Search Results - "Castellini, Lawrence W."

Variations in DNA elucidate molecular networks that cause disease by Chen, Yanqing, Zhu, Jun, Lum, Pek Yee, Yang, Xia, Pinto, Shirly, MacNeil, Douglas J., Zhang, Chunsheng, Lamb, John, Edwards, Stephen, Sieberts, Solveig K., Leonardson, Amy, Castellini, Lawrence W., Wang, Susanna, Champy, Marie-France, Zhang, Bin, Emilsson, Valur, Doss, Sudheer, Ghazalpour, Anatole, Horvath, Steve, Drake, Thomas A., Lusis, Aldons J., Schadt, Eric E.

“…Identifying variations in DNA that increase susceptibility to disease is one of the primary aims of genetic studies using a forward genetics approach. However,…”
Get full text

Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels by Cervino, Alessandra C., Li, Guoya, Edwards, Steve, Zhu, Jun, Laurie, Cathy, Tokiwa, George, Lum, Pek Yee, Wang, Susanna, Castellini, Lawrence W., Lusis, Aldons J., Carlson, Sonia, Sachs, Alan B., Schadt, Eric E.

“…The use of inbred strains of mice to dissect the genetic complexity of common diseases offers a viable alternative to human studies, given the control over…”
Get full text