Search Results - "Castellino, Sharon M."

Brentuximab Vedotin with Chemotherapy in Pediatric High-Risk Hodgkin’s Lymphoma by Castellino, Sharon M., Pei, Qinglin, Parsons, Susan K., Hodgson, David, McCarten, Kathleen, Horton, Terzah, Cho, Steve, Wu, Yue, Punnett, Angela, Dave, Hema, Henderson, Tara O., Hoppe, Bradford S., Charpentier, Anne-Marie, Keller, Frank G., Kelly, Kara M.

“…A regimen substituting brentuximab vedotin for bleomycin improved 3-year event-free survival among children and adolescents with Hodgkin’s lymphoma by nearly…”
Get full text

Validity and Reliability of the Pediatric Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events by Reeve, Bryce B, McFatrich, Molly, Mack, Jennifer W, Maurer, Scott H, Jacobs, Shana S, Freyer, David R, Withycombe, Janice S, Baker, Justin N, Castellino, Sharon M, Lin, Li, Lucas, Nicole R, Hinds, Pamela S

“…Abstract Background Patient-reported outcome (PRO) measurements linked to Common Terminology Criteria for Adverse Events (CTCAE) grading may improve symptom…”
Get full text

Delineating the age ranges used to define adolescents and young adults by Geiger, Ann M, Castellino, Sharon M

Get full text

Morbidity and mortality in long-term survivors of Hodgkin lymphoma: a report from the Childhood Cancer Survivor Study by Castellino, Sharon M., Geiger, Ann M., Mertens, Ann C., Leisenring, Wendy M., Tooze, Janet A., Goodman, Pam, Stovall, Marilyn, Robison, Leslie L., Hudson, Melissa M.

“…The contribution of specific cancer therapies, comorbid medical conditions, and host factors to mortality risk after pediatric Hodgkin lymphoma (HL) is…”
Get full text

Hyaluronan Synthase 3 Variant and Anthracycline-Related Cardiomyopathy: A Report From the Children's Oncology Group by Wang, Xuexia, Liu, Wei, Sun, Can-Lan, Armenian, Saro H, Hakonarson, Hakon, Hageman, Lindsey, Ding, Yan, Landier, Wendy, Blanco, Javier G, Chen, Lu, Quiñones, Adolfo, Ferguson, Daniel, Winick, Naomi, Ginsberg, Jill P, Keller, Frank, Neglia, Joseph P, Desai, Sunil, Sklar, Charles A, Castellino, Sharon M, Cherrick, Irene, Dreyer, ZoAnn E, Hudson, Melissa M, Robison, Leslie L, Yasui, Yutaka, Relling, Mary V, Bhatia, Smita

“…The strong dose-dependent association between anthracyclines and cardiomyopathy is further exacerbated by the co-occurrence of cardiovascular risk factors…”
Get full text

Single-cell analysis reveals altered tumor microenvironments of relapse- and remission-associated pediatric acute myeloid leukemia by Mumme, Hope, Thomas, Beena E., Bhasin, Swati S., Krishnan, Upaasana, Dwivedi, Bhakti, Perumalla, Pruthvi, Sarkar, Debasree, Ulukaya, Gulay B., Sabnis, Himalee S., Park, Sunita I., DeRyckere, Deborah, Raikar, Sunil S., Pauly, Melinda, Summers, Ryan J., Castellino, Sharon M., Wechsler, Daniel S., Porter, Christopher C., Graham, Douglas K., Bhasin, Manoj

“…Acute myeloid leukemia (AML) microenvironment exhibits cellular and molecular differences among various subtypes. Here, we utilize single-cell RNA sequencing…”
Get full text

Pediatric T-cell acute lymphoblastic leukemia blast signature and MRD associated immune environment changes defined by single cell transcriptomics analysis by Bhasin, Swati S., Thomas, Beena E., Summers, Ryan J., Sarkar, Debasree, Mumme, Hope, Pilcher, William, Emam, Mohamed, Raikar, Sunil S., Park, Sunita I., Castellino, Sharon M., Graham, Douglas K., Bhasin, Manoj K., DeRyckere, Deborah

“…Different driver mutations and/or chromosomal aberrations and dysregulated signaling interactions between leukemia cells and the immune microenvironment have…”
Get full text

Utilization of cardiac tests in anthracycline‐treated cancer survivors differs between young adults and children: A claims‐based analysis by Ji, Xu, Hu, Xin, Lipscomb, Joseph, Chow, Eric J., Mertens, Ann C., Castellino, Sharon M.

“…Background The Children's Oncology Group Guidelines recommend a cardiacechocardiogram, or comparable functional imaging, following therapy completion in…”
Get full text

Patterns of surveillance for late effects of BCR-ABL tyrosine kinase inhibitors in survivors of pediatric Philadelphia chromosome positive leukemias by Smith, Stephanie M, Sabnis, Himalee S, Lewis, Rebecca Williamson, Effinger, Karen E, Bergsagel, John, Patterson, Briana, Mertens, Ann, Sakamoto, Kathleen M, Schapira, Lidia, Castellino, Sharon M

“…Targeted anticancer therapies such as BCR-ABL tyrosine kinase inhibitors (TKIs) have improved outcomes for chronic myeloid leukemia (CML) and Philadelphia…”
Get full text

Melphalan induces cardiotoxicity through oxidative stress in cardiomyocytes derived from human induced pluripotent stem cells by Liu, Rui, Li, Dong, Sun, Fangxu, Rampoldi, Antonio, Maxwell, Joshua T, Wu, Ronghu, Fischbach, Peter, Castellino, Sharon M, Du, Yuhong, Fu, Haian, Mandawat, Anant, Xu, Chunhui

“…Treatment-induced cardiotoxicity is a leading noncancer-related cause of acute and late onset morbidity and mortality in cancer patients on antineoplastic…”
Get full text

Oral and dental late effects in survivors of childhood cancer: a Children’s Oncology Group report by Effinger, Karen E., Migliorati, Cesar A., Hudson, Melissa M., McMullen, Kevin P., Kaste, Sue C., Ruble, Kathy, Guilcher, Gregory M. T., Shah, Ami J., Castellino, Sharon M.

