Search Results - "Castiglioni, Victoria G."
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Caenorhabditis elegans LET-413 Scribble is essential in the epidermis for growth, viability, and directional outgrowth of epithelial seam cells
Published in PLoS genetics (21-10-2021)“…The conserved adapter protein Scribble (Scrib) plays essential roles in a variety of cellular processes, including polarity establishment, proliferation, and…”
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Epidermal PAR-6 and PKC-3 are essential for larval development of C. elegans and organize non-centrosomal microtubules
Published in eLife (10-12-2020)“…The cortical polarity regulators PAR-6, PKC-3, and PAR-3 are essential for the polarization of a broad variety of cell types in multicellular animals. In , the…”
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New insights into apical-basal polarization in epithelia
Published in Current opinion in cell biology (01-02-2020)“…The establishment of an apical–basal axis of polarity is essential for the organization and functioning of epithelial cells. Polarization of epithelial cells…”
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Orsay virus infection increases Caenorhabditis elegans resistance to heat-shock
Published in Biology letters (2005) (01-08-2024)“…The heat-shock response plays a key role in the immune defence against viruses across various organisms. Studies on model organisms have shown that inducing…”
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Identification and characterization of Crumbs polarity complex proteins in Caenorhabditis elegans
Published in The Journal of biological chemistry (01-04-2022)“…Crumbs proteins are evolutionarily conserved transmembrane proteins with essential roles in promoting the formation of the apical domain in epithelial cells…”
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Experimental evolution of an RNA virus in Caenorhabditis elegans
Published in Infection, genetics and evolution (01-09-2024)“…The discovery of Orsay virus (OrV), the first virus infecting wild populations of Caenorhabditis elegans, has boosted studies of viral immunity pathways in…”
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Story of an infection: Viral dynamics and host responses in the Caenorhabditis elegans -Orsay virus pathosystem
Published in Science advances (27-09-2024)“…Orsay virus (OrV) is the only known natural virus affecting , with minimal impact on the animal's fitness due to its robust innate immune response. This study…”
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