Search Results - "Castillo, Izabella"

Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus by Adams, Cameron, Carbaugh, Derek L, Shu, Bo, Ng, Thiam-Seng, Castillo, Izabella N, Bhowmik, Ryan, Segovia-Chumbez, Bruno, Puhl, Ana C, Graham, Stephen, Diehl, Sean A, Lazear, Helen M, Lok, Shee-Mei, de Silva, Aravinda M, Premkumar, Lakshmanane

“…We currently have an incomplete understanding of why only a fraction of human antibodies that bind to flaviviruses block infection of cells. Here we define the…”
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Fc-mediated pan-sarbecovirus protection after alphavirus vector vaccination by Adams, Lily E., Leist, Sarah R., Dinnon, Kenneth H., West, Ande, Gully, Kendra L., Anderson, Elizabeth J., Loome, Jennifer F., Madden, Emily A., Powers, John M., Schäfer, Alexandra, Sarkar, Sanjay, Castillo, Izabella N., Maron, Jenny S., McNamara, Ryan P., Bertera, Harry L., Zweigart, Mark R., Higgins, Jaclyn S., Hampton, Brea K., Premkumar, Lakshmanane, Alter, Galit, Montgomery, Stephanie A., Baxter, Victoria K., Heise, Mark T., Baric, Ralph S.

“…Group 2B β-coronaviruses (sarbecoviruses) have caused regional and global epidemics in modern history. Here, we evaluate the mechanisms of cross-sarbecovirus…”
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Adjuvant-dependent impact of inactivated SARS-CoV-2 vaccines during heterologous infection by a SARS-related coronavirus by Dillard, Jacob A., Taft-Benz, Sharon A., Knight, Audrey C., Anderson, Elizabeth J., Pressey, Katia D., Parotti, Breantié, Martinez, Sabian A., Diaz, Jennifer L., Sarkar, Sanjay, Madden, Emily A., De la Cruz, Gabriela, Adams, Lily E., Dinnon, Kenneth H., Leist, Sarah R., Martinez, David R., Schäfer, Alexandra, Powers, John M., Yount, Boyd L., Castillo, Izabella N., Morales, Noah L., Burdick, Jane, Evangelista, Mia Katrina D., Ralph, Lauren M., Pankow, Nicholas C., Linnertz, Colton L., Lakshmanane, Premkumar, Montgomery, Stephanie A., Ferris, Martin T., Baric, Ralph S., Baxter, Victoria K., Heise, Mark T.

“…Whole virus-based inactivated SARS-CoV-2 vaccines adjuvanted with aluminum hydroxide have been critical to the COVID-19 pandemic response. Although these…”
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Investigation of the Host Kinome Response to Coronavirus Infection Reveals PI3K/mTOR Inhibitors as Betacoronavirus Antivirals by Fritch, Ethan J., Mordant, Angie L., Gilbert, Thomas S.K., Wells, Carrow I., Yang, Xuan, Barker, Natalie K., Madden, Emily A., Dinnon, Kenneth H., Hou, Yixuan J., Tse, Longping V., Castillo, Izabella N., Sims, Amy C., Moorman, Nathaniel J., Lakshmanane, Premkumar, Willson, Timothy M., Herring, Laura E., Graves, Lee M., Baric, Ralph S.

“…Host kinases play essential roles in the host cell cycle, innate immune signaling, the stress response to viral infection, and inflammation. Previous work has…”
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Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination by Voss, William N., Mallory, Michael L., Byrne, Patrick O., Marchioni, Jeffrey M., Knudson, Sean A., Powers, John M., Leist, Sarah R., Dadonaite, Bernadeta, Townsend, Douglas R., Kain, Jessica, Huang, Yimin, Satterwhite, Ed, Castillo, Izabella N., Mattocks, Melissa, Paresi, Chelsea, Munt, Jennifer E., Scobey, Trevor, Seeger, Allison, Premkumar, Lakshmanane, Bloom, Jesse D., Georgiou, George, McLellan, Jason S., Baric, Ralph S., Lavinder, Jason J., Ippolito, Gregory C.

“…We describe the molecular-level composition of polyclonal immunoglobulin G (IgG) anti-spike antibodies from ancestral severe acute respiratory syndrome…”
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Chikungunya-virus-specific CD4+ T cells are associated with chronic chikungunya viral arthritic disease in humans by Agarwal, Rimjhim, Chang, James, Cortes, Fernanda, Ha, Calvin, Villalpando, John, Castillo, Izabella, Galvez, Rosa, Grifoni, Alba, Sette, Alessandro, Romero-Vivas, Claudia, Heise, Mark, Premkumar, Lakshmanane, Falconar, Andrew, Weiskopf, Daniela

“…Chikungunya virus (CHIKV) is a mosquito-borne Alphavirus that causes recurrent outbreaks in tropical and subtropical regions of the world. In the first 2-7…”
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COVID-19 point-of-care tests can identify low-antibody individuals: In-depth immunoanalysis of boosting benefits in a healthy cohort by Mallory, Michael, Munt, Jennifer E, Narowski, Tara M, Castillo, Izabella, Cuadra, Edwing, Pisanic, Nora, Fields, Paul, Powers, John M, Dickson, Alexandria, Harris, Rohan, Wargowsky, Richard, Moran, Seamus, Allabban, Ahmed, Raphel, Kristin, McCaffrey, Timothy A, Brien, James D, Heaney, Christopher D, Lafleur, John E, Baric, Ralph S, Premkumar, Lakshmanane

“…The recommended COVID-19 booster vaccine uptake is low. At-home lateral flow assay (LFA) antigen tests are widely accepted for detecting infection during the…”
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