Search Results - "Castellucci, Léa Cristina"

Short communication: The miR-155a-5p is correlated with increased ROS and impaired apoptosis in macrophages infected by Leishmania braziliensis by Lago, Tainã, Cardoso, Thyago Marconi, Rocha, Alan, Carvalho, Edgar M, Castellucci, Léa Cristina

“…Cutaneous leishmaniasis (CL) caused by Leishmania braziliensis, is a disease characterized by well-limited ulcerated lesions with raised borders in exposed…”
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MicroRNAs regulating macrophages infected with Leishmania L. ( V. ) Braziliensis isolated from different clinical forms of American tegumentary leishmaniasis by Lago, Tainã, Medina, Lilian, Lago, Jamile, Santana, Nadja, Cardoso, Thiago, Rocha, Alan, Leal-Calvo, Thyago, Carvalho, Edgar M, Castellucci, Léa Cristina

“…Leishmaniasis is an infectious disease caused by protozoa of the genus . There are still no vaccines, and therapeutic options are limited, indicating the…”
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The miRNA 361-3p, a Regulator of GZMB and TNF Is Associated With Therapeutic Failure and Longer Time Healing of Cutaneous Leishmaniasis Caused by L. (viannia) braziliensis by Lago, Tainã S, Silva, Juliana Almeida, Lago, Ednaldo L, Carvalho, Edgar M, Zanette, Dalila L, Castellucci, Léa Cristina

“…infection causes American Tegumentary Leishmaniasis (ATL), with prolonged time to healing lesions. The potent inflammatory response developed by the host is…”
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Whole blood profiling of leprosy type 1(reversal) reactions highlights prominence of innate immune response genes by Rêgo, Jamile Leão, de Lima Santana, Nadja, Machado, Paulo Roberto Lima, Ribeiro-Alves, Marcelo, de Toledo-Pinto, Thiago Gomes, Castellucci, Léa Cristina, Moraes, Milton Ozório

“…The major factors contributing for nerve damage and permanent disabilities in leprosy are type 1 or reversal reactions (RR) and type 2 or erythema nodosum…”
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FLI1 gene influences lesion size and skin test may predict therapeutic response in cutaneous leishmaniasis by da Hora, Anadilton Santos, de Almeida, Lucas Frederico, do Lago, Tainã Souza, Machado, Paulo Roberto, Castellucci, Léa Cristina

“…Genes associated with wound healing have been shown to be risk factors for cutaneous leishmaniasis (CL) which is caused by Leishmania braziliensis. In this…”
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Host genetic factors in American cutaneous leishmaniasis: a critical appraisal of studies conducted in an endemic area of Brazil by Castellucci, Léa Cristina, de Almeida, Lucas Frederico, Jamieson, Sarra Elisabeth, Fakiola, Michaela, de Carvalho, Edgar Marcelino, Blackwell, Jenefer Mary

“…American cutaneous leishmaniasis (ACL) is a vector-transmitted infectious disease with an estimated 1.5 million new cases per year. In Brazil, ACL represents a…”
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Polymorphism in the interleukin-10 gene is associated with overactive bladder phenotype associated with HTLV-1 infection by Braz, Marcos, Oliveira, Joyce Moura, Rêgo, Jamile Leão, Carvalho, Edgar Marcelino de, Santos, Silvane Maria Braga, Castellucci, Léa Cristina

“…Human T-cell lymphotropic virus type 1 (HTLV-1)-associated inflammatory diseases are not well understood; however, their clinical manifestations may be…”
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Polymorphisms in genes TLR1, 2 and 4 are associated with differential cytokine and chemokine serum production in patients with leprosy by Santana, Nadja de Lima, Rêgo, Jamile Leão, Oliveira, Joyce Moura, Almeida, Lucas Frederico de, Braz, Marcos, Machado, Lídia Maria Medeiros, Machado, Paulo Roberto Lima, Castellucci, Léa Cristina

“…Leprosy or hansen's disease is a spectral disease whose clinical forms mostly depends on host's immune and genetic factors. Different Toll-like receptors (TLR)…”
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The role of ERBB2 gene polymorphisms in leprosy susceptibility by Rêgo, Jamile Leão, Oliveira, Joyce Moura, de Lima Santana, Nadja, Machado, Paulo Roberto Lima, Castellucci, Léa Cristina

“…Mycobacterium leprae infects skin and peripheral nerves causing deformities and disability. The M. leprae bacterium binds to ErbB2 on the Schwann cell surface…”
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MicroRNAs correlate with bacillary index and genes associated to cell death processes in leprosy by de Lima Santana, Nadja, Neves de Farias, Lucas, Lago, Tainã, Leal-Calvo, Thyago, Lima Machado, Paulo Roberto, Castellucci, Léa Cristina

“…Mycobacterium leprae infects skin and peripheral nerves causing a broad of clinical forms. MicroRNAs (miRNAs) control immune mechanisms such as apoptosis,…”
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Serum immune markers as triggers of reactional episodes in multibacillary patients with leprosy by Rego, Jamile Leao, Santana, Nadja de Lima, Aguiar, Eric Roberto, Queiroz, Ivonete Santos, Carvalho, Lucas Pedreira de, Machado, Paulo Roberto Lima, Castellucci, Lea Cristina

“…Introduction: The development of leprosy reactions is one of the main challenges in the management of patients with leprosy. The reactions can be divided into…”
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Polymorphisms in genes TLR1, 2 and 4 are associated with differential cytokine and chemokine serum production in patients with leprosy by Santana, Nadja de Lima, Rêgo, Jamile Leão, Oliveira, Joyce Moura, Almeida, Lucas Frederico de, Braz, Marcos, Machado, Lídia Maria Medeiros, Machado, Paulo Roberto Lima, Castellucci, Léa Cristina

“…BACKGROUND Leprosy or hansen's disease is a spectral disease whose clinical forms mostly depends on host's immune and genetic factors. Different Toll-like…”
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Putative pathogen-selected polymorphisms in the PKLR gene are associated with mycobacterial susceptibility in Brazilian and African populations by Bezerra, Ohanna Cavalcanti de Lima, Alvarado-Arnez, Lucia Elena, Mabunda, Nédio, Salomé, Graça, de Sousa, Amina, Kehdy, Fernanda de Souza Gomes, Sales-Marques, Carolinne, Manta, Fernanda Saloum de Neves, Andrade, Rafaela Mota, Ferreira, Laís Pereira, Leal-Calvo, Thyago, Cardoso, Cynthia Chester, Nunes, Kelly, Gouveia, Mateus H, Mbulaiteve, Sam M, Yeboah, Edward D, Hsing, Ann, Latini, Ana Carla Pereira, Leturiondo, André Luiz, Rodrigues, Fabíola da Costa, Noronha, Ariani Batista, Ferreira, Cynthia de Oliveira, Talhari, Carolina, Rêgo, Jamile Leão, Castellucci, Léa Cristina de Carvalho, Tarazona-Santos, Eduardo, Carvalho, Elizeu Fagundes de, Meyer, Diogo, Pinheiro, Roberta Olmo, Jani, Ilesh V, Pacheco, Antonio Guilherme, Moraes, Milton Ozório

“…Pyruvate kinase (PK), encoded by the PKLR gene, is a key player in glycolysis controlling the integrity of erythrocytes. Due to Plasmodium selection, mutations…”
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