Search Results - "Castelli, Giovanna Parenti"

Role of Mitochondria in Oxidative Stress and Aging by LENAZ, GIORGIO, BOVINA, CARLA, D'AURELIO, MARILENA, FATO, ROMANA, FORMIGGINI, GABRIELLA, GENOVA, MARIA LUISA, GIULIANO, GIOVANNI, PICH, MILENA MERLO, PAOLUCCI, UGO, CASTELLI, GIOVANNA PARENTI, VENTURA, BARBARA

“…The mitochondrial respiratory chain is a powerful source of reactive oxygen species (ROS), considered as the pathogenic agent of many diseases and of aging. We…”
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Mitochondrial production of oxygen radical species and the role of Coenzyme Q as an antioxidant by Genova, Maria Luisa, Pich, Milena Merlo, Biondi, Annalisa, Bernacchia, Andrea, Falasca, Anna, Bovina, Carla, Formiggini, Gabriella, Parenti Castelli, Giovanna, Lenaz, Giorgio

“…The mitochondrial respiratory chain is a powerful source of reactive oxygen species (ROS), which is considered as the pathogenic agent of many diseases and of…”
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The mitochondrial respiratory chain is partially organized in a supercomplex assembly: kinetic evidence using flux control analysis by Bianchi, Cristina, Genova, Maria Luisa, Parenti Castelli, Giovanna, Lenaz, Giorgio

“…The model of the respiratory chain in which the enzyme complexes are independently embedded in the lipid bilayer of the inner mitochondrial membrane and…”
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Steady-State Kinetics of the Reduction of Coenzyme Q Analogs by Complex I (NADH:Ubiquinone Oxidoreductase) in Bovine Heart Mitochondria and Submitochondrial Particles by Fato, Romana, Estornell, Ernesto, Di Bernardo, Salvatore, Pallotti, Francesco, Parenti Castelli, Giovanna, Lenaz, Giorgio

“…The reduction kinetics of coenzyme Q (CoQ, ubiquinone) by NADH:ubiquinone oxidoreductase (complex I, EC 1.6.99.3) was investigated in bovine heart…”
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Structural and functional organization of Complex I in the mitochondrial respiratory chain by Bianchi, Cristina, Fato, Romana, Genova, Maria Luisa, Castelli, Giovanna Parenti, Lenaz, Giorgio

“…Metabolic flux control analysis of NADH oxidation in bovine heart submitochondrial particles revealed high flux control coefficients for both Complex I and…”
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The Mitochondrial Production of Reactive Oxygen Species in Relation to Aging and Pathology by GENOVA, MARIA LUISA, PICH, MILENA MERLO, BERNACCHIA, ANDREA, BIANCHI, CRISTINA, BIONDI, ANNALISA, BOVINA, CARLA, FALASCA, ANNA IDA, FORMIGGINI, GABRIELLA, CASTELLI, GIOVANNA PARENTI, LENAZ, GIORGIO

“…: Mitochondria are known to be strong producers of reactive oxygen species (ROS) and, at the same time, particularly susceptible to the oxidative damage…”
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Ubiquinol and a coenzyme Q reducing system protect platelet mitochondrial function of transfusional buffy coats from oxidative stress by Merlo Pich, Milena, Castagnoli, Alida, Biondi, Annalisa, Bernacchia, Andrea, Tazzari, Pier Luigi, D'Aurelio, Marilena, Parenti Castelli, Giovanna, Formiggini, Gabriella, Conte, Roberto, Bovina, Carla, Lenaz, Giorgio

“…The conditions under which Coenzyme Q (CoQ) may protect platelet mitochondrial function of transfusional buffy coats from aging and from induced oxidative…”
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Impairment of mitochondrial oxidative phosphorylation in rat fatty liver exposed to preservation-reperfusion injury by Caraceni, Paolo, Bianchi, Cristina, Domenicali, Marco, Maria Pertosa, Anna, Maiolini, Elisabetta, Parenti Castelli, Giovanna, Nardo, Bruno, Trevisani, Franco, Lenaz, Giorgio, Bernardi, Mauro

“…As the impairment of the cellular energy metabolism contributes to the failure of fatty liver grafts after transplantation, we aimed to determine whether…”
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Yessotoxin, a shellfish biotoxin, is a potent inducer of the permeability transition in isolated mitochondria and intact cells by Bianchi, Cristina, Fato, Romana, Angelin, Alessia, Trombetti, Fabiana, Ventrella, Vittoria, Borgatti, Anna Rosa, Fattorusso, Ernesto, Ciminiello, Patrizia, Bernardi, Paolo, Lenaz, Giorgio, Castelli, Giovanna Parenti

