-Ligand-Receptor: A High-Performance Computing Tool for Characterizing Ligand-Receptor Binding Interactions in Molecular Dynamics Trajectories by Pieroni, Michele, Madeddu, Francesco, Di Martino, Jessica, Arcieri, Manuel, Parisi, Valerio, Bottoni, Paolo, Castrignanò, Tiziana

“…Molecular dynamics simulation is a widely employed computational technique for studying the dynamic behavior of molecular systems over time. By simulating…”
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Genome-wide mapping of 8-oxo-7,8-dihydro-2′-deoxyguanosine reveals accumulation of oxidatively-generated damage at DNA replication origins within transcribed long genes of mammalian cells by Amente, Stefano, Di Palo, Giacomo, Scala, Giovanni, Castrignanò, Tiziana, Gorini, Francesca, Cocozza, Sergio, Moresano, Angela, Pucci, Piero, Ma, Bin, Stepanov, Irina, Lania, Luigi, Pelicci, Pier Giuseppe, Dellino, Gaetano Ivan, Majello, Barbara

“…Abstract 8-Oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) is one of the major DNA modifications and a potent pre-mutagenic lesion prone to mispair with…”
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HPC-REDItools: a novel HPC-aware tool for improved large scale RNA-editing analysis by Flati, Tiziano, Gioiosa, Silvia, Spallanzani, Nicola, Tagliaferri, Ilario, Diroma, Maria Angela, Pesole, Graziano, Chillemi, Giovanni, Picardi, Ernesto, Castrignanò, Tiziana

“…RNA editing is a widespread co-/post-transcriptional mechanism that alters primary RNA sequences through the modification of specific nucleotides and it can…”
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Molecular Docking and Dynamics Simulation Revealed the Potential Inhibitory Activity of New Drugs against Human Topoisomerase I Receptor by Madeddu, Francesco, Di Martino, Jessica, Pieroni, Michele, Del Buono, Davide, Bottoni, Paolo, Botta, Lorenzo, Castrignanò, Tiziana, Saladino, Raffaele

“…Human Topoisomerase I (hTop1p) is a ubiquitous enzyme that relaxes supercoiled DNA through a conserved mechanism involving transient breakage, rotation, and…”
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Lignin Nanoparticles Deliver Novel Thymine Biomimetic Photo-Adducts with Antimelanoma Activity by Gabellone, Sofia, Piccinino, Davide, Filippi, Silvia, Castrignanò, Tiziana, Zippilli, Claudio, Del Buono, Davide, Saladino, Raffaele

“…We report here the synthesis of novel thymine biomimetic photo-adducts bearing an alkane spacer between nucleobases and characterized by antimelanoma activity…”
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Molecular Dynamics Investigations of Human DNA-Topoisomerase I Interacting with Novel Dewar Valence Photo-Adducts: Insights into Inhibitory Activity by Di Martino, Jessica, Arcieri, Manuel, Madeddu, Francesco, Pieroni, Michele, Carotenuto, Giovanni, Bottoni, Paolo, Botta, Lorenzo, Castrignanò, Tiziana, Gabellone, Sofia, Saladino, Raffaele

“…Chronic exposure to ultraviolet (UV) radiation is known to induce the formation of DNA photo-adducts, including cyclobutane pyrimidine dimers (CPDs) and Dewar…”
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In Silico Predicting the Presence of the S100B Motif in Edible Plants and Detecting Its Immunoreactive Materials: Perspectives for Functional Foods, Dietary Supplements and Phytotherapies by Romano Spica, Vincenzo, Volpini, Veronica, Valeriani, Federica, Carotenuto, Giovanni, Arcieri, Manuel, Platania, Serena, Castrignanò, Tiziana, Clementi, Maria Elisabetta, Michetti, Fabrizio

“…The protein S100B is a part of the S100 protein family, which consists of at least 25 calcium-binding proteins. S100B is highly conserved across different…”
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One‐Pot Synthesis of ( S )‐Flavanones by a Double‐Face Promiscuous Chemo‐Enzymatic Cascade of Lipases by Ubertini, Valentina, Capecchi, Eliana, Tomaino, Elisabetta, Piccinino, Davide, Marchi, Elisa De, Bizzarri, Bruno Mattia, Carotenuto, Giovanni, Castrignanò, Tiziana, Saladino, Raffaele

“…Abstract The one‐pot stereoselective synthesis of ( S )‐flavanones from 2′‐hydroxyacetophenone and substituted aromatic aldehydes was obtained by a double‐face…”
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CoVaCS: a consensus variant calling system by Chiara, Matteo, Gioiosa, Silvia, Chillemi, Giovanni, D'Antonio, Mattia, Flati, Tiziano, Picardi, Ernesto, Zambelli, Federico, Horner, David Stephen, Pesole, Graziano, Castrignanò, Tiziana

