Search Results - "Castiglione, Stefania"
-
1
MicroRNA-34a: the bad guy in age-related vascular diseases
Published in Cellular and molecular life sciences : CMLS (01-12-2021)“…The age-related vasculature alteration is the prominent risk factor for vascular diseases (VD), namely, atherosclerosis, abdominal aortic aneurysm, vascular…”
Get full text
Journal Article -
2
Effects of RAGE Deletion on the Cardiac Transcriptome during Aging
Published in International journal of molecular sciences (22-09-2022)“…Cardiac aging is characterized by increased cardiomyocyte hypertrophy, myocardial stiffness, and fibrosis, which enhance cardiovascular risk. The receptor for…”
Get full text
Journal Article -
3
BPIFB4 and its longevity-associated haplotype protect from cardiac ischemia in humans and mice
Published in Cell death & disease (15-08-2023)“…Long-living individuals (LLIs) escape age-related cardiovascular complications until the very last stage of life. Previous studies have shown that a…”
Get full text
Journal Article -
4
Circulating levels of AGEs and soluble RAGE isoforms are associated with all-cause mortality and development of cardiovascular complications in type 2 diabetes: a retrospective cohort study
Published in Cardiovascular diabetology (06-06-2022)“…Advanced glycation end-products (AGEs) and their interaction with the receptor for advanced glycation end-products (RAGE) play a pivotal role in the…”
Get full text
Journal Article -
5
High Phosphate-Induced JAK-STAT Signalling Sustains Vascular Smooth Muscle Cell Inflammation and Limits Calcification
Published in Biomolecules (Basel, Switzerland) (01-01-2024)“…Vascular calcification (VC) is an age-related complication characterised by calcium-phosphate deposition in the arterial wall driven by the osteogenic…”
Get full text
Journal Article -
6
Abstract 3079: The antitumoral activity of metformin in glioblastoma stem cells is mediated by tmCLIC1 protein
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Abstract Glioblastoma (GB) is the deadliest brain tumor, representing a major clinical challenge in the field. Despite standard of care together with…”
Get full text
Journal Article -
7
Abstract 1200: Long-duration term TTFields treatment of glioblastoma cells induces cell death
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Abstract Glioblastoma is the most aggressive among brain tumors. Radiotherapy and chemotherapy, as adjuvanttreatments after surgical removal of the tumor mass,…”
Get full text
Journal Article -
8
Human antimicrobial peptide LL-37 contributes to Alzheimer’s disease progression
Published in Molecular psychiatry (01-11-2022)“…As a prime mover in Alzheimer’s disease (AD), microglial activation requires membrane translocation, integration, and activation of the metamorphic protein…”
Get full text
Journal Article -
9
High phosphate-induced JAK-STAT signalling sustains Vascular Smooth Muscle Cells inflammation and limits calcification
Published in Vascular pharmacology (01-06-2024)Get full text
Journal Article -
10
Correction to: Human antimicrobial peptide LL-37 contributes to Alzheimer’s disease progression
Published in Molecular psychiatry (2024)Get full text
Journal Article -
11
STEM-10. LONG-LASTING TUMOR TREATING FIELDS (TTFIELDS) STIMULATION OF GLIOBLASTOMA PRIMARY CULTURE DAMAGES PREFERENTIALLY FULLY DIFFERENTIATED CANCER CELLS
Published in Neuro-oncology (Charlottesville, Va.) (09-11-2020)“…Abstract Glioblastoma (GBM) is the most aggressive among brain tumors. Radiotherapy and chemotherapy as adjuvant procedures after surgical removal of the tumor…”
Get full text
Journal Article -
12
Abstract We140: Age-Dependent miR-34a and AGTRAP Cross-Modulation: a Novel Mechanism of Vascular Aging
Published in Circulation research (02-08-2024)“…Abstract only Background: Renin-Angiotensin Aldosterone System (RAAS) activation plays a central role in vascular aging, leading to structural and functional…”
Get full text
Journal Article -
13
Modulation of soluble receptor for advanced glycation end products isoforms and advanced glycation end products in long-living individuals
Published in Biomarkers in medicine (01-08-2021)“…Circulating levels of soluble receptor for advanced glycation end products (sRAGE) and advanced glycation end products (AGEs) correlate with…”
Get full text
Journal Article -
14
Abstract 2315: Synergic antitumoral activity of TTFields stimulation and Chloride Intracellular Channel 1 (CLIC1) inhibition in human glioblastoma primary culture
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Glioblastoma relapse inevitably occurs in the majority of patients after surgery. Chemo- and radio- therapy are in most cases ineffective, while Tumor…”
Get full text
Journal Article -
15
Soluble Receptor for Advanced Glycation End-products regulates age-associated Cardiac Fibrosis
Published in International journal of biological sciences (01-01-2021)“…Myocardial aging increases the cardiovascular risk in the elderly. The Receptor for Advanced Glycation End-products (RAGE) is involved in age-related…”
Get full text
Journal Article -
16
Abstract 1425: TTFields reduce sensitivity in glioblastoma is associated with the functional expression of the chloride intracellular channel 1 and with voltage dependent sodium channel
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Glioblastoma (GBM) is the most aggressive type of brain tumor, and existing treatments are inadequate at preventing recurrence. Tumor Treating Fields…”
Get full text
Journal Article -
17
Abstract 903: Metformin antitumoral activity is exclusively mediated by the membrane functional expression of the Chloride Intracellular Channel 1 in glioblastoma stem cells
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Glioblastoma (GB) is the deadliest brain tumor, representing a major clinical challenge in the field. Despite standard of care together with…”
Get full text
Journal Article -
18
Diagnostic accuracy of confocal laser endomicroscopy in diagnosing dysplasia in patients affected by long-standing ulcerative colitis
Published in World journal of gastrointestinal endoscopy (16-09-2012)“…AIM:To evaluate the diagnostic accuracy of confocal laser endomicroscopy(CLE) for the detection of dysplasia in long-standing ulcerative colitis(UC).METHODS:We…”
Get full text
Journal Article