Search Results - "Castilho, Rachel O"
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Antileishmanial activity of standardized fractions of Stryphnodendron obovatum (Barbatimão) extract and constituent compounds
Published in Journal of ethnopharmacology (13-05-2015)“…Stryphnodendron obovatum Benth. is a Brazilian tree used to treat skin ulceration, promote wound healing, and inhibit the growth of protozoa, including…”
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Jacaranda cuspidifolia Mart. (Bignoniaceae) as an antibacterial agent
Published in Journal of medicinal food (01-12-2011)“…This study evaluated, in vitro, the antimicrobial activity of the hexane extract (JCHE), methanol extract (JCME), and chloroform fraction (JCCF) of bark from…”
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3
Chemical constituents of Distictella elongata (Vahl) Urb. (Bignoniaceae)
Published in Anais da Academia Brasileira de Ciências (01-09-2013)“…Pectolinarin, a flavone heteroside, was isolated from Distictella elongata (Vahl) Urb. leaves ethanol extract, along with a mixture of ursolic, pomolic and…”
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4
Chitosan/hydroxyethyl cellulose inserts for sustained-release of dorzolamide for glaucoma treatment: In vitro and in vivo evaluation
Published in International journal of pharmaceutics (30-10-2019)“…[Display omitted] Eye drops containing hydrophilic drugs are commonly used to reduce intraocular pressure (IOP) in glaucoma patients, but compliance to the…”
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Propolis--based chitosan varnish: drug delivery, controlled release and antimicrobial activity against oral pathogen bacteria
Published in BMC complementary and alternative medicine (12-12-2014)“…Dental caries is the most prevalent oral disease in several Asian and Latin American countries. It is an infectious disease and different types of bacteria are…”
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Antithrombotic potential of Lippia alba: A mechanistic approach
Published in Journal of ethnopharmacology (30-01-2023)“…Lippia alba (Mill.) N.E.Br. ex Britton & P. Wilson is traditionally used in Brazil as an adjunct in the relief of mild anxiety, as an antispasmodic, and as an…”
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The rationality involved in the popular use of coffee (Coffea sp) and sunflower seed (Helianthus annuus) for the treatment of vitiligo: a case report
Published in Explore (New York, N.Y.) (01-09-2022)“…•The treatments available for vitiligo have many adverse effects and/or contraindications;•Natural alternatives such as mamacadela (Brosimum gaudichaudii) are…”
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New mesalamine polymeric conjugate for controlled release: Preparation, characterization and biodistribution study
Published in European journal of pharmaceutical sciences (01-01-2018)“…Mesalamine (5-ASA) consists of the first-line therapy for the treatment of ulcerative colitis; however, it has low bioavailability, can cause several systemic…”
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Poloxamer 407 (Pluronic® F127)-based polymeric micelles for amphotericin B: In vitro biological activity, toxicity and in vivo therapeutic efficacy against murine tegumentary leishmaniasis
Published in Experimental parasitology (01-10-2016)“…In the present study, a Poloxamer 407-based amphotericin B (AmpB)-containing polymeric micelles system (AmpB/M) was employed in the treatment of Leishmania…”
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Use of chitosan as pharmaceutical excipient in ocular drug delivery systems: Sterilization and pharmacokinetics
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-07-2020)“…The use of chitosan as a pharmaceutical excipient in the ocular field is already established. Nevertheless, some aspects related to its ocular administration,…”
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Poloxamer 407 (Pluronic(®) F127)-based polymeric micelles for amphotericin B: In vitro biological activity, toxicity and in vivo therapeutic efficacy against murine tegumentary leishmaniasis
Published in Experimental parasitology (01-10-2016)“…In the present study, a Poloxamer 407-based amphotericin B (AmpB)-containing polymeric micelles system (AmpB/M) was employed in the treatment of Leishmania…”
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12
Thrombin generation test with the calibrated automated thrombogram and anticoagulant activity of Mentha crispa
Published in Blood coagulation & fibrinolysis (01-01-2020)“…Evaluate the in-vitro effect of Mentha crispa extract on blood coagulation, compare the conventional coagulometric tests with thrombin generation test (TGT),…”
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In Vitro TNF-α Inhibitory Activity of Brazilian Plants and Anti-Inflammatory Effect of Stryphnodendron adstringens in an Acute Arthritis Model
Published in Evidence-based complementary and alternative medicine (01-01-2016)“…Stryphnodendron species, popularly named “barbatimão,” are traditionally used in Brazil as anti-inflammatory agents. This study aimed to investigate the effect…”
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14
Antileishmanial activity and cytotoxicity of Brazilian plants
Published in Experimental parasitology (01-08-2014)“…[Display omitted] •Brazilian medicinal plants were evaluated against L. amazonensis.•D. alata and J. cuspidifolia leaves had high selectivity index.•These…”
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Antileishmanial activity and mechanism of action from a purified fraction of Zingiber officinalis Roscoe against Leishmania amazonensis
Published in Experimental parasitology (01-07-2016)“…In recent years, considerable attention has been given to identify new antileishmanial products derived from medicinal plants, although, to date, no new…”
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Warfarin Safety: A Cross-Sectional Study of the Factors Associated with the Consumption of Medicinal Plants in a Brazilian Anticoagulation Clinic
Published in American journal of cardiovascular drugs : drugs, devices, and other interventions (01-06-2018)“…Objective The aim of this study was to analyze factors associated with the consumption of medicinal plants by patients being treated with warfarin in a…”
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Evaluation of the Effects of Some Brazilian Medicinal Plants on the Production of TNF-α and CCL2 by THP-1 Cells
Published in Evidence-based complementary and alternative medicine (01-01-2015)“…Several plant species are traditionally used in Brazil to treat various inflammatory diseases. Tumor necrosis factor- (TNF-) α and chemokine (C-C motif) ligand…”
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Development and Validation of a High Performance Liquid Chromatographic Method for Determination of Bimatoprost in Chitosan-Based Ocular Inserts
Published in Analytical letters (11-02-2015)“…Glaucoma is one of the most prominent causes of blindness around the world. Conventional eye-drops, currently used in the treatment of the disease, must be…”
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Prophylactic or therapeutic administration of Agaricus blazei Murill is effective in treatment of murine visceral leishmaniasis
Published in Experimental parasitology (01-10-2012)“…[Display omitted] ► Leishmanicidal activity from fractions purified from Agaricus blazei extract (AbM). ► Treatment of BALB/c mice infected with Leishmania…”
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Recent progess in phytotherapy: A Brazilian perspective
Published in European journal of integrative medicine (01-01-2021)“…Phytotherapy has very old origins and it is based on the use of medicinal plants to treat and prevent diseases. Brazil, because it is a country with wide…”
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