Search Results - "Castorena, Carlos"

The atypical antipsychotic olanzapine causes weight gain by targeting serotonin receptor 2C by Lord, Caleb C, Wyler, Steven C, Wan, Rong, Castorena, Carlos M, Ahmed, Newaz, Mathew, Dias, Lee, Syann, Liu, Chen, Elmquist, Joel K

“…Atypical antipsychotics such as olanzapine often induce excessive weight gain and type 2 diabetes. However, the mechanisms underlying these drug-induced…”
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Hypothalamic POMC neurons promote cannabinoid-induced feeding by Koch, Marco, Varela, Luis, Kim, Jae Geun, Kim, Jung Dae, Hernández-Nuño, Francisco, Simonds, Stephanie E., Castorena, Carlos M., Vianna, Claudia R., Elmquist, Joel K., Morozov, Yury M., Rakic, Pasko, Bechmann, Ingo, Cowley, Michael A., Szigeti-Buck, Klara, Dietrich, Marcelo O., Gao, Xiao-Bing, Diano, Sabrina, Horvath, Tamas L.

“…Hypothalamic pro-opiomelanocortin (POMC) neurons promote satiety. Cannabinoid receptor 1 (CB 1 R) is critical for the central regulation of food intake. Here…”
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Greater insulin sensitivity in calorie restricted rats occurs with unaltered circulating levels of several important myokines and cytokines by Sharma, Naveen, Castorena, Carlos M, Cartee, Gregory D

“…Calorie restriction (CR; ~60% of ad libitum, AL intake) has been associated with substantial alterations in body composition and insulin sensitivity. Recently,…”
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Tissue-specific responses of IGF-1/insulin and mTOR signaling in calorie restricted rats by Sharma, Naveen, Castorena, Carlos M, Cartee, Gregory D

“…Moderate calorie restriction (CR) (∼60% of ad libitum, AL, intake) has been associated with numerous favorable physiological outcomes in many species, and the…”
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Postexercise Improvement in Insulin-Stimulated Glucose Uptake Occurs Concomitant With Greater AS160 Phosphorylation in Muscle From Normal and Insulin-Resistant Rats by CASTORENA, Carlos M, ARIAS, Edward B, SHARMA, Naveen, CARTEE, Gregory D

“…Earlier research on rats with normal insulin sensitivity demonstrated that acute exercise increased insulin-stimulated glucose uptake (GU) concomitant with…”
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Weight loss by calorie restriction does not alter appetite‐regulating gut hormone responses from perfused rat small intestine by Gerstenberg, Marina K., Andersen, Daniel B., Torz, Lola, Castorena, Carlos M., Bookout, Angie L., Hartmann, Bolette, Rehfeld, Jens F., Petersen, Natalia, Holst, Jens J., Kuhre, Rune E.

“…Aim Postprandial secretion of the appetite‐inhibiting hormones, glucagon‐like peptide‐1 (GLP‐1), and peptide YY are reduced with obesity. It is unclear if the…”
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POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels by Caron, Alexandre, Dungan Lemko, Heather M, Castorena, Carlos M, Fujikawa, Teppei, Lee, Syann, Lord, Caleb C, Ahmed, Newaz, Lee, Charlotte E, Holland, William L, Liu, Chen, Elmquist, Joel K

“…Leptin is critical for energy balance, glucose homeostasis, and for metabolic and neuroendocrine adaptations to starvation. A prevalent model predicts that…”
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Cannabinoid receptor 1 signaling in hepatocytes and stellate cells does not contribute to NAFLD by Wang, Simeng, Zhu, Qingzhang, Liang, Guosheng, Franks, Tania, Boucher, Magalie, Bence, Kendra K, Lu, Mingjian, Castorena, Carlos M, Zhao, Shangang, Elmquist, Joel K, Scherer, Philipp E, Horton, Jay D

“…The endocannabinoid system regulates appetite and energy expenditure and inhibitors of cannabinoid receptor 1 (CB-1) induce weight loss with improvement in…”
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Cellular and synaptic reorganization of arcuate NPY/AgRP and POMC neurons after exercise by He, Zhenyan, Gao, Yong, Alhadeff, Amber L., Castorena, Carlos M., Huang, Yiru, Lieu, Linh, Afrin, Sadia, Sun, Jia, Betley, J. Nicholas, Guo, Hongbo, Williams, Kevin W.

