Search Results - "Castellano, Luciana A"

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    Translation affects mRNA stability in a codon-dependent manner in human cells by Wu, Qiushuang, Medina, Santiago Gerardo, Kushawah, Gopal, DeVore, Michelle Lynn, Castellano, Luciana A, Hand, Jacqelyn M, Wright, Matthew, Bazzini, Ariel Alejandro

    Published in eLife (23-04-2019)
    “…mRNA translation decodes nucleotide into amino acid sequences. However, translation has also been shown to affect mRNA stability depending on codon composition…”
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    Dengue virus preferentially uses human and mosquito non-optimal codons by Castellano, Luciana A, McNamara, Ryan J, Pallarés, Horacio M, Gamarnik, Andrea V, Alvarez, Diego E, Bazzini, Ariel A

    Published in Molecular systems biology (03-10-2024)
    “…Codon optimality refers to the effect that codon composition has on messenger RNA (mRNA) stability and translation level and implies that synonymous codons are…”
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    Poly(A) tails: longer is not always better by Castellano, Luciana A, Bazzini, Ariel A

    Published in Nature structural & molecular biology (01-12-2017)
    “…Deadenylation of mRNAs is generally associated with translational inhibition and mRNA decay. A study now reports that, unexpectedly, highly expressed genes…”
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