“…The diarrhetic poisoning by bivalve molluscs, diarrhetic shellfish poisoning, is due to consumption of mussels containing biotoxins produced by some…”
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Determination of partition and lateral diffusion coefficients of ubiquinones by fluorescence quenching of n-(9-anthroyloxy)stearic acids in phospholipid vesicles and mitochondrial membranes by Fato, Romana, Battino, Maurizio, Degli Esposti, Mauro, Parenti Castelli, Giovanna, Lenaz, Giorgio

“…The quenching of fluorescence of n-(9-anthroyloxy)stearic acids and other probes by different ubiquinone homologues and analogues has been exploited to assess…”
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The Mitochondrial Respiratory Chain Is Partially Organized in a Supercomplex Assembly by Bianchi, Cristina, Genova, Maria Luisa, Parenti Castelli, Giovanna, Lenaz, Giorgio

“…The model of the respiratory chain in which the enzyme complexes are independently embedded in the lipid bilayer of the inner mitochondrial membrane and…”
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Decreased Pasteur effect in platelets of aged individuals by D'Aurelio, Marilena, Merlo Pich, Milena, Catani, Lucia, Sgarbi, Gian Luca, Bovina, Carla, Formiggini, Gabriella, Castelli, Giovanna Parenti, Baum, Harold, Tura, Sante, Lenaz, Giorgio

“…We have investigated the mitochondrial energy state in human platelets of young (19–30 years old) and aged individuals (65–87 years old) exploiting the Pasteur…”
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Localization and mobility of coenzyme Q in lipid bilayers and membranes by Lenaz, Giorgio, Fato, Romana, Di Bernardo, Salvatore, Jarreta, Diana, Costa, Angela, Genova, Maria Luisa, Castelli, Giovanna Parenti

“…We have studied the mobility of coenzyme Q (CoQ) in lipid bilayers and mitochondrial membranes in relation to the control of electron transfer activities. A…”
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The site of production of superoxide radical in mitochondrial Complex I is not a bound ubisemiquinone but presumably iron–sulfur cluster N2 by Genova, Maria Luisa, Ventura, Barbara, Giuliano, Giovanni, Bovina, Carla, Formiggini, Gabriella, Parenti Castelli, Giovanna, Lenaz, Giorgio

“…The mitochondrial respiratory chain is a powerful source of reactive oxygen species, considered as the pathogenic agent of many diseases and of aging. We have…”
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Mitochondrial complex I defects in aging by Lenaz, G, Bovina, C, Castelluccio, C, Fato, R, Formiggini, G, Genova, M.L, Marchetti, M, Pich, M.M, Pallotti, F, Castelli, G.P

“…According to the 'mitochondrial theory of aging' it is expected that the activity of NADH Coenzyme Q reductase (Complex I) would be most severely affected…”
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Mitochondria, oxidative stress, and antioxidant defences by Lenaz, G, Bovina, C, Formiggini, G, Parenti Castelli, G

“…Mitochondria are strongly involved in production of reactive oxygen species, considered today as the main pathogenic agent of many diseases. A vicious circle…”
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The inhibition of NADH oxidase by the lower homologs of coenzyme Q by Lenaz, G, Pasquali, P, Bertoli, E, Parenti-Castelli, G

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The effect of aging and an oxidative stress on peroxide levels and the mitochondrial membrane potential in isolated rat hepatocytes by Cavazzoni, Marika, Barogi, Silvia, Baracca, Alessandra, Parenti Castelli, Giovanna, Lenaz, Giorgio

“…We have investigated the effect of ageing and of adriamycin treatment on the bioenergetics of isolated rat hepatocytes. Ageing per se, whilst being associated…”
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Enhanced Activity of the Plasma Membrane Oxidoreductase in Circulating Lymphocytes from Insulin-Dependent Diabetes Mellitus Patients by Lenaz, Giorgio, Paolucci, Ugo, Fato, Romana, D'Aurelio, Marilena, Parenti Castelli, Giovanna, Sgarbi, Gianluca, Biagini, Graziella, Ragni, Luca, Salardi, Silvana, Cacciari, Emanuele

“…Circulating human lymphocytes contain a transmembrane oxidoreductase (PMOR) capable of reducing dichlorophenol indophenol (DCIP) by endogenous reductants,…”
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Fatty degeneration exacerbates mitochondrial dysfunction in the rat liver exposed to preservation-reperfusion injury by Caraceni, Paolo, Domenicali, Marco, Bianchi, Cristina, Maiolini, Elisabetta, Parenti-Castelli, Giovanna, Lenaz, Giorgio, Trevisani, Franco, Bernardi, Mauro

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