Search Results - "Castiglia, Virginia"
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Innate immune response to Streptococcus pyogenes depends on the combined activation of TLR13 and TLR2
Published in PloS one (10-03-2015)“…Innate immune recognition of the major human-specific Gram-positive pathogen Streptococcus pyogenes is not understood. Here we show that mice employ Toll-like…”
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Crucial Role of Nucleic Acid Sensing via Endosomal Toll-Like Receptors for the Defense of Streptococcus pyogenes in vitro and in vivo
Published in Frontiers in immunology (21-02-2019)“…is a major human pathogen causing a variety of diseases ranging from common pharyngitis to life-threatening soft tissue infections and sepsis. Microbial…”
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Rhinoscleroma pathogenesis: The type K3 capsule of Klebsiella rhinoscleromatis is a virulence factor not involved in Mikulicz cells formation
Published in PLoS neglected tropical diseases (01-01-2018)“…Rhinoscleroma is a human specific chronic granulomatous infection of the nose and upper airways caused by the Gram-negative bacterium Klebsiella pneumoniae…”
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Correction: Caffeine Prevents Transcription Inhibition and P-TEFb/7SK Dissociation Following UV-Induced DNA Damage
Published in PloS one (07-10-2013)Get full text
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Caffeine prevents transcription inhibition and P-TEFb/7SK dissociation following UV-induced DNA damage
Published in PloS one (21-06-2010)“…The mechanisms by which DNA damage triggers suppression of transcription of a large number of genes are poorly understood. DNA damage rapidly induces a release…”
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Type I Interferons in Bacterial Infections: A Balancing Act
Published in Frontiers in immunology (26-12-2016)“…Defense against bacterial infections requires activation of the immune response as well as timely reestablishment of tissue and immune homeostasis…”
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Type I Interferon Signaling Prevents IL-1β-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue
Published in Cell host & microbe (09-03-2016)“…Type I interferons (IFN-Is) are fundamental for antiviral immunity, but their role in bacterial infections is contradictory and incompletely described…”
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21: Essential function of type I IFN signaling in balancing inflammation during Streptococcus pyogenes infection
Published in Cytokine (Philadelphia, Pa.) (01-11-2014)“…Streptococcus pyogenes also known as Group A Streptoccocus (GAS) is a common human pathogen responsible of a variety of diseases that range from mild…”
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Innate Immune Response to Streptococcus pyogenes Depends on the Combined Activation of TLR13 and TLR2
Published in PloS one (10-03-2015)“…Innate immune recognition of the major human-specific Gram-positive pathogen Strepto-coccus pyogenes is not understood. Here we show that mice employ Toll-like…”
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Innate Immune Response to Streptococcus pyogenes Depends on the Combined Activation of TLR13 and TLR2: e0119727
Published in PloS one (01-03-2015)“…Innate immune recognition of the major human-specific Gram-positive pathogen Streptococcus pyogenes is not understood. Here we show that mice employ Toll-like…”
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