Search Results - "Castillo, Karen"
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Molecular Determinants of BK Channel Functional Diversity and Functioning
Published in Physiological reviews (01-01-2017)“…Large-conductance Ca - and voltage-activated K (BK) channels play many physiological roles ranging from the maintenance of smooth muscle tone to hearing and…”
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2
Folic acid in carboxymethylcellulose/polyethylene oxide electrospun nanofibers: preparation, release and stability
Published in Journal of the science of food and agriculture (01-11-2024)“…BACKGROUND Folic acid (FA), a synthetically produced compound analogous to vitamin B9, also referred to as vitamin folate, is an essential compound in human…”
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3
Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons
Published in Autophagy (29-09-2013)“…Amyotrophic lateral sclerosis (ALS) is a fatal motoneuron disease with no current effective treatment. Accumulation of abnormal protein inclusions containing…”
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Correction: Prion Protein Misfolding Affects Calcium Homeostasis and Sensitizes Cells to Endoplasmic Reticulum Stress
Published in PloS one (11-01-2022)“…[This corrects the article DOI: 10.1371/journal.pone.0015658.]…”
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Hormesis: Protecting neurons against cellular stress in Parkinson disease
Published in Autophagy (01-06-2012)“…Protein folding stress is a salient feature of the most frequent neurodegenerative diseases. Although the accumulation of abnormally folded proteins is a…”
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Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis
Published in Autophagy (01-07-2014)“…Pharmacological activation of autophagy is becoming an attractive strategy to induce the selective degradation of aggregate-prone proteins. Recent evidence…”
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Amyotrophic lateral sclerosis pathogenesis: a journey through the secretory pathway
Published in Antioxidants & redox signaling (15-12-2010)“…Amyotrophic lateral sclerosis (ALS) is the most common adult-onset motoneuron degenerative disease characterized by the selective loss of motoneurons in the…”
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A journey from molecule to physiology and in silico tools for drug discovery targeting the transient receptor potential vanilloid type 1 (TRPV1) channel
Published in Frontiers in pharmacology (24-01-2024)“…The heat and capsaicin receptor TRPV1 channel is widely expressed in nerve terminals of dorsal root ganglia (DRGs) and trigeminal ganglia innervating the body…”
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Young Argentine Children's Attributions about Hypothetical Socially Withdrawn Peers
Published in The Journal of genetic psychology (01-07-2022)“…This study assessed young children's attributions about different subtypes of hypothetical socially withdrawn peers. Participants were N = 114 (56% boys, M age…”
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10
Large conductance voltage-and calcium-activated K + (BK) channel in health and disease
Published in Frontiers in pharmacology (2024)“…Large Conductance Voltage- and Calcium-activated K (BK) channels are transmembrane pore-forming proteins that regulate cell excitability and are also expressed…”
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11
Bisphosphonates Targeting Ion Channels and Musculoskeletal Effects
Published in Frontiers in pharmacology (15-03-2022)“…Bisphosphonates (BPs) are the most used bone-specific anti-resorptive agents, often chosen as first-line therapy in several bone diseases characterized by an…”
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12
Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress
Published in PloS one (29-12-2010)“…Prion-related disorders (PrDs) are fatal neurodegenerative disorders characterized by progressive neuronal impairment as well as the accumulation of an…”
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13
ROLE OF GLYCINE RECEPTORS IN THE NEUROIMMUNE MODULATION OF THE CHRONIC PAIN
Published in IBRO neuroscience reports (01-10-2023)Get full text
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14
Molecular mechanism underlying β1 regulation in voltage- and calcium-activated potassium (BK) channels
Published in Proceedings of the National Academy of Sciences - PNAS (14-04-2015)“…Being activated by depolarizing voltages and increases in cytoplasmic Ca2+, voltage- and calcium-activated potassium (BK) channels and their modulatory…”
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15
Eagle syndrome treated by a trans oral approach. Case report
Published in Cirugia y cirujanos (2021)“…Eagle syndrome is an uncommon condition, characterized by alteration in the stylomastoid process and sometimes a complete calcification of the stylohyoid…”
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Calcium-driven regulation of voltage-sensing domains in BK channels
Published in eLife (11-09-2019)“…Allosteric interactions between the voltage-sensing domain (VSD), the Ca -binding sites, and the pore domain govern the mammalian Ca - and voltage-activated K…”
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17
Lessons learned from a peer-supported diabetes education program in two dissimilar Mayan communities
Published in Frontiers in endocrinology (Lausanne) (04-01-2024)“…A steady rise in type 2 diabetes (T2D) in Mexico over the last 30 years has led to 11.5 million Mexicans being affected by this condition. There is an urgent…”
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18
TRPV1-Estradiol Stereospecific Relationship Underlies Cell Survival in Oxidative Cell Death
Published in Frontiers in physiology (26-05-2020)“…17β-estradiol is a neuronal survival factor against oxidative stress that triggers its protective effect even in the absence of classical estrogen receptors…”
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Physicochemical behaviour of a dinuclear uranyl complex formed with an octaphosphinoylated para-tert-butylcalix[8]arene. Spectroscopic studies in solution and in the solid state
Published in Polyhedron (17-02-2017)“…The octaphosphinoylated para-tert-butylcalix[8]arene (B8bL8) formed a dinuclear complex with uranyl nitrate. Spectroscopic results from UV–Vis, MIR, FIR, RD…”
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Incorporation of chia seeds (Salvia hispanica L.) in cereal flour mixtures: rheology and quality of sliced bread
Published in Dyna (Medellín, Colombia) (01-01-2021)“…Bread is a staple food in many countries of the world. The objective of this work was to include chia seeds (2-5%) in mixtures of wheat flour (71.5-81.5%),…”
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