Search Results - "Casti, Alberto"
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Male and female rats differ in brain cannabinoid CB1 receptor density and function and in behavioural traits predisposing to drug addiction: effect of ovarian hormones
Published in Current pharmaceutical design (01-04-2014)“…Sex-dependent differences are frequently observed in the biological and behavioural effects of substances of abuse, including cannabis. We recently…”
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Δ9-tetrahydrocannabinol prevents methamphetamine-induced neurotoxicity
Published in PloS one (20-05-2014)“…Methamphetamine (METH) is a potent psychostimulant with neurotoxic properties. Heavy use increases the activation of neuronal nitric oxide synthase (nNOS),…”
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Oxytocin immunoreactivity in the human urethral (Littre's) glands
Published in Journal of Reproduction and Development (01-02-2010)“…Oxytocin is a cyclic nonapeptide whose best known effects are stimulation of uterine smooth muscle cells during labor and of milk ejection during lactation…”
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STZ‐diabetic rat heart maintains developed tension amplitude by increasing sarcomere length and crossbridge density
Published in Experimental physiology (01-07-2021)“…New Findings What is the central question of this study? In the papillary muscle from type I diabetic rats, does diabetes‐associated altered ventricular…”
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Targeting neurosteroid synthesis as a therapy for schizophrenia-related alterations induced by early psychosocial stress
Published in Schizophrenia research (01-11-2015)“…Abstract Background Cogent evidence has shown that schizophrenia vulnerability is enhanced by psychosocial stress in adolescence, yet the underpinnings of this…”
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Regional distribution of 5α-reductase type 2 in the adult rat brain: An immunohistochemical analysis
Published in Psychoneuroendocrinology (01-02-2013)“…Summary The enzyme 5α-reductase (5αR) catalyzes the conversion of testosterone and other Δ4 - 3-ketosteroids into their 5α-reduced metabolites. Of the five…”
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Enhanced endocannabinoid-mediated modulation of rostromedial tegmental nucleus drive onto dopamine neurons in Sardinian alcohol-preferring rats
Published in The Journal of neuroscience (17-09-2014)“…The progressive predominance of rewarding effects of addictive drugs over their aversive properties likely contributes to the transition from drug use to drug…”
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Synthesis and Pharmacological Characterization of 2‑(Acylamino)thiophene Derivatives as Metabolically Stable, Orally Effective, Positive Allosteric Modulators of the GABAB Receptor
Published in Journal of medicinal chemistry (09-05-2013)“…Two recently reported hit compounds, COR627 and COR628, underpinned the development of a series of 2-(acylamino)thiophene derivatives. Some of these compounds…”
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The aggression and behavioral abnormalities associated with monoamine oxidase A deficiency are rescued by acute inhibition of serotonin reuptake
Published in Journal of psychiatric research (01-09-2014)“…Abstract The termination of serotonin (5-hydroxytryptamine, 5-HT) neurotransmission is regulated by its uptake by the 5-HT transporter (5-HTT), as well as its…”
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9-Tetrahydrocannabinol Prevents Methamphetamine-Induced Neurotoxicity
Published in PloS one (20-05-2014)“…Methamphetamine (METH) is a potent psychostimulant with neurotoxic properties. Heavy use increases the activation of neuronal nitric oxide synthase (nNOS),…”
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Regional distribution of 5[alpha]-reductase type 2 in the adult rat brain: An immunohistochemical analysis
Published in Psychoneuroendocrinology (01-02-2013)“…The enzyme 5[alpha]-reductase (5[alpha]R) catalyzes the conversion of testosterone and other I4-3-ketosteroids into their 5[alpha]-reduced metabolites. Of the…”
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12
Electron microscopic immunogold localization of statherin in human minor salivary glands
Published in Journal of anatomy (01-05-2010)“…In this study, which supplements a recent article on the localization of statherin in human major salivary glands, we investigated the intracellular…”
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Epidemiology of Osteoporosis in an Isolated Sardinian Population by Using Quantitative Ultrasound
Published in American journal of epidemiology (15-08-2011)“…This study aimed at estimating the prevalence of osteoporosis and osteopenia in a Sardinian isolated population using hand quantitative ultrasound and at…”
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Effects of Topiramate on the Prepulse Inhibition of the Acoustic Startle in Rats
Published in Neuropsychopharmacology (New York, N.Y.) (01-02-2007)“…The anticonvulsant topiramate (TPM) has been recently proposed as a novel adjuvant therapy for bipolar disorder and schizophrenia, yet its efficacy remains…”
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Genetic architecture of hand quantitative ultrasound measures: A population-based study in a Sardinian genetic isolate
Published in Bone (New York, N.Y.) (01-04-2010)“…Abstract It is now recognized that quantitative ultrasound (QUS) measures may predict osteoporotic fracture risk independently of bone mineral density…”
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Activation of D1, but not D2 receptors potentiates dizocilpine-mediated disruption of prepulse inhibition of the startle
Published in Neuropsychopharmacology (New York, N.Y.) (01-03-2005)“…Although substantial evidence has shown interactions between glutamatergic and dopaminergic systems play a cardinal role in the regulation of attentional…”
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Prenatal exposure to a cannabinoid receptor agonist does not affect sensorimotor gating in rats
Published in European journal of pharmacology (15-02-2006)“…Clinical evidence suggests that prenatal exposure to cannabis may be conducive to long-term neurobehavioral impairments in executive and attentional domains…”
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