“…The advent and ongoing development of next generation sequencing technologies (NGS) has led to a rapid increase in the rate of human genome re-sequencing data,…”
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Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas by Botti, Elisabetta, Spallone, Giulia, Moretti, Francesca, Marinari, Barbara, Pinetti, Valentina, Galanti, Sergio, De Meo, Paolo D'Onorio, De Nicola, Francesca, Ganci, Federica, Castrignanò, Tiziana, Pesole, Graziano, Chimenti, Sergio, Guerrini, Luisa, Fanciulli, Maurizio, Blandino, Giovanni, Karin, Michael, Costanzo, Antonio

“…The transcription factor interferon regulatory factor 6 (IRF6) regulates craniofacial development and epidermal proliferation. We recently showed that IRF6 is…”
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PMDB Protein Model Database by Castrignanò, Tiziana, De Meo, Paolo D'Onorio, Cozzetto, Domenico, Talamo, Ivano Giuseppe, Tramontano, Anna

“…The Protein Model Database (PMDB) is a public resource aimed at storing manually built 3D models of proteins. The database is designed to provide access to…”
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Brain de novo transcriptome assembly of a toad species showing polymorphic anti-predatory behavior by Chiocchio, Andrea, Libro, Pietro, Martino, Giuseppe, Bisconti, Roberta, Castrignanò, Tiziana, Canestrelli, Daniele

“…Understanding the genomic underpinnings of antipredatory behaviors is a hot topic in eco-evolutionary research. Yellow-bellied toad of the genus Bombina are…”
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A gene expression atlas for different kinds of stress in the mouse brain by Flati, Tiziano, Gioiosa, Silvia, Chillemi, Giovanni, Mele, Andrea, Oliverio, Alberto, Mannironi, Cecilia, Rinaldi, Arianna, Castrignanò, Tiziana

“…Stressful experiences are part of everyday life and animals have evolved physiological and behavioral responses aimed at coping with stress and maintaining…”
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De novo transcriptome assembly of an Antarctic nematode for the study of thermal adaptation in marine parasites by Palomba, Marialetizia, Libro, Pietro, Di Martino, Jessica, Roca-Geronès, Xavier, Macali, Armando, Castrignanò, Tiziana, Canestrelli, Daniele, Mattiucci, Simonetta

“…Understanding the genomic underpinnings of thermal adaptation is a hot topic in eco-evolutionary studies of parasites. Marine heteroxenous parasites have…”
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Integrated de novo transcriptome of Culex pipiens mosquito larvae as a resource for genetic control strategies by Mastrantonio, Valentina, Libro, Pietro, Di Martino, Jessica, Matera, Michele, Bellini, Romeo, Castrignanò, Tiziana, Urbanelli, Sandra, Porretta, Daniele

“…We present a de novo transcriptome of the mosquito vector Culex pipiens , assembled by sequences of susceptible and insecticide resistant larvae. The high…”
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ELIXIR-IT HPC@CINECA: high performance computing resources for the bioinformatics community by Castrignanò, Tiziana, Gioiosa, Silvia, Flati, Tiziano, Cestari, Mirko, Picardi, Ernesto, Chiara, Matteo, Fratelli, Maddalena, Amente, Stefano, Cirilli, Marco, Tangaro, Marco Antonio, Chillemi, Giovanni, Pesole, Graziano, Zambelli, Federico

“…The advent of Next Generation Sequencing (NGS) technologies and the concomitant reduction in sequencing costs allows unprecedented high throughput profiling of…”
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De novo transcriptome assembly and annotation for gene discovery in Salamandra salamandra at the larval stage by Libro, Pietro, Chiocchio, Andrea, De Rysky, Erika, Di Martino, Jessica, Bisconti, Roberta, Castrignanò, Tiziana, Canestrelli, Daniele

“…Dispersal is a key process in ecology and evolutionary biology, as it shapes biodiversity patterns over space and time. Attitude to disperse is unevenly…”
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Proteomic characterization of extracellular vesicles released by third stage larvae of the zoonotic parasite Anisakis pegreffii (Nematoda: Anisakidae) by Palomba, Marialetizia, Rughetti, Aurelia, Mignogna, Giuseppina, Castrignanò, Tiziana, Rahimi, Hassan, Masuelli, Laura, Napoletano, Chiara, Pinna, Valentina, Giorgi, Alessandra, Santoro, Mario, Schininà, Maria Eugenia, Maras, Bruno, Mattiucci, Simonetta

“…is a sibling species within the (s.l.) complex requiring marine homeothermic (mainly cetaceans) and heterothermic (crustaceans, fish, and cephalopods)…”
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