“…Purpose Multi-modality therapy has resulted in improved survival for childhood malignancies. The Children’s Oncology Group Long-Term Follow-Up Guidelines for…”
Get full text

Patterns and predictors of clustered risky health behaviors among adult survivors of childhood cancer: A report from the Childhood Cancer Survivor Study by Lown, E. Anne, Hijiya, Nobuko, Zhang, Nan, Srivastava, Deo Kumar, Leisenring, Wendy M., Nathan, Paul C., Castellino, Sharon M., Devine, Katie A., Dilley, Kimberley, Krull, Kevin R., Oeffinger, Kevin C., Hudson, Melissa M., Armstrong, Gregory T., Robison, Leslie L., Ness, Kirsten K.

“…BACKGROUND Health complications related to childhood cancer may be influenced by risky health behaviors (RHBs), particularly when RHBs co‐occur. To the…”
Get full text

Single-cell RNA sequencing distinctly characterizes the wide heterogeneity in pediatric mixed phenotype acute leukemia by Mumme, Hope L, Raikar, Sunil S, Bhasin, Swati S, Thomas, Beena E, Lawrence, Taylor, Weinzierl, Elizabeth P, Pang, Yakun, DeRyckere, Deborah, Gawad, Chuck, Wechsler, Daniel S, Porter, Christopher C, Castellino, Sharon M, Graham, Douglas K, Bhasin, Manoj

“…Abstract Background Mixed phenotype acute leukemia (MPAL), a rare subgroup of leukemia characterized by blast cells with myeloid and lymphoid lineage features,…”
Get full text

Evaluating palliative opportunities in pediatric patients with leukemia and lymphoma by Labudde, Emily J., DeGroote, Nicholas P., Smith, Susie, Ebelhar, Jonathan, Allen, Kristen E., Castellino, Sharon M., Wasilewski‐Masker, Karen, Brock, Katharine E.

“…Background Despite favorable prognoses, pediatric patients with hematologic malignancies experience significant challenges that may lead to diminished quality…”
Get full text

Implementation of a provider-focused intervention for maximizing human papillomavirus (HPV) vaccine uptake in young cancer survivors receiving follow-up care in pediatric oncology practices: protocol for a cluster-randomized trial of the HPV PROTECT intervention by Landier, Wendy, Bhatia, Smita, Richman, Joshua S, Campos Gonzalez, Paula D, Cherven, Brooke, Chollette, Veronica, Aye, Jamie, Castellino, Sharon M, Gramatges, Maria M, Lindemulder, Susan, Russell, Thomas B, Turcotte, Lucie M, Colditz, Graham A, Gilkey, Melissa B, Klosky, James L

“…Childhood cancer survivors are at high risk for developing new cancers (such as cervical and anal cancer) caused by persistent infection with the human…”
Get full text

Clinical covariates that improve the description of high dose methotrexate pharmacokinetics in a diverse population to inform MTXPK.org by Taylor, Zachary L, Miller, Tamara P, Poweleit, Ethan A, DeGroote, Nicholas P, Pommert, Lauren, Awoniyi, Oluwafunbi, Board, Sarah G, Ugboh, Ngozi, Joshi, Vivek, Ambrosino, Nick, Chavana, Ashley, Bernhardt, Melanie B, Schafer, Eric S, O'Brien, Maureen M, Castellino, Sharon M, Ramsey, Laura B

“…The MTXPK.org webtool was launched in December 2019 and was developed to facilitate model-informed supportive care and optimal use of glucarpidase following…”
Get full text

157 Association Between Structural Racism and Acuity of Illness at Initial Presentation in Pediatric Patients with Solid Tumors by Cathcart, Alexandra, Castellino, Sharon M., Sohn, Heeju, DeGroote, Nicholas, Mertens, Ann, Ji, Xu

“…OBJECTIVES/GOALS: Racial/ethnic minoritized children experience poorer cancer outcomes, which may be driven by structural racism. We apply an index that…”
Get full text

Performance of the FACT-GOG-Ntx to assess chemotherapy-induced peripheral neuropathy (CIPN) in pediatric high risk Hodgkin lymphoma: report from the Children’s Oncology Group AHOD 1331 study by Parsons, Susan K., Rodday, Angie Mae, Pei, Qinglin, Keller, Frank G., Wu, Yue, Henderson, Tara O., Cella, David, Kelly, Kara M., Castellino, Sharon M.

“…Background Chemotherapy-induced peripheral neuropathy (CIPN) is an under-recognized complication of several chemotherapy agents used as part of curative-intent…”
Get full text

Cost, Value, and Financial Hardship in Cancer Care: Implications for Pediatric Oncology by Parsons, Susan K, Castellino, Sharon M, Yabroff, K Robin

“…Cancer care in the United States faces a perfect storm: an aging population and expected increased cancer incidence, growing numbers of cancer survivors with…”
Get more information

Association of race/ethnicity with innate immune tumor microenvironment of children with B-acute lymphoblastic leukemia by Gilbert, Julie R, Sabnis, Himalee S, Radzievski, Roman, Doxie, Deon B, DeRyckere, Deborah, Castellino, Sharon M, Dhodapkar, Kavita

“…BackgroundBlack and Hispanic children with B-acute lymphoblastic leukemia (B-ALL) experience worse outcomes compared with their non-Hispanic white (NHW)…”
Get full text