Search Results - "Castelloe, E"

28 AN INTERNATIONAL STUDY EVALUATING THE FARNESOID X RECEPTOR AGONIST OBETICHOLIC ACID AS MONOTHERAPY IN PBC by Kowdley, K.V, Jones, D, Luketic, V, Chapman, R, Burroughs, A, Hirschfield, G, Poupon, R, Schramm, C, Vincent, C, Rust, C, Pares, A, Mason, A, Sciacca, C, Beecher-Jones, T, Bohm, O, Castelloe, E, Pruzanski, M, Shapiro, D

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2 FARNESOID-X RECEPTOR AGONISTS: A NEW CLASS OF DRUGS FOR THE TREATMENT OF PBC? AN INTERNATIONAL STUDY EVALUATING THE ADDITION OF INT-747 TO URSODEOXYCHOLIC ACID by Mason, A, Luketic, V, Lindor, K, Hirschfield, G, Gordon, S, Mayo, M, Kowdley, K, Parés, A, Trauner, M, Castelloe, E, Sciacca, C, Jones, T.B, Böhm, O, Shapiro, D

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468 UNIQUE PATTERN OF VIROLOGIC RESPONSE IN PATIENTS WITH GENOTYPE-1 HCV: A PHASE II STUDY OF CTS-1027 IN COMBINATION WITH PEGINTERFERON/RIBAVIRIN (SOC) IN NULL RESPONDERS by Rodriguez-Torres, M, Bacon, B, Gordon, S, Rubin, R, Box, T, Kugelmas, M, Vierling, J, Yoffe, B, Pockros, P, Everson, G, Jonas, M, Balart, L, Bohm, O, Castelloe, E, Huyghe, M.R, Mento, S, Spada, A, Fox, A.W, Chojkier, M

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410 24-WEEK TREATMENT WITH CTS-1027 IN COMBINATION WITH RIBAVIRIN REDUCES HCV-RNA IN TREATMENT NAIVE GENOTYPE-1 PATIENTS by Chojkier, M, Everson, G, Muir, A, Bacon, B, Rodriguez-Torres, M, Bennett, M, Fried, M, Gordon, S, Gross, J, Nelson, D, Balart, L, Jonas, M, Szabo, G, Bloomer, J, McCullough, A, Nyberg, L, Smith, C, Bohm, O, Fox, A.W, Castelloe, E, Huyghe, M, Mento, S, Spada, A

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Efficacy and Safety of the Farnesoid X Receptor Agonist Obeticholic Acid in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease by Mudaliar, Sunder, Henry, Robert R, Sanyal, Arun J, Morrow, Linda, Marschall, Hanns–Ulrich, Kipnes, Mark, Adorini, Luciano, Sciacca, Cathi I, Clopton, Paul, Castelloe, Erin, Dillon, Paul, Pruzanski, Mark, Shapiro, David

“…Background & Aims Obeticholic acid (OCA; INT-747, 6α-ethyl-chenodeoxycholic acid) is a semisynthetic derivative of the primary human bile acid chenodeoxycholic…”
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Efficacy of Obeticholic Acid in Patients With Primary Biliary Cirrhosis and Inadequate Response to Ursodeoxycholic Acid by Hirschfield, Gideon M, Mason, Andrew, Luketic, Velimir, Lindor, Keith, Gordon, Stuart C, Mayo, Marlyn, Kowdley, Kris V, Vincent, Catherine, Bodhenheimer, Henry C, Parés, Albert, Trauner, Michael, Marschall, Hanns-Ulrich, Adorini, Luciano, Sciacca, Cathi, Beecher-Jones, Tessa, Castelloe, Erin, Böhm, Olaf, Shapiro, David

“…Background & Aims We evaluated the efficacy and safety of obeticholic acid (OCA, α-ethylchenodeoxycholic acid) in a randomized controlled trial of patients…”
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Safety Pharmacology in Drug Discovery and Development by Morimoto, Bruce H, Castelloe, Erin, Fox, Anthony W

“…Safety pharmacology is essential throughout the spectrum of drug discovery and development. Prior to first-in-human studies, safety pharmacology assays, tests,…”
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