“…Hypothalamic Pro-opiomelanocortin (POMC) and Neuropeptide Y/Agouti-Related Peptide (NPY/AgRP) neurons are critical nodes of a circuit within the brain that…”
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High-Phosphate Diet Induces Exercise Intolerance and Impairs Fatty Acid Metabolism in Mice by Peri-Okonny, Poghni, Baskin, Kedryn K, Iwamoto, Gary, Mitchell, Jere H, Smith, Scott A, Kim, Han Kyul, Szweda, Luke I, Bassel-Duby, Rhonda, Fujikawa, Teppei, Castorena, Carlos M, Richardson, James, Shelton, John M, Ayers, Colby, Berry, Jarett D, Malladi, Venkat S, Hu, Ming-Chang, Moe, Orson W, Scherer, Philipp E, Vongpatanasin, Wanpen

“…BACKGROUND:Inorganic phosphate (Pi) is used extensively as a preservative and a flavor enhancer in the Western diet. Physical inactivity, a common feature of…”
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Response to Kunos et al. and Lotersztajn and Mallat by Wang, Simeng, Zhu, Qingzhang, Liang, Guosheng, Franks, Tania, Boucher, Magalie, Bence, Kendra K, Lu, Mingjian, Castorena, Carlos M, Zhao, Shangang, Elmquist, Joel K, Scherer, Philipp E, Horton, Jay D

“…Wang et al response to Kunos et al who raise several issues that they can further clarify. They acknowledge that we could not use the TD97070 diet, which…”
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240-LB: Adipogenesis in Weight Regain Does Not Accelerate Adiposity in Mice by GERSTENBERG, MARINA K., BOOKOUT, ANGIE, CASTORENA, CARLOS M., TORZ, LOLA, DOVMARK, TOBIAS H., LUNDH, SOFIA, MADSEN, SUZI H., ANDERSEN, BIRGITTE S., PEDERSEN, THOMAS A., KUHRE, RUNE E., PETERSEN, NATALIA

“…Weight loss and regain are associated with profound cytoskeleton changes in collapsing and re-expanding adipocytes. These drastic changes in the adipose tissue…”
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Adipocyte Gs but not Gi signaling regulates whole-body glucose homeostasis by Caron, Alexandre, Reynolds, Ryan P., Castorena, Carlos M., Michael, Natalie J., Lee, Charlotte E., Lee, Syann, Berdeaux, Rebecca, Scherer, Philipp E., Elmquist, Joel K.

“…The sympathetic nervous system (SNS) is a key regulator of the metabolic and endocrine functions of adipose tissue. Increased SNS outflow promotes fat…”
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Mechanisms for independent and combined effects of calorie restriction and acute exercise on insulin-stimulated glucose uptake by skeletal muscle of old rats by Sharma, Naveen, Wang, Haiyan, Arias, Edward B, Castorena, Carlos M, Cartee, Gregory D

“…Either calorie restriction [CR; consuming 60-65% of ad libitum (AL) intake] or acute exercise can independently improve insulin sensitivity in old age, but…”
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Data Sampling Methods to Deal With the Big Data Multi-Class Imbalance Problem by Rendón, Eréndira, Alejo, Roberto, Castorena, Carlos, Isidro-Ortega, Frank J., Granda-Gutiérrez, Everardo E.

“…The class imbalance problem has been a hot topic in the machine learning community in recent years. Nowadays, in the time of big data and deep learning, this…”
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Fiber type effects on contraction-stimulated glucose uptake and GLUT4 abundance in single fibers from rat skeletal muscle by Castorena, Carlos M, Arias, Edward B, Sharma, Naveen, Bogan, Jonathan S, Cartee, Gregory D

“…To fully understand skeletal muscle at the cellular level, it is essential to evaluate single muscle fibers. Accordingly, the major goals of this study were to…”
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Ghrelin mediates exercise endurance and the feeding response post-exercise by Mani, Bharath K., Castorena, Carlos M., Osborne-Lawrence, Sherri, Vijayaraghavan, Prasanna, Metzger, Nathan P., Elmquist, Joel K., Zigman, Jeffrey M.

“…Exercise training has several well-established health benefits, including many related to body weight, appetite control, and blood glucose homeostasis…”
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Combined Loss of Ghrelin Receptor and Cannabinoid CB1 Receptor in Mice Decreases Survival but does not Additively Reduce Body Weight or Eating by Mani, Bharath K., Castorena, Carlos M., Vianna, Claudia R., Lee, Charlotte E., Metzger, Nathan P., Vijayaraghavan, Prasanna, Osborne-Lawrence, Sherri, Elmquist, Joel K., Zigman, Jeffrey M.

“…•Genetic deletion of GHSR does not exaggerate the reduced body weight, fat mass, or lean mass exhibited by mice lacking CB1R.•Genetic deletion of both GHSR and…”
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Heterogeneous effects of calorie restriction on in vivo glucose uptake and insulin signaling of individual rat skeletal muscles by Sharma, Naveen, Sequea, Donel A, Castorena, Carlos M, Arias, Edward B, Qi, Nathan R, Cartee, Gregory D

“…Calorie restriction (CR) (consuming ~60% of ad libitum, AL, intake) improves whole body insulin sensitivity and enhances insulin-stimulated glucose uptake by…”
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SF-1 expression in the hypothalamus is required for beneficial metabolic effects of exercise by Fujikawa, Teppei, Castorena, Carlos M, Pearson, Mackenzie, Kusminski, Christine M, Ahmed, Newaz, Battiprolu, Pavan K, Kim, Ki Woo, Lee, Syann, Hill, Joseph A, Scherer, Philipp E, Holland, William L, Elmquist, Joel K

“…Exercise has numerous beneficial metabolic effects. The central nervous system (CNS) is critical for regulating energy balance and coordinating whole body…”
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