Search Results - "Castonguay, Jan"
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High susceptibility to fatty liver disease in two-pore channel 2-deficient mice
Published in Nature communications (21-08-2014)“…Endolysosomal organelles play a key role in trafficking, breakdown and receptor-mediated recycling of different macromolecules such as low-density lipoprotein…”
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2
The two-pore channel TPC1 is required for efficient protein processing through early and recycling endosomes
Published in Scientific reports (30-08-2017)“…Two-pore channels (TPCs) are localized in endo-lysosomal compartments and assumed to play an important role for vesicular fusion and endosomal trafficking…”
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3
Ablation of Ca(V)2.1 voltage-gated Ca²⁺ channels in mouse forebrain generates multiple cognitive impairments
Published in PloS one (2013)“…Voltage-gated Ca(V)2.1 (P/Q-type) Ca²⁺ channels located at the presynaptic membrane are known to control a multitude of Ca²⁺-dependent cellular processes such…”
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4
Clostridium difficile binary toxin CDT induces clustering of the lipolysis-stimulated lipoprotein receptor into lipid rafts
Published in mBio (30-04-2013)“…Clostridium difficile is the leading cause of antibiotics-associated diarrhea and pseudomembranous colitis. Hypervirulent C. difficile strains produce the…”
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Ablation of CaV2.1 Voltage-Gated Ca2+ Channels in Mouse Forebrain Generates Multiple Cognitive Impairments
Published in PloS one (31-10-2013)“…Voltage-gated CaV2.1 (P/Q-type) Ca2+ channels located at the presynaptic membrane are known to control a multitude of Ca2+-dependent cellular processes such as…”
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6
NAADP and the two-pore channel protein 1 participate in the acrosome reaction in mammalian spermatozoa
Published in Molecular biology of the cell (15-03-2014)“…The functional relationship between the formation of hundreds of fusion pores during the acrosome reaction in spermatozoa and the mobilization of calcium from…”
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Tetraspanin-13 modulates voltage-gated CaV2.2 Ca2+ channels
Published in Scientific reports (07-05-2013)“…Integration of voltage-gated Ca 2+ channels in a network of protein-interactions is a crucial requirement for proper regulation of channel activity. In this…”
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Correction: Ablation of Ca V 2.1 Voltage-Gated Ca 2+ Channels in Mouse Forebrain Generates Multiple Cognitive Impairments
Published in PloS one (30-12-2013)Get full text
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Correction: Ablation of CaV2.1 Voltage-Gated Ca2+ Channels in Mouse Forebrain Generates Multiple Cognitive Impairments
Published in PloS one (01-12-2013)“…The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript." (2013) Correction: Ablation of…”
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Correction: Ablation of Ca2.1 Voltage-Gated Ca Channels in Mouse Forebrain Generates Multiple Cognitive Impairments
Published in PloS one (01-01-2013)Get full text
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